AAC 2.3 Determination of the compressive strength of AAC for whole units directly after autoclaving (manufacturing control method)

1994 ◽  
pp. 319-319
Keyword(s):  
Compressive Strength ◽  
Control Method ◽  
Manufacturing Control

Determination of Concrete Cube Strength from Used Samples / Určení Krychelné Pevnosti Betonu U Použitých Zkušebních Trámců

2012 ◽  
Vol 12 (2) ◽  
pp. 186-194 ◽  
Author(s):  
Oldřich Sucharda ◽  
David Mikolášek ◽  
Jiří Brožovský
Keyword(s):  
Compressive Strength ◽  
Concrete Beams ◽  
Linear Analysis ◽  
Bending Tests ◽  
Cube Strength ◽  
Non Linear ◽  
Compressive Strength Of Concrete ◽  
Concrete Cube

Abstract This paper deals with the determination of compressive strength of concrete. Cubes, cylinders and re-used test beams were tested. The concrete beams were first subjected to three-point or fourpoint bending tests and then used for determination of the compressive strength of concrete. Some concrete beams were reinforced, while others had no reinforcement. Accuracy of the experiments and calculations was verified in a non-linear analysis.

Fast Method for the Determination of Residual Solvents in Radiopharmaceutical Products

2017 ◽  
Vol 68 (4) ◽  
pp. 666-670 ◽  
Author(s):  
Mirela Mihon ◽  
Catalin Stelian Tuta ◽  
Alina Catrinel Ion ◽  
Dana Niculae ◽  
Vasile Lavric
Keyword(s):  
Gas Chromatography ◽  
Control Method ◽  
Limit Of Detection ◽  
The Body ◽  
Biologically Active ◽  
Injection Technique ◽  
Fast Method ◽  
Residual Solvent ◽  
Residual Solvents

The aim of this work was the development and validation of a fast analytical method to determine the residual solvents content in radiopharmaceuticals such as: 18F-Fluorodeoxyglucose (18F-FDG), 18F-Fluoroestradiol (18F-FES), 18F-Fluorothymidine (18F-FLT),18F-Fluoromisonidazole (18F-FMISO). Radiopharmaceuticals are radioactive preparations for medical purposes used in nuclear medicine as tracers in diagnostic imaging and treatment of certain diseases. Positron Emission Tomography (PET) is a medical imaging technique that consists in introducing into the body of a small amount of a biologically active chemical compound labelled with a short lived positron-emitting radioisotope (18F, 11C, 68Ga). Residual solvents are critical impurities in radiopharmaceuticals that can affect labelling, stability and physicochemical properties of drugs. Therefore, the determination of these solvents is essential for quality control of radiopharmaceuticals. Validation of the control method for residual solvents by gas chromatography is referred by the European Pharmacopoeia using a special injection technique (head space). The parameters of the method, which comply with International Conference on Harmonization guidelines, are: accuracy, precision, linearity, limit of detection, limit of quantification and robustness. The proposed method (direct gas chromatography injection) proved to be linear, precise, accurate and robust. Good linearity was achieved for all the solvents and correlation coefficients (R2) for each residual solvent were found more than 0.99.

scholarly journals Machine Learning Approaches for Prediction of the Compressive Strength of Alkali Activated Termite Mound Soil

2021 ◽  
Vol 11 (11) ◽  
pp. 4754
Author(s):  
Assia Aboubakar Mahamat ◽  
Moussa Mahamat Boukar ◽  
Nurudeen Mahmud Ibrahim ◽  
Tido Tiwa Stanislas ◽  
Numfor Linda Bih ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Construction Materials ◽  
Curing Temperature ◽  
Sustainable Construction ◽  
Support Vector ◽  
Learning Approaches ◽  
Artificial Neural Network Ann ◽  
Curing Regime ◽  
Alkali Activated

Earth-based materials have shown promise in the development of ecofriendly and sustainable construction materials. However, their unconventional usage in the construction field makes the estimation of their properties difficult and inaccurate. Often, the determination of their properties is conducted based on a conventional materials procedure. Hence, there is inaccuracy in understanding the properties of the unconventional materials. To obtain more accurate properties, a support vector machine (SVM), artificial neural network (ANN) and linear regression (LR) were used to predict the compressive strength of the alkali-activated termite soil. In this study, factors such as activator concentration, Si/Al, initial curing temperature, water absorption, weight and curing regime were used as input parameters due to their significant effect in the compressive strength. The experimental results depict that SVM outperforms ANN and LR in terms of R2 score and root mean square error (RMSE).

scholarly journals Development and Validation of a GMP-Compliant High-Pressure Liquid Chromatography Method for the Determination of the Chemical and Radiochemical Purity of [18F]PSMA-1007, a PET Tracer for the Imaging of Prostate Cancer

2021 ◽  
Vol 14 (3) ◽  
pp. 188
Author(s):  
Ines Katzschmann ◽  
Heike Marx ◽  
Klaus Kopka ◽  
Ute Hennrich
Keyword(s):  
Prostate Cancer ◽  
Quality Control ◽  
Radiochemical Purity ◽  
Control Method ◽  
Solid Phase ◽  
Hplc Method ◽  
Attractive Alternative ◽  
Chromatography Method ◽  
Pet Tracer

