scholarly journals Donor Hemovigilance Programme in managing Blood Transfusion Needs: Complications of Whole Blood Donation

2013 ◽  
Vol 3 (6) ◽  
pp. 459-463 ◽  
Author(s):  
S Mangwana
Keyword(s):  
Blood Transfusion ◽  
Adverse Effects ◽  
Adverse Events ◽  
Whole Blood ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Care Hospital ◽  
Blood Donations ◽  
Vasovagal Reactions

Background: Hemovigilance like quality systems and audits have become an integral part of Blood Transfusion Services in the developed countries and has contributed greatly to its development. Hemovigilance begins with donors and must enable the collection of information on reactions occurring during the donation of blood, selections of donors and to prevent such incidents. The aim of study was to help identify the trends of adverse events , occurring in blood donors at a tertiary-care hospital, to recommend best practices to improve donor care and safety Materials and Methods: This record-based study was conducted on all adverse events related to allogenic whole blood donations performed over 24 months. All whole blood donations were analyzed. All adverse events occurring during or at the end of the donation were noted using a standardized format and analyzed determining significance at p<0.05. Results: Overall rate was 0.3% with vasovagal reactions constituting 82%, and 18% mild syncopal reactions (p<0.001). Immediate vasovagal reaction with injury was very rare (0.007%). Vasovagal reactions showed a significant association with young age, female gender, first time donation status. Mean age of persons recording adverse effects was 30.23 ± 7.49 years as compared to those without adverse effects, 31.14 ± 8.56 years. Conclusion: Donor safety is an essential perquisite to increase voluntary blood donation. AE analysis helps in identifying the blood donors at risk of AE, applying appropriate motivational strategies, predonation counseling, care during and after donation, developing guidelines and hemovigilance programme in countries with limited resources. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8993   Journal of Pathology of Nepal (2013) Vol. 3, 459-463

scholarly journals A study to evaluate the demographic profile of voluntary and replacement blood donors at tertiary care hospital in Mumbai, India: a 5-year retrospective comparative analysis

2021 ◽  
Vol 9 (3) ◽  
pp. 866
Author(s):  
Khaneta Parveen ◽  
Abdul F. Khan ◽  
Abdul S. Khan
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Care Hospital ◽  
Demographic Profile ◽  
Medical College ◽  
Donor Type ◽  
Males And Females ◽  
And Gender

Background: Blood donor base is the foundation of any blood transfusion system. Donor screening plays an important role in ensuring the safety of the blood supply.1 This study was undertaken with the aim to screen the blood donor’s demographic profile as male, female voluntary and replacement blood donors and to estimate seroprevalence of HIV, HBV, HCV and VDRL transmissible by blood transfusion in voluntary and replacement male and female blood donors during the last 5 year period.Methods: The present study was conducted over a period of 5 years (2001-2005) and involved 1,53,020 blood donors including both (voluntary, replacement males and females) who were thoroughly screened and selected for blood donation in blood bank at Departments of Pathology, Seth GS Medical College and KEM hospital, Mumbai. We determine among blood donors by their donor type (voluntary and replacement type) and gender wise.Results: The total number of blood donors in five years period was 1,53,020 (100%). Maximum number of voluntary  blood donors 1,00,316 (65.55%), followed by replacement blood donors 52,704 (34.33%).The overwhelming majority of donors in entire 5 years period was of male, comprising 1,36,195 (89.0%), while the female donors comprised of 16825 (10.99%).Conclusions: The maximum number of donors are voluntary males (55.69%) followed by replacement males (33.30%). Our results indicate that the number of female blood donors were less in comparison to male blood donors, so proper health education is required for female blood donors.

scholarly journals Analysis of Blood Donor Deferral in a Tertiary Care Hospital

2020 ◽  
Vol 10 (2) ◽  
pp. 373-376
Author(s):  
Farida Parvin ◽  
Daanish Arefin Biswas ◽  
Bepasha Naznin ◽  
Tamanna Afroz ◽  
Mohammad Ali ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Medical Officer ◽  
Uncontrolled Hypertension ◽  
Care Hospital ◽  
Safe Blood ◽  
Donor Deferral

