Feedback Mechanisms Including Real-Time Electronic Alerts to Achieve Near 100% Timely Prophylactic Antibiotic Administration in Surgical Cases

2010 ◽  
Vol 111 (5) ◽  
pp. 1293-1300 ◽  
Author(s):  
Bala G. Nair ◽  
Shu-Fang Newman ◽  
Gene N. Peterson ◽  
Wei-Ying Wu ◽  
Howard A. Schwid
Keyword(s):  
Real Time ◽  
Prophylactic Antibiotic ◽  
Antibiotic Administration ◽  
Feedback Mechanisms ◽  
Electronic Alerts

Perioperative Cefovecin to Reduce the Incidence of Urinary Tract Infection in Dogs Undergoing Hemilaminectomy

2016 ◽  
Vol 52 (5) ◽  
pp. 297-304 ◽  
Author(s):  
Joseph D. Palamara ◽  
Jennifer J. Bonczynski ◽  
Jason M. Berg ◽  
Philip J. Bergman
Keyword(s):  
Urinary Tract ◽  
Urine Culture ◽  
Prophylactic Antibiotic ◽  
Neurologic Deficit ◽  
Antibiotic Administration ◽  
Type I ◽  
Additional Risk ◽  
Neurologic Recovery ◽  
Tract Infections ◽  
Disc Extrusion

ABSTRACT The prevalence of urinary tract infections (UTIs) in dogs with Type I intervertebral disc extrusion has been reported as high as 38% within 6 wk of surgery. Proper treatment of a UTI is important with myelopathy because it is a risk factor for persistent infection and reinfection in dogs. The study authors' investigated the incidence of UTIs in dogs having received either cefovecin or cefazolin as a preoperative prophylactic antibiotic for thoracolumbar hemilaminectomy. Thirty-nine dogs were retrospectively identified and assigned to groups based on preoperative antibiotic administration and postoperative urinary tract management. Urinalysis and urine culture performed preoperatively, at 2 wk, and at 6 wk, were reviewed to determine the incidence of UTIs. Urinary tract management, grade of neurologic deficit, time to ambulation, and time to voluntary urination were identified to evaluate for additional risk factors. No significant prevalence of UTI incidence was appreciated between the cefovecin and cefazolin groups. Patients with higher grades of neurologic deficit and that took longer to regain ambulation and voluntary urination were at significantly greater risk for UTIs throughout the postoperative period. This study reemphasizes the importance of continued surveillance for UTIs in patients with prolonged neurologic recovery.

Group A Streptococcus Carriage in an Alabama Child-Care Center Following a Fatal Invasive Case

PEDIATRICS ◽  
1994 ◽  
Vol 94 (6) ◽  
pp. 1030-1030
Author(s):  
Michael M. Engelgau ◽  
John M. Horan ◽  
Charles H. Woernle ◽  
Banjamin Schwartz ◽  
Richard R. Facklam ◽  
...  
Keyword(s):  
Risk Factors ◽  
Child Care ◽  
Group A Streptococcus ◽  
Care Center ◽  
Fatal Case ◽  
Prophylactic Antibiotic ◽  
Child Care Center ◽  
Antibiotic Administration ◽  
Group A

Carriage of the GAS strain was common and widespread following a single fatal case of invasive GAS disease at the child-care center. Risk factors for GAS T-1 carriage did not identify all carriers. Our findings suggest that widespread culturing is needed to identify all potential carriers. The role of prophylactic antibiotic administration in preventing secondary cases could not be determined.

Effect of penicillin allergy on prophylactic antibiotic administration in the parturient undergoing cesarean delivery

2020 ◽  
Author(s):  
Samantha M. Lange ◽  
Emily E. Sharpe ◽  
Dana N. Hertzfeldt ◽  
Darrell R. Schroeder ◽  
Hans P. Sviggum
Keyword(s):  
Cesarean Delivery ◽  
Prophylactic Antibiotic ◽  
Penicillin Allergy ◽  
Antibiotic Administration

scholarly journals Assessment of antibiotic prophylaxis in surgical patients at the Gaffrée e Guinle University Hospital.

2016 ◽  
Vol 43 (4) ◽  
pp. 225-234 ◽  
Author(s):  
MARISE GOUVÊA ◽  
CRISTIANE DE OLIVEIRA NOVAES ◽  
ANTONIO CARLOS IGLESIAS
Keyword(s):  
Antibiotic Prophylaxis ◽  
Prophylactic Antibiotic ◽  
University Hospital ◽  
Surgical Patients ◽  
Antibiotic Administration ◽  
Surgical Antibiotic Prophylaxis ◽  
The Right

ABSTRACT Objective : to evaluate the antibiotic prophylaxis in surgical patients at the Gaffrée e Guinle University Hospital - HUGG. Methods : we conducted a rospective study of a cohort of 256 patients undergoing elective operations between January and September 2014. We collected data on demographics, use or not of prophylactic antibiotic and the antibiotic prophylaxis following characteristics: type of antibiotic used, moment of administration and duration of postoperative use. The analyzed outcomes were "justified use or non-use of antibiotic prophylaxis", "correct antibiotic choice," "administration of the antibiotic at the right time" and "discontinuation of the antibiotic at the right time." Results : antibiotic prophylaxis was used in 91.8% of cases. The use or non-use of antibiotic prophylaxis was justified in 78.9% of patients, the choice of the administered antibiotic was considered correct in 97.9%, antibiotic administration was made at the right time in only 27.2% of patients and discontinuation of the antibiotic was performed at the correct time in 95.7% of cases. Conclusion : the surgical antibiotic prophylaxis was not fully adequately performed in the sample.

