The thermo-chemical treatment of oxy-nitrocarburizing consists in the enrichment of materials in C, N and O in order to improve the physico-mechanical properties and the use of the materials. This leads to the increase in exploitation life, the increase of wear resistance, galling, corrosion, and slight erosion. The research presented in this article followed the study of the application of this treatment and the results obtained on pearlitic grey cast iron with different chemical compositions, domain in which there are few experimental results published. The results obtained on a number of 10 samples, presented in the article, highlighted the good compatibility of these materials with the thermo-chemical treatment of oxy-nitrocarburizing, obtaining on the surface some white layers which give good anti-corrosive properties, similar to those obtained on steel. There was no correlation between the depth of the white layer and the chemical composition of the studied cast iron. It was also emphasized that the depth of nitrogen diffusion is influenced by the chemical composition of the studied materials which is directly proportional to carbon equivalent (Ceq) of cast iron.