Quality not quantity: Key success factors from the first decade of safety reports from the Research on Adverse Drug Events and Reports project (RADAR)

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 6559-6559
Author(s):  
C. Bennett ◽  
B. J. Edwards ◽  
C. C. Tigue ◽  
D. W. Raisch ◽  
D. M. Courtney ◽  
...  
Keyword(s):  
Drug Safety ◽  
Success Factors ◽  
Adverse Drug Events ◽  
Case Reports ◽  
Signal Generation ◽  
Drug Reactions ◽  
High Quality ◽  
Key Success Factors ◽  
Safety Signals

6559 Background: RADAR is the only independent academic pharmacovigilance organization funded exclusively by peer-reviewed grants. We describe the role of high quality case reports in the detection of drug safety signals. Methods: RADAR has identified 11 cancer-related adverse drug reactions (ADRs). Initial reports for small numbers of cases were obtained from our own institution, NU, (4 ADRs) or from referral centers (7 ADRs). Clinicians at these centers voluntarily provided brief case reports to RADAR, who submitted detailed case reports to the FDA/manufacturer. Clinicians were promised that patient/provider data would be kept confidential and that these data would be submitted as peer-reviewed manuscripts. Results: See Table. Conclusions: RADAR was successful at signal generation and amplification because it focused on quality, not quantity of case reports. Pharmacovigilance efforts that allow clinicians to complete brief forms, maintain confidentiality of patient and provider, and result in submission of collaborative manuscripts may improve early detection of drug safety signals initiatives in oncology. [Table: see text] No significant financial relationships to disclose.

Information and Communication Technology Uses in Agriculture

2012 ◽  
pp. 235-251
Author(s):  
Tizita Alemayehu Wasihun ◽  
Blessing Maumbe
Keyword(s):  
Information And Communication Technologies ◽  
Value Chain ◽  
Success Factors ◽  
Communication Technologies ◽  
Value Chains ◽  
Key Success Factors ◽  
Ict Use ◽  
Strategic Role ◽  
Information And Communication

The world has experienced an unprecedented growth in information and communication technologies (ICT) through the widespread use of personal computers, Internet, and mobile phones. The objectives of this chapter are to examine trends in ICT use in agriculture, identify key success factors for ICT utilization in agriculture, and investigate the implications of ICT-enabled value chains for the agribusiness industry. The chapter describes the strategic role of ICT in the development of both e-commerce and mobile commerce in agriculture globally. The chapter identifies the leading areas of ICT use in agriculture and agribusinesses as input procurement, production, marketing, food traceability, and financial service delivery. Producers are increasingly seeking ways to add value to their businesses by integrating ICT in the value chain. Similarly, consumers are becoming more knowledgeable about how they could use ICT to articulate their preferences. The chapter discusses key success factors for ICT applications affecting both the internal and external environment of agribusiness firms. The chapter concludes by drawing implications for ICT use in agriculture and agribusiness value chains.

scholarly journals Difficulties in Building Relationships with External Stakeholders: A Family-Firm Perspective

2018 ◽  
Vol 10 (12) ◽  
pp. 4557
Author(s):  
Joanna Sadkowska
Keyword(s):  
Project Management ◽  
Family Involvement ◽  
Success Factors ◽  
Family Firms ◽  
Management Practices ◽  
Eastern European ◽  
Building Relationships ◽  
Key Success Factors ◽  
External Stakeholders

Currently, there is a growing number of businesses which organize their operations in the form of projects. One of the key success factors in the area of project management is building successful relationships with project stakeholders. Using stakeholder theory perspective and looking through the lens of family involvement, the study addresses two research questions: 1. how do family firms perceive the difficulty in building relationships with external stakeholders compared to other project management difficulties; 2. does organizing work in the form of projects redefine the significance of family involvement in the difficulties of building relationships with external stakeholders. To answer these questions, 154 Polish family-owned enterprises, considered as representatives of Eastern European emerging economies, were surveyed. The results indicate that family involvement strongly influences the difficulties in building relationships with external stakeholders, but only in those companies which at the time of the survey were not managing projects. In the firms employing project management practices, only the factor related to increasing the number of employees had a facilitating effect on the studied phenomenon. On the contrary, in the case of family firms not managing projects, the growth in the number of employees increased the difficulty in building relationships with external stakeholders. The findings add to the research on the role of family involvement in building relationships with a firm’s external stakeholders.

