Vasovagal reactions in volunteer blood donors: Analyzing the predictive power of the medical fears survey

2000 ◽  
Vol 7 (1) ◽  
pp. 62-72 ◽  
Author(s):  
Jennifer S. Labus ◽  
Christopher R. France ◽  
Brandie K. Taylor
1999 ◽  
Vol 18 (4) ◽  
pp. 403-409 ◽  
Author(s):  
Lori A. Sauer ◽  
Christopher R. France

Transfusion ◽  
1999 ◽  
Vol 39 (3) ◽  
pp. 316-320 ◽  
Author(s):  
Jonathan J. Trouern-Trend ◽  
Ritchard G. Cable ◽  
Stanley J. Badon ◽  
Bruce H. Newman ◽  
Mark A. Popovsky

2005 ◽  
Vol 15 (5) ◽  
pp. 389-394 ◽  
Author(s):  
E. K. Zervou ◽  
K. Ziciadis ◽  
F. Karabini ◽  
E. Xanthi ◽  
E. Chrisostomou ◽  
...  

Transfusion ◽  
2011 ◽  
Vol 51 (10) ◽  
pp. 2061-2063 ◽  
Author(s):  
Bruce H. Newman ◽  
Barry A. Siegfried

Author(s):  
Vijayalakshmi Kuttath ◽  
Harikumaran Nair ◽  
Muraleedharan Nair

Introduction: A crucial component of the effort to meet the growing demand for blood is the recruitment and retention of young novice blood donors. Reducing postdonation syncopal reactions could have a beneficial impact on donor convenience, safety, and desire to donate again. Aim: To evaluate the effectiveness of predonation hydration over standard blood donation in the prevention or decrease in severity of postdonation Vasovagal Reactions (VVR) in hydrated blood donors in comparison with the non hydrated group. Materials and Methods: The randomised controlled trial was conducted on 953 first time voluntary blood donors. Donors in the intervention arm drank 250 mL water 30 minutes before blood donation, while those in the control group did not receive any intervention. Blood was collected by standard protocol. Outcome, VVR, if present was graded as mild, moderate, and severe. Analysis of results were done using Statistical Package for the Social Sciences (SPSS) version 16.0. A sensitivity analysis was also done to consider the dropouts from the study. Results: A total of 900 participants were included in the study, of which 443 were controls and 457 were cases. An effect size of 6.1%, a Relative Risk (RR) of 0.54 {95% Confidence Interval (CI)=0.36-0.81} and a risk reduction of 45% was arrived at, pointing to a protective role for predonation hydration in preventing VVR. There was a significant reduction in the severity of VVR in the predonation hydration group compared to the standard blood donation group (p-value=0.002). The protective effect of hydration on decreasing the occurrence and severity of VVR had statistical support in males in the moderate and severe grades (p-value=0.017). A similar statistical significance was not established in females (p-value=0.173). Sensitivity analysis did not reveal a difference in the statistical significance of variables between compared groups. Conclusion: Predonation hydration was found to be effective in preventing and decreasing the severity of VVR in novice blood donors.


2019 ◽  
Vol 15 (2) ◽  
pp. 253-260
Author(s):  
Karan Kumar ◽  
Suchet Sachdev ◽  
Neelam Marwaha ◽  
Ratti Ram Sharma

2013 ◽  
Vol 3 (6) ◽  
pp. 459-463 ◽  
Author(s):  
S Mangwana

Background: Hemovigilance like quality systems and audits have become an integral part of Blood Transfusion Services in the developed countries and has contributed greatly to its development. Hemovigilance begins with donors and must enable the collection of information on reactions occurring during the donation of blood, selections of donors and to prevent such incidents. The aim of study was to help identify the trends of adverse events , occurring in blood donors at a tertiary-care hospital, to recommend best practices to improve donor care and safety Materials and Methods: This record-based study was conducted on all adverse events related to allogenic whole blood donations performed over 24 months. All whole blood donations were analyzed. All adverse events occurring during or at the end of the donation were noted using a standardized format and analyzed determining significance at p<0.05. Results: Overall rate was 0.3% with vasovagal reactions constituting 82%, and 18% mild syncopal reactions (p<0.001). Immediate vasovagal reaction with injury was very rare (0.007%). Vasovagal reactions showed a significant association with young age, female gender, first time donation status. Mean age of persons recording adverse effects was 30.23 ± 7.49 years as compared to those without adverse effects, 31.14 ± 8.56 years. Conclusion: Donor safety is an essential perquisite to increase voluntary blood donation. AE analysis helps in identifying the blood donors at risk of AE, applying appropriate motivational strategies, predonation counseling, care during and after donation, developing guidelines and hemovigilance programme in countries with limited resources. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8993   Journal of Pathology of Nepal (2013) Vol. 3, 459-463


Transfusion ◽  
2011 ◽  
Vol 52 (5) ◽  
pp. 1070-1078 ◽  
Author(s):  
Thelma T. Gonçalez ◽  
Ester C. Sabino ◽  
Karen S. Schlumpf ◽  
David J. Wright ◽  
Silvana Leao ◽  
...  

Transfusion ◽  
1980 ◽  
Vol 20 (6) ◽  
pp. 679-683 ◽  
Author(s):  
H Ogata ◽  
N Iinuma ◽  
K Nagashima ◽  
T Akabane

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