Introduction: Selection of proper donor according to stringent selection criteria is the prerequisite for safe blood transfusion practice. It is widely known that a large number of blood donors are deferred for different reasons. Objective: The aim of present study is to evaluate the incidence and different reasons of blood donor deferral in atertiary care hospital. Methodology: This retrospective cross-sectional study was carried out in Transfusion Medicine and Clinical Haematology Department of BIRDEM General Hospital, Dhaka, during the period from July 2016 to June 2017.The blood donor of either sex attending the mentioned department were selected purposively and categorized into four groups according to their age for this study. Donors were selected and deferred by medical officer according to national guideline. Deferred blood donors were recorded in register book and were analyzed retrospectively. Results: In current study, 1152 blood donor (8.8%) were deferred attending for allogeneic blood donation during the study period. Out of 13082 registered blood donor 11961were male (91.43%) and 1121 were female (8.57%) and deferral rate was 2.37 times more in female. Majority of the deferred donors (55.38%) were under the age of 40 where 26.82% were in between 40-49 years and 17.8% were in the range of 50 years and above. Age range of highest deferred donors (32.20%) was between 30-39 years. The number of temporary and permanent deferral were 836 (72.57 %) and 316 (27.43%) respectively. Anaemia (33.01%), underweight (21.53%) and hypotension (17.34%) were the most common reason of temporary deferral. Chronic uncontrolled hypertension (42.4%), donors with medication (16.77%) and asthma (15.18%) was the most common cause of permanent deferral. Conclusion: The deferral rate was low and most of the deferred donors were young adult. Temporary deferred donors were higher than permanent deferred donors. The most common reasons for temporary deferral were anemia, underweight and hypotension. Permanent deferral causes were chronic uncontrolled hypertension, donors on medication for various reason and asthma. Donors should be informed with a clear message on their deferral status. It is important to determine the rate and causes of donor deferral for the safety of blood transfusion and to guide the recruitment efforts for safe blood transfusion and to avoid the permanent loss of blood donors. Northern International Medical College Journal Vol.10 (2) Jan 2019: 373-376

scholarly journals Seroprevalence and trends of transfusion transmitted infections in blood donors of rural tertiary care hospital blood bank: a 3 year retrospective study in Chamba (HP)

2018 ◽  
Vol 5 (6) ◽  
pp. 2453
Author(s):  
Ishan Arora ◽  
Shairoly Singh ◽  
Shireen Singh
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Blood Bank ◽  
Care Hospital ◽  
Total Blood ◽  
Medical College ◽  
Disease Pattern ◽  
Donor Population

Background: Timely transfusion of blood saves millions of lives, but unsafe transfusion practices puts millions of people at risk of transfusion transmissible infections (TTIs). Blood transfusion carries the risk of transfusion-transmissible infections including human immunodeficiency virus (HIVI&II), hepatitis B virus (HBV), hepatitis C virus (HCV), malaria and syphilis. With every unit of blood there are 1% chances of transfusion associated diseases.Methods: This study was conducted over a period of 3 years (1stJanuary 2015-31st December 2017) at hospital blood bank of Pt. Jawaharlal Nehru Government Medical College, Chamba (H.P). The study was conducted on both voluntary and replacement blood donors who came to our blood bank and voluntary blood donation camps in and around Chamba. Statistical analysis used. Collected data was analyzed using appropriate statistical softwares such as EPI-INFO and MS-Excel.Results: In our study, we observed a total of 2616 donors over a period of 3 years. In the present study, 847 (32.37%) were voluntary donors and 1769 (67.62%) were replacement donors. Out of 2616 blood samples, 8 were HBsAg positive, 1 HCV positive.Conclusions: Our study shows that the number of blood donors is increasing every year. In our study, the seroprevalence of HBsAg was 0.3% and Hep C was 0.03% in total blood donors. The knowledge of current infectious disease pattern and trends in donor population can help in planning of future blood transfusion related health challenges. 

Increasing Seroprevalence of Hepatitis C Virus among Blood Donors - A 3 Year Study in North India

2021 ◽  
Vol 8 (07) ◽  
pp. 379-383
Author(s):  
Jagjeewan Ram ◽  
Namrata Nigam ◽  
Aparna Singh ◽  
Lubna Khan
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Tertiary Care ◽  
North India ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
Hepatitis C Infection ◽  
Case Volume

BACKGROUND The primary aspect of blood transfusion lies in the availability of blood and blood components which are tested and reported negative for transfusion transmitted infections (TTI’s). The increased seroprevalence of TTI’s indicate their prevalence in general public. The study was conducted to analyse the increasing seroprevalence of hepatitis C virus (HCV) over a period of 3 years. The objectives of the study determine the seroprevalence of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) among the voluntary blood donors at a tertiary care hospital & associated blood bank. METHODS This cross-sectional study was done at the Department of Transfusion Medicine, GSVM Medical College, Kanpur, Uttar Pradesh, over a period of 3 years from July 2017 to June 2020. The samples collected were screened by enzyme-linked immunosorbent assay (ELISA) tests. RESULTS A total of 69561 blood units were collected during this 3-year study from July 2017 to June 2020. Of all the blood bags screened, the highest prevalence was seen for HBV followed by HCV and HIV. 949 (1.4 %) were reactive for HBV, 75 (0.1 %) were reactive for HIV and 332 (0.5 %) were reactive for HCV. The results show a remarkable increase in the seropositivity for hepatitis C infection. CONCLUSIONS The seroprevalence of HCV has seen an increase in case load over the years as compared to HBV and HIV. This increase in case volume is indicative of impending liver diseases progressing to chronic stage over the years. Thus, it is imperative to create awareness in the general population to help reduce the risk factors responsible for HCV infection. KEYWORDS Blood Transfusion, Voluntary Donors, HCV, HBV, HIV, Seroprevalence, Transfusion Transmitted Infections (TTI’s)