scholarly journals PROGRAM INDONESIA SEHAT BERBASIS KELUARGA: KONTRIBUSI MODAL SOSIAL KEAGAMAAN DI MASYARAKAT

Kodifikasia ◽  
2019 ◽  
Vol 13 (2) ◽  
pp. 233
Author(s):  
Rohmah Maulidia ◽  
Kurnia Hidayati
Keyword(s):  
Social Capital ◽  
Success Factors ◽  
Health Workers ◽  
Health Problems ◽  
Religious Leaders ◽  
Key Success Factors ◽  
Health Institutions ◽  
Village Communities ◽  
The Village

Tulisan ini mendiskusikan peran dan partisipasi masyarakat dalam pembangunan berkelanjutan (SDGS), khususnya pembangunan kesehatan dengan memanfaatkan sumber daya manusia dan modal sosial yang dimiliki. Tokoh agama, tokoh masyarakat, masyarakat desa dan petugas kesehatan saling mempertahankan kerjasama dalam bentuk kegiatan program rutin dan pendirian lembaga kesehatan desa. Kemampuan dan nilai-nilai yang dimiliki masyarakat dan peran perangkat desa dapat menjadi faktor kunci keberhasilan. Adanya tolong menolong, rasa saling percaya (trust), dan norma yang ditaati merupakan merupakan modal dalam mengatasi persoalan kesehatan. Meski mampu mengatasi persoalan kesehatan, namun faktanya masih menyisakan persoalan. [This paper discusses the role and community participation in sustainable development (SDGS), especially health development by utilizing human resources and social capital owned. Religious leaders, community leaders, village communities and health workers maintain mutual bonding in the form of routine program activities and the establishment of village health institutions. The abilities and values of the community and the role of the village apparatus can be the key success factors. The existence of help, mutual trust, and adhered norms are social capital in overcoming health problems. Although able to overcome health problems, the fact the problem still remains] 

scholarly journals Public engagement and the role of the media in post-marketing drug safety: the case of Eltroxin® (levothyroxine) in New Zealand

2020 ◽  
Author(s):  
Kevin Dew ◽  
J Gardner ◽  
EH Morrato ◽  
P Norris ◽  
K Chamberlain ◽  
...  
Keyword(s):  
New Zealand ◽  
Adverse Drug Reactions ◽  
Drug Safety ◽  
Public Engagement ◽  
Sharp Increase ◽  
Drug Reactions ◽  
Media Attention ◽  
Adr Reporting ◽  
The Media

© 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group. The potential for harms from adverse drug reactions (ADR) constitutes a critical patient safety and public health challenge, especially with increased medication usage as populations age. The research reported here explores explanations for a sudden increase in ADR reporting in New Zealand after a new formulation of a medication to treat hypothyroidism, Eltroxin® (levothyroxine), was phased in. The formulation was adjudged to be bioequivalent to the old formulation, yet following its introduction, a sharp increase in the reporting of adverse reactions to this drug occurred. The paper analyses public engagement and the role of print media coverage, press releases and minutes of meetings of relevant agencies in order to describe the unfolding of this health controversy. Early interpretations of the sharp increase in reporting of reactions explained it as an outcome of a combination of factors, including a mistrust of state drug subsidising agencies and media attention that provoked anxiety in this vulnerable population. This paper offers an alternative explanation arguing that, as adverse drug reactions are known to be significantly underreported, the Eltroxin® ‘health scare’ illustrates enhanced pharmacovigilance triggered by the interaction between patients and the media. The Eltroxin® controversy is an illustrative case example of the amplification of ADR reporting by patients following increased media attention in the context of a low consumer reporting environment. The case of Eltroxin® indicates that drug safety can be enhanced by actively using media sources and by encouraging patient engagement and reporting of ADRs.

