Antioxidant Properties and Mechanisms of Tea Polyphenols

2008 ◽  
pp. 131-159 ◽  
Author(s):  
Zhengzhu Zhang ◽  
Xiaochun Wan ◽  
Daxiang Li
Keyword(s):  
Antioxidant Properties ◽  
Tea Polyphenols

scholarly journals Antioxidant properties of green tea polyphenols encapsulated in caseinate beads

2009 ◽  
Vol 89 (6) ◽  
pp. 627-485 ◽  
Author(s):  
Masood Dehkharghanian ◽  
Stéphane Salmieri ◽  
Monique Lacroix ◽  
Mookambeswaran A. Vijayalakshmi
Keyword(s):  
Green Tea ◽  
Antioxidant Properties ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols

scholarly journals Evaluation of the Antioxidant Interactions Between Green Tea Polyphenols and Nonsteroidal Anti-inflammatory Drugs

2019 ◽  
Vol 6 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Aleksandra Sentkowska ◽  
Krystyna Pyrzynska
Keyword(s):  
Green Tea ◽  
Antioxidant Properties ◽  
Antagonistic Effect ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
High Concentration ◽  
Tea Infusion ◽  
Scavenging Effect ◽  
Interaction Factors ◽  
Tea Extract

Introduction: The antioxidant interactions between the commonly used pharmaceuticals (diclofenac, ibuprofen and naproxen) and green tea polyphenols were evaluated. Methods: The antioxidant properties of the mixtures were evaluated by a scavenging effect on the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical. Results: The mixtures contained green tea extract and each drug exhibited lower antioxidant activity than the mathematical sum of the results obtained for individual components showing antagonistic effect. The results were obtained using isobolographic analysis and interaction factors also suggested the antagonistic type of interaction. Only when the concentration of the green tea infusion was relatively high (in comparison to the drug), an additive effect could be concluded. Conclusion: The high concentration of green tea infusion in comparison to the drug should be used in developing the new formulations as it can help in the therapy due to their antioxidant properties.

scholarly journals Antioxidant Properties of a Traditional Vine Tea, Ampelopsis grossedentata

Antioxidants ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 295 ◽  
Author(s):  
Kun Xie ◽  
Xi He ◽  
Keyu Chen ◽  
Jihua Chen ◽  
Kozue Sakao ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Ultrasonic Treatment ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Tea Polyphenols ◽  
Related Factor ◽  
Quinone Oxidoreductase ◽  
Ampelopsis Grossedentata

Ampelopsis grossedentata, also called vine tea, has been used as a traditional beverage in China for centuries. Vine tea contains rich polyphenols and shows benefit to human health, but the chemical and antioxidant properties of vine tea polyphenols from different locations remain unclear. This study aims to investigate the chemical and antioxidant properties of vine tea from three major production areas in China including Guizhou, Hunan, and Guangxi Provinces. The highest amount of polyphenol from vine tea was extracted by 70% ethanol at 70 °C for 40 min with ultrasonic treatment. The major compound in vine tea polyphenols (VTP) was determined as dihydromyricetin (DMY) by high-performance liquid chromatography (HPLC) and the content was estimated as 21.42%, 20.17%, and 16.47% of dry weight basis from Hunan, Guizhou, and Guangxi products, respectively. The antioxidant activities were investigated in vitro and in culture hepatic cells. VTP and DMY showed strong 1,1-Diphenyl-2-picrylhydrazyl free radical (DPPH) scavenging ability and high oxygen radical absorption capacity (ORAC) value in vitro. VTP and DMY also increased the level of nicotinamide adenine dinucleotide phosphate (NADPH):quinone oxidoreductase (NQO1) in HepG2 cells. Moreover, VTP and DMY enhanced the level of nuclear factor erythroid 2-related factor 2 (Nrf2) and reduced the level of Kelch-like ECH-associated protein 1 (Keap1). Taken together, our data demonstrated that the extraction of vine tea by 70% ethanol with ultrasonic treatment is a novel method to efficiently obtain components possessing stronger antioxidant activity. Furthermore, the results from the culture cells suggest that the bioactive component of vine tea might exert the antioxidant activity by activating the cellular Nrf2/Keap1 pathway.

scholarly journals Optimization Research into the Ultrasonic-assisted Extraction to Separate Polyphenol from Green Tea Waste

2013 ◽  
Vol 12 (2) ◽  
pp. 52 ◽  
Author(s):  
Lan Huong Phung ◽  
Trung Kien Tran ◽  
The Cuong Nguyen ◽  
Hong Quang Do ◽  
Thu Tra Phan ◽  
...  
Keyword(s):  
Green Tea ◽  
Antioxidant Properties ◽  
Hot Water ◽  
Tea Polyphenols ◽  
Tea Leaves ◽  
Water Solvent ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Green Tea Leaves ◽  
Ultrasonic Assisted Extraction

