scholarly journals Effects of a Low-Fat, High-Fiber Diet and Exercise Program on Breast Cancer Risk Factors In Vivo and Tumor Cell Growth and Apoptosis In Vitro

2006 ◽  
Vol 55 (1) ◽  
pp. 28-34 ◽  
Author(s):  
R. James Barnard ◽  
Jenny Hong Gonzalez ◽  
Maud E. Liva ◽  
Tung H. Ngo
Keyword(s):  
Exercise Program ◽  
Tumor Cell Growth ◽  
Cancer Risk Factors ◽  
High Fiber ◽  
Fiber Diet ◽  
Diet And Exercise ◽  
Breast Cancer Risk Factors ◽  
High Fiber Diet

scholarly journals In vitro dry matter disappearance using roe deer inocula from summer and winter

Rangifer ◽  
1993 ◽  
Vol 13 (4) ◽  
pp. 143 ◽  
Author(s):  
Øystein Holand
Keyword(s):  
Dry Matter ◽  
Roe Deer ◽  
Capreolus Capreolus ◽  
High Fiber ◽  
Ruminal Microorganisms ◽  
Fiber Diet ◽  
Significant Difference ◽  
Laboratory Procedures ◽  
High Fiber Diet

In vitro dry matter disappearance (IVDMD) of 12 forages were determined using ruminai inocula from 10 European roe deer (Capreolus capreolus L.) collected in summer and winter. There was significant difference in the ability of winter and summer inocula to digest winter and summer forages respectively. Each of the 6 summer forages had a significantly higher IVDMD in ruminal inocula of animals collected in summer versus winter. However, no significant difference in IVDMD of winter versus summer inocula was observed for each of the 6 winter forages. These results suggest adaption, although limited, by ruminal microorganisms in roe deer to winter forages or a potential problem in standard in vitro laboratory procedures when using animals on a high-fiber diet as inocula donors.

scholarly journals Analyzing Serum-Stimulated Prostate Cancer Cell Lines After Low-Fat, High-Fiber Diet and Exercise Intervention

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Sherry Soliman ◽  
William J. Aronson ◽  
R. James Barnard
Keyword(s):  
Exercise Intervention ◽  
P53 Protein ◽  
Lncap Cells ◽  
Low Fat ◽  
High Fiber ◽  
Fiber Diet ◽  
Diet And Exercise ◽  
Igf I ◽  
Diet And Exercise Intervention ◽  
High Fiber Diet

Serum from men undergoing a low-fat, high-fiber diet and exercise intervention has previously been shown to decrease growth and increase apoptosis in serum-stimulated, androgen-dependent LNCaP cells associated with a reduction in serum IGF-I. Here we sought to determine the underlying mechanisms for these anticancer effects. Again, the intervention slowed growth and increased apoptosis in LNCaP cells; responses that were eliminated when IGF-I was added back to the post-intervention samples. The p53 protein content was increased and NFκB activation reduced in the post serum-stimulated LNCaP cells. Similar results were observed when the IGF-I receptor was blocked in the pre-intervention serum. In androgen-independent PC-3 cells, growth was reduced while none of the other factors were changed by the intervention. We conclude that diet and exercise intervention might help prevent clinical PCa as well as aid in the treatment of PCa during the early stages of development.

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