Effect of Manufacturing and Absorption Promotion of Lidocaine Hydrogel Using Ultrasonic Waves during Cosmetic Procedures

Purpose: In this study, we study to more effectively use anesthesia products used in beauty procedures following the popularization of anti-aging. Hydrogel, which contains lidocaine, is believed to be more effective in relieving pain if used in cosmetic procedures with ultrasonic waves.Methods: The availability of manufactured hydrogels and commercial gels for ultrasonic treatment was compared, and the effect on skin penetration and skin penetration due to ultrasonic limitations was evaluated based on their applicability. Usability and optimal ultrasound parameters were identified during ultrasound treatment.Results: Viscosity measurement, gelation rate, swelling, skin permeability experiment, and HPLC analysis of manufactured hydrogels all revealed properties, with skin permeability being highest at frequency 1 MHz, cycle low 200, and high 50.Conclusions: Finally, hydrogels containing lidocaine increased skin permeability during ultrasound treatment, allowing for faster targeted transdermal transmission that was more effective depending on the ultrasound parameters. As a result, it is determined that it can be used in cosmetic procedures.

Efficiency of ultrasonic treatment of polysaccharide from brown algae

Ultrasonic exposure can be used for depolymerization of brown algae polysaccharides. However, its effectiveness depends on several factors, including cavitation activity in the treatment medium. Therefore, the purpose of the work was to determine the cavitation activity and the effectiveness of the ultrasonic exposure to fucoidan in order to optimize the processing processes of polysaccharide from brown algae. A change in cavitation activity was revealed depending on the composition of the processing environment, as well as on the intensity of ultrasonic exposure with a constant frequency of the ultrasonic wave. Similar dynamics of change of cavitation activity were established at the intensity of ultrasonic treatment of 100 and 133 W/cm2 with amplification of electric signal at the increase of ultrasound intensity. The use of SDS in the processing medium led to an increase in cavitation activity to 14.9±0.47 mV. Treatment of the fucoidan solution for 40 minutes under various conditions allowed to obtain fractions with a change in the average hydrodynamic particle diameter from 113 nm (100 W/cm2) to 85 nm (200 W/cm2) and 124 nm (SDS).

Thermal conduction characteristics of silicone composites including ultrasonic-treated graphite

The microstructural change of graphite was studied after ultrasonic treatment of the graphite. When the graphite solution was treated with varying ultrasonic power and time, the microstructure changed gradually, and accordingly, the thermal conductivity characteristics of the composite containing the as-treated graphite was also different with each other. Thermal conductivity showed the best result in the silicone composite containing graphite prepared under the optimum condition of ultrasonic treatment, and the thermal conductivity of the composite improved proportionally along with the particle size of graphite. When the silicone composite was prepared by using a mixture of inorganic oxides and graphite rather than graphite alone, the thermal conductivity of the silicone composite was further increased. A silicone composite containing graphite was used for LED (light emitting diode) lighting system as a thermal interface material (TIM), and the temperature elevation due to heat generated, while the lighting was actually operated, was analyzed.