scholarly journals Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice

2020 ◽  
Vol 13 (5) ◽  
pp. dmm042424 ◽  
Author(s):  
Anna L. Gray ◽  
Leonette Annan ◽  
James R. T. Dick ◽  
Albert R. La Spada ◽  
Michael G. Hanna ◽  
...  
2019 ◽  
Vol 19 (2) ◽  
pp. 27-36 ◽  
Author(s):  
M Dopsaj ◽  
A Nenasheva ◽  
T Tretiakova ◽  
Yu Syromiatnikova ◽  
E Surina-Marysheva ◽  
...  

The Aim. The aim of this paper is to define the contractile characteristics of maximal isometric handgrip force and to establish possible differences between the students of the Universities of Chelyabinsk and Belgrade. The secondary aim is to create a practically applicable initial model in order to explore the mentioned characteristics in the future. Material and methods. For the purposes of this research, the overall sample of 225 subjects was tested. 91 subjects were from Russia and 134 were from Serbia. The results were gathered using a strain gage and a standardized isometric handgrip test protocol. The contractile properties of HG muscle force were measured in relation to three different contractile dimensions: the maximal muscle force (Fmax), the maximal explosive muscle force (RFDmax), the time need for achieving maximal (tFmax) and maximal explosive (tRFDmax) muscle force. Results. This study has shown that there are no generally statistically significant differences for all observed variables of HG contractile characteristics between tested Russian and Serbian students. Based on the results of the present study, six different models of the equation for evaluation of HG contractile characteristics of female and male students, i.e. young adults, were made. All defined models are highly statistically significant, accurate and sensitive in the prediction of the general distributive position of an individual or particular group of subjects in relation to the measured contractile characteristics. Conclusions. The obtained results can generally indicate the stability of potential to exert the given contractile characteristic in relation to the population of similar evolutionary (Slavs) at different geographical background.


Author(s):  
Stefan Marković ◽  
Milivoj Dopsaj ◽  
Vladimir Koprivica ◽  
Goran Kasum

The aim of this paper is to define the initial quantitative and qualitative multidimensional model for evaluating basic contractile characteristics of isometric muscle force in systematically trained and selected cadet judo athletes. In this research absolute values of the obtained results, and values derived by relativization of absolute values in relation to skeletal muscle mass (SMM) were considered. The basic method used in this research was laboratory testing. All data sampling was performed by the dynamometry method, using tensiometric probes. The research sample in this study consisted of 21 cadet judo athletes, of which 14 were male and 7 were female. All measurements were performed using standardized testing procedures on the following muscle groups: flexor muscles of the left (HGL) and the right hand (HGR), back (DL) and leg extensor muscles (LE) and ankle joint plantar flexor muscles (PF). Based on the obtained results, separate multidimensional mathematical models for the estimation of contractile potential and development level were defined for both basic characteristics of isometric muscle force: maximal isometric muscle force (Fmax) and maximal explosive isometric muscle force (RFDmax). A qualitative assessment of contractile potential for each of the tested muscle groups, i.e. variables, was enabled by defining standard values for 7 distinct preparedness levels for both basic isometric muscle force contractile characteristics of male and female cadet judo athletes.


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