Role of Pharmacy in the Promotion of Drug Safety in Pharmacotherapy

6559 Background: RADAR is the only independent academic pharmacovigilance organization funded exclusively by peer-reviewed grants. We describe the role of high quality case reports in the detection of drug safety signals. Methods: RADAR has identified 11 cancer-related adverse drug reactions (ADRs). Initial reports for small numbers of cases were obtained from our own institution, NU, (4 ADRs) or from referral centers (7 ADRs). Clinicians at these centers voluntarily provided brief case reports to RADAR, who submitted detailed case reports to the FDA/manufacturer. Clinicians were promised that patient/provider data would be kept confidential and that these data would be submitted as peer-reviewed manuscripts. Results: See Table. Conclusions: RADAR was successful at signal generation and amplification because it focused on quality, not quantity of case reports. Pharmacovigilance efforts that allow clinicians to complete brief forms, maintain confidentiality of patient and provider, and result in submission of collaborative manuscripts may improve early detection of drug safety signals initiatives in oncology. [Table: see text] No significant financial relationships to disclose.

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Drug Safety: The Role of Regulatory Authorities

Aktuelle Neurologie ◽

10.1055/s-2002-27800 ◽

2002 ◽

Vol 29 ◽

pp. 47-49

Author(s):

Hans-Joachim Meencke

Keyword(s):

Drug Safety ◽

Regulatory Authorities

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Assessing Drug Safety in Children — The Role of Real-World Data

New England Journal of Medicine ◽

10.1056/nejmp1802197 ◽

2018 ◽

Vol 378 (23) ◽

pp. 2155-2157 ◽

Cited By ~ 16

Author(s):

Ann W. McMahon ◽

Gerald Dal Pan

Keyword(s):

Drug Safety ◽

Real World ◽

Real World Data ◽

World Data

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Communication in oncology pharmacy

10.1093/med/9780198736134.003.0051 ◽

2017 ◽

Author(s):

Bethan Tranter ◽

Simon Noble

Keyword(s):

Palliative Care ◽

Treatment Adherence ◽

Drug Safety ◽

Medication Compliance ◽

Healthcare Providers ◽

Optimal Drug ◽

Treatment Medication ◽

Hospice And Palliative Care ◽

Timely Treatment

Pharmacists are considered to have a pivotal role in the provision of information in oncology, and in hospice and palliative care. Effective communication is essential for optimal drug safety, timely treatment, medication compliance, and education. The role of the pharmacist has expanded to offer enhanced pharmaceutical care, which serves to improve the communication between healthcare providers and the function of the multidisciplinary team. Furthermore, through optimal communication with patients there will be increased treatment adherence and improved overall care. This chapter focuses on the breadth of communication issues faced by pharmacists involved in cancer care through the full length of the cancer journey, be it curative or palliative.

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