scholarly journals Gallic Acid and Dodecyl Gallate Prevents Carbon Tetrachloride-Induced Acute and Chronic Hepatotoxicity by Enhancing Hepatic Antioxidant Status and Increasing p53 Expression

2017 ◽  
Vol 40 (4) ◽  
pp. 425-434 ◽  
Author(s):  
Marlene Raimunda Andreola Perazzoli ◽  
Camila Katerin Perondi ◽  
Cesar Milton Baratto ◽  
Evelyn Winter ◽  
Tânia Beatriz Creczynski-Pasa ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Gallic Acid ◽  
Antioxidant Status ◽  
P53 Expression ◽  
Dodecyl Gallate

Combination of donepezil and gallic acid improves antioxidant status and cholinesterases activity in aluminum chloride-induced neurotoxicity in Wistar rats

2021 ◽  
Author(s):  
Tajudeen O. Obafemi ◽  
Olutumise V. Owolabi ◽  
Benjamin O. Omiyale ◽  
Blessing A. Afolabi ◽  
Oluwafemi A. Ojo ◽  
...  
Keyword(s):  
Gallic Acid ◽  
Aluminum Chloride ◽  
Antioxidant Status ◽  
Wistar Rats

scholarly journals Effects of dietary gallic acid supplementation on performance, antioxidant status, and jejunum intestinal morphology in broiler chicks

2017 ◽  
Vol 96 (8) ◽  
pp. 2768-2775 ◽  
Author(s):  
K.G. Samuel ◽  
J. Wang ◽  
H.Y. Yue ◽  
S.G. Wu ◽  
H.J. Zhang ◽  
...  
Keyword(s):  
Gallic Acid ◽  
Antioxidant Status ◽  
Intestinal Morphology ◽  
Broiler Chicks ◽  
Acid Supplementation

Mechanism of the Protective Effects of Sumac Gall Extract and Gallic Acid on the Progression of CCl4-induced Acute Liver Injury in Rats

1998 ◽  
Vol 26 (03n04) ◽  
pp. 333-341 ◽  
Author(s):  
Shigeyuki Kanai ◽  
Hideyuki Okano
Keyword(s):  
Superoxide Dismutase ◽  
Carbon Tetrachloride ◽  
Liver Injury ◽  
Protective Effect ◽  
Gallic Acid ◽  
Cell Membranes ◽  
Acute Liver Injury ◽  
Radical Scavenging ◽  
Protective Effects ◽  
Preventive Effect

To examine the mechanism of the preventive effect of tannins on the progression of carbon tetrachloride (CCl4)-induced acute liver injury in rats, sumac gall (SG) extract and gallic acid (GA) were used as substitutes for crude tannins, because SG is a kind of Chinese traditional medicinal herb containing large amounts of various tannins, and GA is one of the major constituents of SG. The protective effect of oral (p.o.) and intraperitoneal (i.p.) administration of each substance on progression of CCl4-induced hepatitis was investigated in rats. Speculating that the superoxide dismutase (SOD)-like activities (O2 radical-scavenging activities) and/or protective effects of these substances on cell membranes might play a key role in the mechanism opposing the progression of CCl4-induced hepatitis, the O2 radical-scavenging activities in liver cells and serum in rats were monitored. Both substances significantly prevented the progression of acute liver injury with both p.o. and i.p. administration. These findings suggest that the mechanism for this prevention might be due mainly to the protective effect of these substances on cell membranes rather than O2 radical-scavenging activities.

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