The influence of tumor thickness on the vascular morphologies

2016 ◽  
pp. 41-42
Author(s):  
Iris Zalaudek ◽  
Simonetta Piana ◽  
Cesare Massone
Keyword(s):  
Tumor Thickness

scholarly journals Prognostic value of MRI-measured tumor thickness in patients with tongue squamous cell carcinoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ki-Sun Park ◽  
Yangsean Choi ◽  
Jiwoong Kim ◽  
Kook-Jin Ahn ◽  
Bum-soo Kim ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Value ◽  
Proportional Hazards ◽  
Correlation Coefficients ◽  
Cox Proportional Hazards ◽  
Tumor Thickness ◽  
Tongue Squamous Cell Carcinoma ◽  
Depth Of Invasion

AbstractThis study aimed to assess the prognostic value of MRI-measured tumor thickness (MRI-TT) in patients with tongue squamous cell carcinoma (SCC). This single-center retrospective cohort study included 133 pathologically confirmed tongue SCC patients between January 2009 and October 2019. MRI measurements of tongue SCC were based on axial and coronal T2-weighted (T2WI) and contrast-enhanced T1-weighted (CE-T1WI) images. Two radiologists independently measured MRI-TT. Intraclass correlation coefficients (ICC) were calculated for inter-rater agreements. Spearman’s rank correlation between MRI-TT and pathologic depth of invasion (pDOI) was assessed. Cox proportional hazards analyses on recurrence-free (RFS) and overall survival (OS) were performed for MRI-TT and pDOI. Kaplan–Meier survival curves were plotted with log-rank tests. The intra- and inter-rater agreements of MRI-TT were excellent (ICC: 0.829–0.897, all P < 0.001). The correlation between MRI-TT and pDOI was good (Spearman’s correlation coefficients: 0.72–0.76, P < 0.001). MRI-TT were significantly greater than pDOI in all axial and coronal T2WI and CE-T1WI (P < 0.001). In multivariate Cox proportional hazards analysis, MRI-TT measured on axial CE-T1WI yielded a significant prognostic value for OS (hazards ratio 2.77; P = 0.034). MRI-TT demonstrated excellent intra- and inter-rater agreements as well as high correlation with pDOI. MRI-TT may serve as a prognostic predictor in patients with tongue SCC.

scholarly journals FP05.03 Association between Baseline Tumor Thickness and Response to Neoadjuvant Chemotherapy in Malignant Pleural Mesothelioma

2021 ◽  
Vol 16 (3) ◽  
pp. S200
Author(s):  
N. Zhou ◽  
D. Rice ◽  
R. Mehran ◽  
H. Feldman ◽  
K. Tomczak ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Malignant Pleural Mesothelioma ◽  
Tumor Thickness ◽  
Pleural Mesothelioma ◽  
Response To Neoadjuvant Chemotherapy

EPILUMINESCENCE MICROSCOPY FEATURES OF MELANOMA IN RELATION TO TUMOR THICKNESS

2001 ◽  
Vol 19 (2) ◽  
pp. 285-297 ◽  
Author(s):  
Ignazio Stanganelli ◽  
Silvia Zago ◽  
Alessandro Testori ◽  
Federica Sforzini ◽  
Guido Zannetti ◽  
...  
Keyword(s):  
Tumor Thickness

Endoscopic ultrasound determined maximal tumor thickness is an objective measure of tumor response to chemotherapy in esophageal cancer

1997 ◽  
Vol 45 (4) ◽  
pp. AB62 ◽  
Author(s):  
JP Achkar ◽  
ES Kassis ◽  
J.D. Luketich ◽  
CP Belani ◽  
B.C. Lembersky ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Endoscopic Ultrasound ◽  
Tumor Response ◽  
Objective Measure ◽  
Tumor Thickness ◽  
Response To Chemotherapy

