scholarly journals 876 Disorders of the Brain Revealed by Magnetic Resonance Imaging (MRI) in Infants with Severe Congenital Cytomegaly

2010 ◽  
Vol 68 ◽  
pp. 440-440
Author(s):  
B Milewska-Bobula ◽  
B Lipka ◽  
J Zebrowska ◽  
E Jurkiewicz ◽  
I Pakula-Kosciesza ◽  
...  
2021 ◽  
Vol 1 (4) ◽  
pp. 416-428
Author(s):  
Vijay Anant Athavale ◽  

Gadolinium (Gd) is a based contrast agent is used for Magnetic Resonance Imaging (MRI). In India, gadobutrolhas been is approved for MRI of the Central Nervous System (CNS), liver, kidneys, and breast. It has been noted in several studies that the accumulation of gadolinium occurs in different structures in the brain. Patients with Multiple Sclerosis (MS) are regularly followed up with MRI scans and MRI with contrast enhancement is the most common method of distinguishing new-onset pathological changes. Developments in technology and methods in artificial intelligence have shown that there is reason to map out the X-ray technician’s work with examinations and medicines administered to patients may be altered to prevent the accumulation of gadolinium.


2018 ◽  
Vol 33 (6) ◽  
pp. 428-431 ◽  
Author(s):  
Suvasini Sharma ◽  
Preeti Singh ◽  
Erika Fernandez-Vizarra ◽  
Massimo Zeviani ◽  
Marjo S. Van der Knaap ◽  
...  

A 5-year-old Indian boy presented with subacute onset regression of milestones associated with seizures and spasticity. The symptoms started after an attack of measles. The magnetic resonance imaging (MRI) of the brain showed cavitating leukodystrophy with posterior predominance. Molecular analysis of the APOPT1 gene, a recently described gene associated with mitochondrial leukodystrophy, showed the patient to be homozygous for a 12.82-kilobase deletion, including coding exon 3. Deletion of exon 3 produces a frameshift, predicting the translation of a truncated protein (p.Glu121Valfs*4). The patient was started on mitochondrial cocktail regimen of thiamine, riboflavin, coenzyme Q and carnitine. Although he initially showed some improvement, he died 6 months after the onset of his illness.


2011 ◽  
Vol 68 (10) ◽  
pp. 842-845 ◽  
Author(s):  
Jasna Jevdjic ◽  
Maja Surbatovic ◽  
Svetlana Drakulic-Miletic ◽  
Filip Zunic

Backround/Aim. Sedation is necessary in children undergoing magnetic resonance imaging (MRI) to ensure motionless. The success of sedation is typically measured by two factors: safety (lack of adverse events) and effectiveness of the procedure (successful completion of the diagnostic examination). Propofol is frequently used to induce deep sedation in children. However, increased doses of propofol may lead to oversedation and respiratory depression. The aim of the study was to investigate sedation in children using propofol with midazolam in regard to efficacy, adverse events and time to return to presedation functional status. Methods. We investigated 24 children prospectively. Sedation was introduced with a single bolus of intravenous (iv) midazolam 0.1 mg/kg followed by repeated small iv boluses of propofol until sufficient depth of sedation was obtained. The outcome of sedation was measured by the induction time, sedation time, need for additional sedation, respiratory events, cardiovascular events and sedation failure. Results. Median age of children was 4.72 ? 3.06 (1.1-12.3) years and their body weight was 21.3 ? 11.9 (11-60) kg. Average propofol bolus dose for induction was 1.76 ? 0.9 (0.5-4) mg/kg. The induction time was 8.88 ? 2.92 (5-15) min, and sedation time 28.39 ? 8.42 (20-50) min. Additional sedation was necessary in 3 (12.5%) patients. Unsucesfull sedation or significant adverse events were not observed. Conclusion. The presented sedation technique for children undergoing ambulatory MRI of the brain is safe and adequate. This sedation regiment provides short induction time, fast recovery, stable cardiorespiratory conditions and rarely demans additional sedation.


2011 ◽  
Vol 50 (12) ◽  
pp. 1134-1139 ◽  
Author(s):  
Phillipp Fridolin Streibert ◽  
Werner Piroth ◽  
Michael Mansour ◽  
Patrick Haage ◽  
Thorsten Langer ◽  
...  