scholarly journals Public engagement and the role of the media in post-marketing drug safety: the case of Eltroxin® (levothyroxine) in New Zealand

2020 ◽  
Author(s):  
Kevin Dew ◽  
J Gardner ◽  
EH Morrato ◽  
P Norris ◽  
K Chamberlain ◽  
...  
Keyword(s):  
New Zealand ◽  
Adverse Drug Reactions ◽  
Drug Safety ◽  
Public Engagement ◽  
Sharp Increase ◽  
Drug Reactions ◽  
Media Attention ◽  
Adr Reporting ◽  
The Media

© 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group. The potential for harms from adverse drug reactions (ADR) constitutes a critical patient safety and public health challenge, especially with increased medication usage as populations age. The research reported here explores explanations for a sudden increase in ADR reporting in New Zealand after a new formulation of a medication to treat hypothyroidism, Eltroxin® (levothyroxine), was phased in. The formulation was adjudged to be bioequivalent to the old formulation, yet following its introduction, a sharp increase in the reporting of adverse reactions to this drug occurred. The paper analyses public engagement and the role of print media coverage, press releases and minutes of meetings of relevant agencies in order to describe the unfolding of this health controversy. Early interpretations of the sharp increase in reporting of reactions explained it as an outcome of a combination of factors, including a mistrust of state drug subsidising agencies and media attention that provoked anxiety in this vulnerable population. This paper offers an alternative explanation arguing that, as adverse drug reactions are known to be significantly underreported, the Eltroxin® ‘health scare’ illustrates enhanced pharmacovigilance triggered by the interaction between patients and the media. The Eltroxin® controversy is an illustrative case example of the amplification of ADR reporting by patients following increased media attention in the context of a low consumer reporting environment. The case of Eltroxin® indicates that drug safety can be enhanced by actively using media sources and by encouraging patient engagement and reporting of ADRs.

scholarly journals Key Success Factors to Increase Value Proposition in the Hospitality Industry

2019 ◽  
Vol 2 (1) ◽  
pp. 34
Author(s):  
Daniel Marco - Stefan Kleber ◽  
Tatjana Volkova
Keyword(s):  
Hospitality Industry ◽  
Success Factors ◽  
Design Thinking ◽  
Value Proposition ◽  
Customer Needs ◽  
Key Success Factors ◽  
Dynamic Markets ◽  
Research Article ◽  
Conceptual Study

Purpose of this conceptual study is the identification and analysis of key success factors to increase value proposition based on design thinking of hotel executives and value co-creation with customers in the hospitality industry. Globalized dynamic markets and ever-changing customer needs and demands require ongoing experimentation and communication to steadily identify customer needs and wants in order to adjust products and services to ensure an increase of value proposition. In this research article, the two-fold role of customers and hotel executives in value co-creation processes leading to an identification of key success factors of value proposition increase is analyzed. The article emphasizes the essential role of customers as contributors to value co-creation processes and hotel executives as contributors to the creation and delivery of value proposition. Superior value proposition can be achieved by understanding actual needs and demands of customers based on design thinking and comparing them to value proposition elements that are perceived as being important by customers. Following this approach, key success factors for enhancing value proposition are analyzed.