2847 Importance of tumor thickness using intraoral ultrasound in predicting nodal metastasis in early oral cancer

2015 ◽  
Vol 51 ◽  
pp. S573
Author(s):  
J.R. Vishnoi ◽  
S. Gupta ◽  
V. Kumar ◽  
N. Jamal ◽  
P. Agrawal ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Nodal Metastasis ◽  
Tumor Thickness

Efficacy of endoscopic ultrasonography in evaluating tumor thickness in patients with superficial pharyngeal carcinoma: A pilot study

2021 ◽  
Author(s):  
Hidehito Maeda ◽  
Fumisato Sasaki ◽  
Masayuki Kabayama ◽  
Hiromichi Iwaya ◽  
Yuga Komaki ◽  
...  
Keyword(s):  
Pilot Study ◽  
Endoscopic Ultrasonography ◽  
Tumor Thickness ◽  
Pharyngeal Carcinoma

scholarly journals E-Cadherin Expression in Canine Melanocytic Tumors: Histological, Immunohistochemical, and Survival Analysis

2020 ◽  
Vol 57 (5) ◽  
pp. 608-619 ◽  
Author(s):  
Serenella Silvestri ◽  
Ilaria Porcellato ◽  
Luca Mechelli ◽  
Laura Menchetti ◽  
Selina Iussich ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Epithelial Mesenchymal Transition ◽  
Tumor Thickness ◽  
Mesenchymal Transition ◽  
Clark Level ◽  
Melanocytic Tumors ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Favorable Clinical Outcome ◽  
E Cadherin

E-cadherin, a glycoprotein involved in cell-cell adhesion, has a pivotal role in epithelial-mesenchymal transition, a process through which neoplastic epithelial cells develop an invasive phenotype. In human cutaneous melanomas, decreased E-cadherin expression is associated with shorter survival and increased Breslow thickness, whereas in the dog its role is poorly understood. Tumor thickness and modified Clark level were recently proposed as useful features to assess canine melanocytic tumors, but no studies investigated their association with E-cadherin expression. We performed immunohistochemistry on 77 formalin-fixed, paraffin-embedded primary canine melanocytic tumors. A 3-tier and a 2-tier classification system for assessing E-cadherin expression were tested, with the latter being more informative for the assessment of canine melanocytic tumors. E-cadherin expression was lower in cutaneous melanomas than melanocytomas, as well as in amelanotic tumors compared to pigmented tumors. In amelanotic melanomas, absent E-cadherin expression was associated with an unfavorable outcome, suggesting a potential use of this marker in defining the prognosis of amelanotic melanomas. E-cadherin expression was lower in tumors with greater tumor thickness and modified Clark level ≥IV, suggesting its possible utility in identifying the most invasive tumors. The expression of E-cadherin in oral melanomas was heterogeneous, but was associated with pigmentation and clinical outcome; thus, E-cadherin evaluation could be advantageous to detect the most aggressive neoplasms. However, cutaneous melanomas without E-cadherin expression frequently had a favorable clinical outcome. Hence, its importance as prognostic factor should be carefully considered depending on the tumor origin.

Greater Tumor Thickness, Ulceration, and Positive Sentinel Lymph Node are Associated With Worse Prognosis in Patients With Conjunctival Melanoma

2019 ◽  
pp. 1 ◽  
Author(s):  
Bita Esmaeli ◽  
Maria Laura Rubin ◽  
Shiqiong Xu ◽  
Ryan P. Goepfert ◽  
Jonathan L. Curry ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Positive Sentinel Lymph Node ◽  
Tumor Thickness ◽  
Conjunctival Melanoma ◽  
Worse Prognosis

Primary tumor thickness as a risk factor for contralateral cervical metastases in T1/T2 oral tongue squamous cell carcinoma

2009 ◽  
Vol 119 (5) ◽  
pp. 883-888 ◽  
Author(s):  
Carol M. Bier-Laning ◽  
Ramon Durazo-Arvizu ◽  
Kamil Muzaffar ◽  
Guy J. Petruzzelli
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Tumor Thickness ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue ◽  
Cervical Metastases
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