The aim of this study was to evaluate the frequency of abnormal findings in magnetic resonance imaging (MRI) in children with headache, the clinical relevance of these findings, and whether more sophisticated technologies also result in more relevant abnormal findings. The MRIs of 1004 children with age ranging from 1 to 17 years were retrospectively analyzed. Children who were investigated with established sequences (n = 419) were compared with those examined with state-of-the-art MRI acquisition technology (n = 585). In 216/1004 investigations, MRI was performed because of headache (74/216 with established sequences, 142/216 with state-of-the-art acquisition technology). In 114/216 (52.8%) patients with headache, the MRI was abnormal with relevant findings in 23/114 patients and findings without clinical relevance in 91/114 children. A higher incidence of abnormal findings than in previous reports was found but there was only limited clinical gain of information using modern sequences in children with headache.


2005 ◽  
Vol 18 (5-6) ◽  
pp. 581-588
Author(s):  
I. Tsitouridis ◽  
P. Papapostolou ◽  
J. Rudolf ◽  
K. Natsis ◽  
L. Tarazi ◽  
...  

Magnetic Resonance Imaging (MRI) study of the brain and Magnetic Resonance Venography (MRV) offer major advantages in evaluating patients suspected of having dural sinus thrombosis. Since 2002, we have examined 49 patients in our department with definite dural sinus thrombosis. MRI and MRV revealed the thrombosis of the dural sinus, and the underlying cause in most patients. There is consensus in the literature that MRI scanning in combination with MRV is the method of choice for evaluating dural sinus thrombosis, and this is also the end result of our study. We also compared the 3D-TOF technique and 2D-PC technique for MRV examination and found that the 3D-TOF technique is clearly the method of choice.


2005 ◽  
Vol 46 (1) ◽  
pp. 101-103 ◽  
Author(s):  
A. Yeşildağ ◽  
A. Ayata ◽  
B. Baykal ◽  
M. Koroglu ◽  
H. Yıldız ◽  
...  

Methylmalonic acidemia (MMA) is an inborn disorder of amino acid metabolism, often presenting with neurological symptoms. We present the results of magnetic resonance imaging (MRI) and diffusion‐weighted imaging (DWI) of the brain in a 16‐month‐old male patient with classic neurological and laboratory findings for MMA. MRI demonstrated the hyperintensity within globi pallidi both on T2‐weighted image and DWI during the acute episode of metabolic acidosis.


1987 ◽  
Vol 32 (8) ◽  
pp. 702-712 ◽  
Author(s):  
P. Conlon ◽  
M.R. Trimble

Magnetic resonance imaging (MRI) is a relatively new radiological technique that may be useful in the study of psychiatric illness. MRI gives detailed structural information about the brain and also allows quantification of functional change. Current areas of study relevant to psychiatry include: schizophrenia, dementia, epilepsy and, to a lesser extent, alcohol and affective disorders. The authors review the basic principles of MRI, discuss the recent application to psychiatry, indicate its potential advantages and comment on the current limitations of this imaging modality.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hui Guo ◽  
Wenya Liu ◽  
Jian Wang ◽  
Yan Xing

AbstractAlveolar echinococcus (AE) is a severe health problem in endemic areas. In recent years, the incidence of this disease in China has been increasing. The study was designed to illustrate the multi-slice computed tomography (MSCT) and magnetic resonance imaging (MRI) features of extrahepatic AE. A cohort of 33 patients who suffered from extrahepatic AE was enrolled consecutively from January 2012 to December 2017. The MSCT and MRI features of extrahepatic AE were recorded and analyzed by experienced radiologists. All cases secondary to hepatic AE, except two primary extrahepatic AE, were found in this study. Locations of extrahepatic AE included 19 (57.6%) lung, 10 (30.3%) adrenal gland, 9 (27.3%) brain, 5 (15.2%) peritoneal cavity, 5 (15.2%) spleen, 4 (12.1%) diaphragm, 3 (9.1%) kidney, 3 (9.1%) retroperitoneal, and 2 (6.1%) vertebra; Involvement of 1 (3.0%) heart, 1 (3.0%) mediastinum, 1 (3.0%) muscle, and 1 (3.0%) pancreas was rare. AE of the lung usually appeared as irregular and scattered nodules with small vacuoles or cavities inside and peripheral distribution. Multiple cerebral nodules with calcification and surrounding edema were the most common features seen in brain AE. Adrenal gland AE presented as plaques containing different sizes of hypodense areas and different amounts of calcification. Injection of contrast medium showed no enhancement of lesions except in the brain. MSCT and MRI are reliable imaging methods for the diagnosis of extrahepatic AE. When one AE patient is clinically confirmed, MSCT scan from the chest to the abdomen should be performed to exclude other organs AE.


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