Today, green tea leaves (Camellia sinensis) have been grown in nearly 30 provinces in Vietnam. Catechins, which are polyphenols, are abundant in green tea. In a freshly picked tea leaf, polyphenols can compose up to 30% of the dry weight. Recently, researchs have focused on tea polyphenols due to its potent anti-oxidant activity, anti-inflammatory and anti-cancer effects. Viet Nam currently ranks the fifth in the world in tea production and export turn-over. However, green tea is made from the top two leaves and buds of a shrub. A large amount of stems, older leaves and tea wastes from tea factories is not produced. For this reason, study to separation polyphenols from these materials plays an important role in science, society and economy. Polyphenols can be extracted from green tea leaves by using hot water and organic solvents. In the method of using hot water, green tea quality deteriorates and catechins are destroyed due to the heat applied. Therefore, we attempted to increase the amount of polyphenols in extracts with using ultrasonic irradiation at low temperature. This work has an aim to investigate the influent process parameters such as extraction time, stirring speed and the rate of raw material/solvent on efficiency of the extraction of polyphenols and antioxidant properties obtained extracts. The ultrasonic-assisted extraction was conducted at room temperature, ultrasound frequency (25 kHz) using water solvent. Extracts were analysed for total phenols content (TPC) by the Lowenthal method. The antioxidant properties have been determined by DPPH free radical scavenging effect, The results of the work are the basis to determine of the optimal technological factors by employing desirability methodology with experimental order of Box-Behnken design and to scale up for designed industrial extraction system that can be applied in tea plants for the production of tea polyphenols from tea wastes.

scholarly journals Liver Injury Induced by Carbon Tetrachloride in Mice Is Prevented by the Antioxidant Capacity of Anji White Tea Polyphenols

Antioxidants ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 64 ◽  
Author(s):  
Ranran Wang ◽  
Zhiqing Yang ◽  
Jing Zhang ◽  
Jianfei Mu ◽  
Xianrong Zhou ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Injury ◽  
Antioxidant Capacity ◽  
Liver Tissue ◽  
Quantitative Polymerase Chain Reaction ◽  
Interleukin 1 ◽  
Antioxidant Properties ◽  
Tea Polyphenols ◽  
Nuclear Factor ◽  
White Tea

Anji white tea is a unique variety of green tea that is rich in polyphenols. In this study, the effect of Anji white tea polyphenols (AJWTP) on the prevention of carbon tetrachloride (CCl4)-induced liver injury through its antioxidant properties was studied. Biochemical and molecular biology methods were used to analyze the serum and liver tissue of mice. The antioxidant capacity and liver injury preventive effect of AJWTP were determined, and the mechanism was elaborated. The results showed that AJWTP decreased the serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglyceride (TG), and total cholesterol (TC) in mice with liver injury, it increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the serum and liver tissue of mice with liver injury, and it also decreased the amount of malondialdehyde (MDA). Further quantitative polymerase chain reaction (qPCR) results showed that AJWTP upregulated the mRNA expression of Cu/Zn-SOD, Mn-SOD, catalase (CAT), and nuclear factor of kappa light polypeptide gene enhancer in B-cell inhibitor alpha (IκB-α) and downregulated the expression of nuclear factor κ-light-chain-enhancer of activated B-cells (NF-κB), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), interleukin-1 beta (IL-1β), and tumor necrosis factor alpha (TNF-α) in the liver tissue of mice with liver injury. Therefore, AJWTP produces sufficient antioxidant action to prevent liver injury, and the effect increases with the increase in AJWTP concentration. The effect of 200 mg/kg AJWTP was similar to that of the same concentration of the drug (silymarin) used for the treatment of liver injury. This indicates excellent potential for the development and utilization of AJWTP because it is an active substance with excellent antioxidant effects and can prevent liver injury.

scholarly journals Tea polyphenols on emulsifying and antioxidant properties of egg white protein at acidic and neutral pH conditions

LWT ◽  
2021 ◽  
pp. 112537
Author(s):  
Jun Sun ◽  
Tengmei Liu ◽  
Feng Zhang ◽  
Yuqian Huang ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Antioxidant Properties ◽  
Egg White ◽  
Tea Polyphenols ◽  
Egg White Protein ◽  
Neutral Ph ◽  
Ph Conditions

scholarly journals High-polyphenol extracts from Sorghum bicolor attenuate replication of Legionella pneumophila within RAW 264.7 macrophages

2019 ◽  
Author(s):  
Aubrey M. Gilchrist ◽  
Dmitriy Smolensky ◽  
Sarah Cox ◽  
Ramasamy Perumal ◽  
Leela E. Noronha ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Sorghum Bicolor ◽  
Legionella Pneumophila ◽  
Antioxidant Properties ◽  
Tea Polyphenols ◽  
Raw 264.7 ◽  
Dependent Manner ◽  
Intracellular Replication ◽  
Mouse Macrophages ◽  
The Impact

AbstractPolyphenols derived from a variety of plants have demonstrated antimicrobial activity against diverse microbial pathogens. Legionella pneumophila is an intracellular bacterial pathogen that opportunistically causes a severe inflammatory pneumonia in humans, called Legionnaires’ Disease, via replication within macrophages. Previous studies demonstrated that tea polyphenols attenuate L. pneumophila intracellular replication within mouse macrophages via amplification of tumor necrosis factor (TNF) production. Sorghum bicolor is a sustainable and resilient cereal crop that thrives in arid environments and is well suited to continued production in warming climates. Polyphenols derived from sorghum have anticancer and antioxidant properties, but their antimicrobial activity has not been evaluated. Here, we investigated the impact of sorghum polyphenols on L. pneumophila intracellular replication within RAW 264.7 mouse macrophages. We discovered that sorghum high-polyphenol extract (HPE) treatment attenuates L. pneumophila intracellular replication in a dose-dependent manner. Sorghum HPE did not impair bacterial replication in vitro or impact macrophage viability. Moreover, in contrast to tea polyphenols, HPE treatment impaired TNF secretion from infected macrophages. Thus, polyphenols derived from sorghum enhance macrophage restriction of L. pneumophila by a novel mechanism. This work provides a foundation for the use of sorghum as an antimicrobial agent.

Sign in / Sign up

Export Citation Format

Share Document