For the PET imaging of prostate cancer, radiotracers targeting the prostate-specific membrane antigen (PSMA) are nowadays used in clinical practice. [18F]PSMA-1007, a radiopharmaceutical labeled with fluorine-18, has excellent properties for the detection of prostate cancer. Essential for the human use of a radiotracer is its production and quality control under GMP-compliance. For this purpose, all analytical methods have to be validated. [18F]PSMA-1007 is easily radiosynthesized in a one-step procedure and isolated using solid phase extraction (SPE) cartridges followed by formulation of a buffered injection solution and for the determination of its chemical and radiochemical purity a robust, fast and reliable quality control method using radio-HPLC is necessary. After development and optimizations overcoming problems in reproducibility, the here described radio-HPLC method fulfills all acceptance criteria—for e.g., specificity, linearity, and accuracy—and is therefore well suited for the routine quality control of [18F]PSMA-1007 before release of the radiopharmaceutical. Recently a European Pharmacopeia monograph for [18F]PSMA-1007 was published suggesting a different radio-HPLC method for the determination of its chemical and radiochemical purity. Since the here described method has certain advantages, not least of all easier technical implementation, it can be an attractive alternative to the monograph method. The here described method was successfully validated on several radio-HPLC systems in our lab and used for the analysis of more than 60 batches of [18F]PSMA-1007. Using this method, the chemical and radiochemical purity of [18F]PSMA-1007 can routinely be evaluated assuring patient safety.

Rapid determination of soil unconfined compressive strength using reflectance spectroscopy

2021 ◽  
Vol 80 (5) ◽  
pp. 3923-3938
Author(s):  
Fatemeh Mousavi ◽  
Ehsan Abdi ◽  
Parviz Fatehi ◽  
Abbas Ghalandarzadeh ◽  
Hossein Ali Bahrami ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Unconfined Compressive Strength ◽  
Rapid Determination ◽  
Reflectance Spectroscopy

scholarly journals Increased resilience for manufacturing systems in supply networks through data-based turbulence mitigation

2021 ◽  
Author(s):  
Dennis Bauer ◽  
Markus Böhm ◽  
Thomas Bauernhansl ◽  
Alexander Sauer
Keyword(s):  
Manufacturing Systems ◽  
Control Method ◽  
Great Influence ◽  
Learning System ◽  
Effective Control ◽  
Sufficient Information ◽  
Short Term ◽  
Data Format ◽  
Supply Networks ◽  
Manufacturing Control

AbstractIn manufacturing systems, a state of high resilience is always desirable. However, internal and external complexity has great influence on these systems. An approach is to increase manufacturing robustness and responsiveness—and thus resilience—by manufacturing control. In order to execute an effective control method, it is necessary to provide sufficient information of high value in terms of data format, quality and time of availability. Nowadays, raw data is available in large quantities. An obstacle to manufacturing control is the short-term handling of events induced by customers and suppliers. These events cause different kinds of turbulence in manufacturing systems. If such turbulences could be evaluated in advance, based on data processing, they could serve as aggregated input data for a control system. This paper presents an approach how to combine turbulence evaluation and the derivation of measures into a learning system for turbulence mitigation. Integrated in manufacturing control, turbulence mitigation increases manufacturing resilience and strengthens the supply network’s resilience.

Caracterización de la roca mediante propiedades físicas y su relación con la resistencia a la compresión simple

2021 ◽  
Vol 2 (4) ◽  
pp. 5081-5093
Author(s):  
Patricio Feijoo Calle ◽  
Elizabeth Brito Verdezoto
Keyword(s):  
Compressive Strength ◽  
Physical Properties ◽  
Unconfined Compressive Strength ◽  
Approximate Determination ◽  
Practical Application ◽  
Calculation Methodology

En este trabajo se propone una metodología sencilla y de aplicación práctica en campo para la determinación aproximada de la Resistencia a la Compresión Simple (RCS) en rocas, propiedad o característica que es importante en minería, ya que mediante la misma, se ejecutan análisis para la valoración de factores de seguridad y estabilidad y/o posibles sistemas de fortificación en las obras o estructuras mineras, a más de que la caracterización de la RCS es también influyente en el uso de explosivos para la explotación o extracción de materiales de una cantera o mina. Esta estimación se la propone en base a la determinación de las siguientes tres propiedades de la roca, que en esta investigación las denominamos densidad, porosidad y absorción “en mina”. Estas propiedades físicas se las puede obtener de una forma simple, pero metódica y en este trabajo se han ejecutado ensayos sobre un mismo material o roca proveniente de la zona de Cojitambo, provincia del Cañar (Ecuador) y sobre una base de 60 muestras o probetas. Los resultados obtenidos permiten una correlación entre las propiedades antes descritas y la RCS, a más que se ha estructurado una metodología de cálculo para el objetivo planteado.   This work proposes a simple methodology and practical application in the field for the approximate determination of the Unconfined Compressive Strength (UCS) in rocks, property or characteristic that is important in mining, since through it analyzes are carried out to the assessment of security and stability factors and/or possible fortification systems in the works or mining structures, in addition to the characterization of the UCS is also influential in the use of explosives for the exploitation or extraction of materials from a quarry or mine. This estimate is proposed based on the determination of the following three properties of the rock, which in this investigation we call density, porosity and absorption “in mine”. These physical properties can be obtained in a simple, but methodical way and in this work, tests have been carried out on the same material or rock from the Cojitambo area, Cañar province (Ecuador) and on the basis of 60 samples or test tubes. The results obtained allow a correlation between the properties described above and the UCS, in addition to a calculation methodology for the proposed objective.

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