Prophylactic Antibiotic Administration in Vascular Interventional Radiology

2018 ◽  
Vol 37 (2) ◽  
pp. 77-84
Author(s):  
Melanie Camp ◽  
Jennan Phillips ◽  
Cynthia Selleck
Keyword(s):  
Interventional Radiology ◽  
Prophylactic Antibiotic ◽  
Antibiotic Administration

scholarly journals A Prospective Evaluation of Adverse Reactions to Single-Dose Intravenous Antibiotic Prophylaxis During Outpatient Hand Surgery

Hand ◽  
2018 ◽  
Vol 15 (1) ◽  
pp. 41-44 ◽  
Author(s):  
Kristin Sandrowski ◽  
David Edelman ◽  
Michael Rivlin ◽  
Christopher Jones ◽  
Mark Wang ◽  
...  
Keyword(s):  
Adverse Reaction ◽  
Single Dose ◽  
Antibiotic Prophylaxis ◽  
Upper Extremity ◽  
Adverse Reactions ◽  
Prophylactic Antibiotic ◽  
Hand Surgery ◽  
Outpatient Setting ◽  
Study Cohort ◽  
Antibiotic Administration

Background: While it is established that routine prophylactic antibiotics are not needed for all hand surgery, some cases do require it. The purpose of this study was to determine the rate of adverse reactions resulting from prophylactic antibiotic administration on patients undergoing outpatient hand and upper extremity surgical procedures. We hypothesize that the rate of complications resulting from the use of antibiotic prophylaxis is smaller than that reported in the currently referenced literature. Methods: We prospectively evaluated 570 consecutive patients undergoing outpatient upper extremity surgery. Patients were excluded if they were on antibiotics prior to surgery, were discharged on antibiotics, or if they wished to be excluded. Nineteen patients were excluded, resulting in a study cohort of 551 patients. Patients were monitored perioperatively, 2 to 3 days postoperatively, during the first postoperative visit and 1 month postoperatively for adverse reactions. The type and timing of the adverse reaction was recorded. Results: Five hundred fifty-one patients were included for evaluation and 8 patients (1.5%) developed an adverse reaction to antibiotics. Five patients (0.9%) reported a rash and 3 patients (0.5%) reported diarrhea within 3 days of surgery. There were no anaphylactic reactions or complications necessitating hospital transfer or admission in the postoperative period. Conclusion: This study represents a prospective investigation designed to determine the rate of adverse reactions to single-dose antibiotics given during outpatient hand surgery. We conclude that the use of intravenous, single-dose prophylactic antibiotic is safe in the outpatient setting for cases that require it.

Surgical shunt infection: significant reduction when using intraventricular and systemic antibiotic agents

2006 ◽  
Vol 105 (2) ◽  
pp. 242-247 ◽  
Author(s):  
Brian T. Ragel ◽  
Samuel R. Browd ◽  
Richard H. Schmidt
Keyword(s):  
Antibiotic Therapy ◽  
Prophylactic Antibiotic ◽  
Shunt Infection ◽  
Controlled Study ◽  
Csf Shunt ◽  
Antibiotic Administration ◽  
Systemic Antibiotic ◽  
Group I ◽  
Group Ii ◽  
Antibiotic Agents

Object Infection represents the most common serious complication of shunt surgery, and typically its incidence ranges between 5 and 15%, despite the use of systemic antibiotic agents. Because systemic antibiotic medications generally penetrate the cerebrospinal fluid (CSF) poorly, the authors investigated, in a controlled study, whether the addition of intraventricular antibiotic treatment decreases the incidence of perioperative infection in adult patients. Methods Data pertaining to all CSF shunt procedures conducted at the authors’ institution during an 11-year period were reviewed. Perioperative infection was defined as culture-positive CSF and the clinical presence of infection-related symptoms occurring within 90 days of surgery. All patients underwent intraoperative systemic antistaphylococcal antibiotic therapy. Before May 16, 1999, the senior author (R.H.S.) also administered 4 mg of gentamicin intraventricularly at surgery (Group I); thereafter, 10 mg of vancomycin was additionally administered (Group II). Other neurosurgeons at this institution did not use intraventricular antibiotic therapy, and their patients served as additional controls in identical time periods (Groups III and IV). A total of 802 shunt procedures were performed in 534 patients. Control infection rates were 5.4% (eight of 147) in Group I; 6.2% (nine of 145) in Group III; and 6.7% (18 of 267) in Group IV. With the combination of systemic antibiotic and intraventricular gentamicin and vancomycin (Group II), the infection rate fell significantly to 0.4% (one of 243). No complications were noted in association with intraventricular antibiotic administration. Conclusions The combination of intraventricular gentamicin and vancomycin with systemic antibiotic therapy significantly decreased the incidence of perioperative shunt infection. It is presumed that intraventricular antibiotic therapy extends prophylactic antibiotic coverage into the CSF and prevents bacterial seeding.

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