Managing reversed (global) outsourcing – the role of knowledge, technology and time

2018 ◽  
Vol 29 (4) ◽  
pp. 676-698 ◽  
Author(s):  
Bella Belerivana Nujen ◽  
Lise Lillebrygfjeld Halse ◽  
Rickard Damm ◽  
Hallgeir Gammelsæter
Keyword(s):  
Success Factors ◽  
Advanced Manufacturing ◽  
Structured Interviews ◽  
Content Type ◽  
Global Outsourcing ◽  
Key Success Factors ◽  
Sourcing Strategies ◽  
Emergent Literature ◽  
Industry Sectors

Purpose Against the recent trend toward reversed global outsourcing, the purpose of this paper is to provide insights on how the internal process can be handled once the decision on reverse outsourcing has been made. The authors focus in particular on in-house knowledge and technology requirements. Design/methodology/approach To explore the topic at hand, the researchers conducted in-depth semi-structured interviews with five companies operating in two different industry sectors. Findings Reversed outsourcing accentuates challenges relating to retained knowledge. When embarking on reversed outsourcing, companies need to acknowledge the effort to revive and renew capabilities in order to perform technical operations and advanced manufacturing production. Research limitations/implications The research is based on case studies in a Scandinavian context. Further empirical research from other high-cost locations is needed to validate the findings. Originality/value Explorative qualitative research is scarce in the emergent literature on reversed outsourcing. The paper provides practical and theoretical insights into how to handle diminishing knowledge in companies that are re-evaluating their sourcing strategies. It adds a knowledge dimension within the emergent literature. A framework for key success factors and propositions is also provided.

Clinical trials, case reports, and observational databases as sources of information on serious cancer-related adverse drug reactions (sADRs): Lessons learned from the Research on Adverse Drug Events and Reports (RADAR) project

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 19591-19591
Author(s):  
C. Bennett ◽  
K. Gleason ◽  
B. Djulbegovic ◽  
D. Raisch
Keyword(s):  
Organ Failure ◽  
Adverse Drug Reactions ◽  
Adverse Drug Events ◽  
Case Reports ◽  
Clinical Information ◽  
Lessons Learned ◽  
Sources Of Information ◽  
Drug Reactions ◽  
Fda Approval ◽  
Black Box Warnings

19591 Background: Serious adverse drug reactions (sADRs) such as venous thromboembolism resulting from cancer pharmaceutical use are underappreciated and often misattributed to the cancer diagnosis, rather than the therapy. The Research on Adverse Drug events And Reports (RADAR) group evaluated factors associated with identification of serious cancer-related sADRs (i.e. an adverse drug reaction that results in death or severe organ failure). Methods: Information on sources of clinical information, incidence, setting, and time from FDA approval to initial identification was obtained for sADRs that resulted in death or severe organ failure. Most of the ADRs are described as Black Box warnings or in “Dear Doctor” letters. Results: Summarized in table . Conclusion: Clinical trial safety reports from off-label settings facilitate identification of common (>3% rate) cancer associated sADRs. Case reports and observational databases from on-label settings facilitate detection of rare cancer-associated sADRs (<1%) often at lengthy time intervals from initial FDA approval. No significant financial relationships to disclose. [Table: see text]

Perceived Causes of Success in Small Business

1986 ◽  
Vol 11 (2) ◽  
pp. 41-50 ◽  
Author(s):  
A. B. Ibrahim ◽  
J. R. Goodwin
Keyword(s):  
New York ◽  
Small Business ◽  
Small Businesses ◽  
Small Firms ◽  
Success Factors ◽  
Geographical Location ◽  
Managerial Skills ◽  
Key Success Factors ◽  
Small Business Management

This empirical research is a pilot study which endeavours to identify a set of variables associated with successful small businesses. Seventy-four (74) small firms operating in Montreal responded to a lengthy questionnaire and an intensive interview. From this data three variables were initially identified. A replication study of seventy small firms located in Burlington, Vermont and Plattsburgh, New York, was carried out in order to observe whether the identified variables were duplicated beyond a certain geographical location. Using factor analysis on the data, the authors were able to delineate entrepreneurial behavior and managerial skills as key success factors in small business management. This finding underscores the role of entrepreneurship education in developing both the behavioral and the managerial skills in the owner/manager.

Sign in / Sign up

Export Citation Format

Share Document