scholarly journals Pattern of utilization of blood and blood components in obstetrics at tertiary care hospital

2017 ◽  
Vol 6 (10) ◽  
pp. 4671
Author(s):  
Vidyadhar Bangal Bangal ◽  
Satyajit P. Gavhane ◽  
Kunal H. Aher ◽  
Dhruval K. Bhavsar ◽  
Priyanka R. Verma ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donation ◽  
Tertiary Care ◽  
Severe Anaemia ◽  
Blood Bank ◽  
Care Hospital ◽  
Obstetric Haemorrhage ◽  
Obstetric Emergencies ◽  
The Common ◽  
Health Institutions

Background: Obstetric emergencies occur suddenly and unexpectedly. Blood transfusion becomes one of the live saving measures in such situations. Severe anaemia due to nutritional deficiency, obstetric haemorrhage either during pregnancy, labour or in postpartum period are the commonest indications for blood transfusion worldwide. Blood bank services play important role in saving lives in obstetric emergencies. Health institutions must carry out internal blood transfusion audits to reassure optimal and judicious use of blood and blood components.Methods: Analysis of 755 Obstetric patients requiring blood transfusion in eighteen months period was done to find out the incidence and indications for blood transfusion at tertiary care hospital.Results: Overall, 5.33% of obstetric admissions required transfusion of blood or its components. Severe anaemia (36.55%), accidental haemorrhage (20.92%), postpartum haemorrhage (8.34%), placenta praevia (5.03%) and caesarean section (10.33%) were the common indications for blood transfusion. In more than 65% cases, two or three unit of blood were transfused. In majority of cases (96%) components were used.Conclusions: Blood transfusion helped to save many lives in the present study. Severe anaemia and obstetric haemorrhage of varied aetiology were the common indications for blood transfusion. Component therapy helped to correct specific deficiency. Voluntary blood donation should be encouraged in the younger generation to keep adequate stock of blood in blood bank for emergency use. Preventive measures like improving dietary iron intake and prophylactic iron therapy will go a long way in reducing the need for blood transfusion in Obstetrics.

scholarly journals Donor awareness: key to successful voluntary blood donation

F1000Research ◽  
2012 ◽  
Vol 1 ◽  
pp. 29 ◽  
Author(s):  
Rateesh Sareen ◽  
Gajendra N Gupta ◽  
Akanksha Dutt
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Tertiary Hospital ◽  
Statistical Technique ◽  
Study Data ◽  
Blood Bank ◽  
Western India ◽  
Care Hospital ◽  
Proactive Measures

Context: The current regulatory requirements for donor eligibility pose a challenge to blood centers in recruitment of voluntary blood donors, particularly in a developing country like India where awareness of the general population is low and myths about blood donation are prevalent. This study evaluates the reasons and rates of donor deferral in a tertiary hospital-based blood bank in western India.Aim: To find rates and reasons for deferral of voluntary blood donors in a city in western India.Settings and design: A retrospective study was done on blood donors during a 3-month period. Data collection was done by electronic records of blood donors.Materials and Methods: The study was conducted retrospectively at a tertiary care hospital in western India. All those who donated whole blood between 1st January 2011 and 31st March 2011 were included in the study. Data was collected using local blood bank software.Statistical analysis used: No statistical technique used as it is a data article.Results: 60.5% of donors were young, below 30 years of age. Donors were predominantly male (91.6%). Voluntary donors comprised 88% of the donors. Total deferral rate was 22.36%, with 17.29% permanent deferrals and 82.71% temporary deferrals. Main reasons for deferral were anemia 39.42%, low body weight 14.29%, hypertension 10.73%, age below 18 years 10.73% and history of medication 6.09%. The common causes of deferral between our study and other similar studies are the same.Conclusion: We concluded that majority of the donor population belongs to 18–30-year-old age group. This is encouraging with a voluntary blood donation initiative. Donor self exclusion and strict donor selection criteria application should be addressed by more proactive measures to make blood donation a safe and pleasurable experience.

scholarly journals A Comparative Study of Storage Related Haematological Changes in Whole Blood and PRBC in Blood Bank of a Tertiary Care Hospital

2020 ◽  
Vol 9 (2) ◽  
pp. 1-7
Author(s):  
Pratibha Shirvastava ◽  
Shyamoli Dutta
Keyword(s):  
Blood Transfusion ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Whole Blood ◽  
Tertiary Care ◽  
Blood Bank ◽  
Clotting Factor ◽  
Research Centre ◽  
Care Hospital ◽  
Haematological Changes

Background: Blood transfusion is very common in present era. Now day’s whole blood transfusion is common but also the blood product like red blood cell, white blood cell, platelets, clotting factor, plasma can be done .the aim of study to know the storage related changes in whole blood, packed red blood cell. Subjects and Methods: In our institution we have selected 100 voluntary blood donors sample in blood bank of Teerthankar Mahaveer medical college and research centre, Moradabad up to 12 month. Results: The store blood is Followed up to 35th days .during regular interval 1st, 7th, 14th, 21st, 28th and 35th day, in the blood there is significant change in and all other component in all sample. Conclusion: In the case of storage of blood in blood bank. As the number day of store is more the haematological changes is more significant.

The Effect of Repeated Blood Donations on the Iron Status of Iranian Blood Donors Attending the Iranian Blood Transfusion Organization

2006 ◽  
Vol 76 (3) ◽  
pp. 132-137 ◽  
Author(s):  
Mahmoud Djalali ◽  
Tirang R. Neyestani ◽  
Jamil Bateni ◽  
Fereydoun Siassi
Keyword(s):  
Iron Deficiency ◽  
Blood Transfusion ◽  
Serum Ferritin ◽  
Blood Donors ◽  
Blood Donation ◽  
Iron Status ◽  
Iron Loss ◽  
Healthy Controls ◽  
Blood Donations ◽  
Group Frequency

Objective: Blood donation leads to substantial iron loss, as about 0.5 mg iron is lost per each milliliter of blood donated. If not compensated for efficiently, the iron loss may eventually lead to anemia, though non-anemic iron deficiency per se may be problematic. The aim of this study was to evaluate the effects of blood donation, and its frequency over a year’s time, on iron status of Iranian male blood donors attended blood transfusion stations of the Iranian Blood Transfusion Organization (IBTO). Design and setting: A cross-sectional, descriptive, and analytic study was conducted. 91 male volunteer blood donors aged from 20 to 50 years attending three IBTO stations located in central areas of Tehran, and 63 apparently healthy controls that were matched for age, gender, monthly income, height, and weight, were included in the study. Blood donors were divided into 4 groups according to the frequency of blood donation per year; i.e. 1, 2, 3, and 4 with 20, 30, 26, and 15 persons in each group, respectively. Just before blood donation, 10 mL venous blood sample was taken and divided into heparinized and non-heparinized tubes for determination of hemoglobin (Hb), hematocrit (Hct), serum iron (SI), total iron binding capacity (TIBC), ferritin, transferrin saturation (TS), and mean corpuscular hemoglobin concentration (MCHC). Dietary assessment was also done using 3 different questionnaires; i.e. general health, food frequency, and 24hr recall. Results: The levels of Hb, Hct, and iron status indices were all significantly lower in the subjects than in controls and a gradual but significant decrease in iron status indices in each time of blood donation was found. Serum ferritin showed significant correlations with age (r = 0.33, p < 0.001) and body-mass index (BMI) (r = 0.26, p = 0.03) only in the control group. Frequency of blood donation per year was also inversely correlated with Hb (r = -0.67, p < 0.001), Hct (r = -0.65, p < 0.001), MCHC (r = -0.56, p < 0.001), serum ferritin (r = -0.38, p < 0.001), SI (r = -0.62, p < 0.001), and TS (r = -0.61, p < 0.001), but was directly correlated with TIBC (r = 0.56, p < 0.001). Interestingly in blood donors, but not in healthy controls, serum ferritin levels showed weak but statistically significant correlations with daily intake of iron (r = 0.17, p < 0.05) and energy (r = 0.20, p = 0.03). Conclusion: Though repeated blood donations might diminish iron status, it could be safe to donate 2–3 U/year without an appreciable incidence of iron deficiency, provided that the pre-donation Hb and ferritin values are ≥ 14.7 g/dL and 58.9 μg/L, respectively. The male volunteers with Hb ≥ 14.2 g/dL and serum ferritin ≥ 57.2 μg/L could donate 1–2 U/year and those with Hb ≥ 13.1 g/dL and serum ferritin ≥ 35.3 μg/L could donate just once a year. Volunteers who undergo (repeated) blood donation should receive special nutritional care, especially in terms of iron and energy.

Sign in / Sign up

Export Citation Format

Share Document