scholarly journals Can Financial Engineering Cure Cancer?

2013 ◽  
Vol 103 (3) ◽  
pp. 406-411 ◽  
Author(s):  
David E Fagnan ◽  
Jose Maria Fernandez ◽  
Andrew W Lo ◽  
Roger M Stein

Traditional financing sources such as private and public equity may not be ideal for investment projects with low probabilities of success, long time horizons, and large capital requirements. Nevertheless, such projects, if not too highly correlated, may yield attractive risk-adjusted returns when combined into a single portfolio. Such “megafund” portfolios may be too large to finance through private or public equity alone. But with sufficient diversification and risk analytics, debt financing via securitization may be feasible. Credit enhancements (i.e., derivatives and government guarantees) can also improve megafund economics. We present an analytical framework and illustrative empirical examples involving cancer research.

2021 ◽  
Vol 183 ◽  
pp. 158-174
Author(s):  
Patrick Lloyd-Smith ◽  
Wiktor Adamowicz ◽  
Alicia Entem ◽  
Eli P. Fenichel ◽  
Mani Rouhi Rad

Author(s):  
S.V. x S.V. Radygina

The article discloses the essence of the public-private partnership mechanism, various approaches to its definition, both at the level of legislative acts of the Russian Federation and international organizations (UN). Different forms of PPP projects, their peculiarities and distinctive features are described in accordance with federal laws on public-private partnership and concession agreements. Instruments are being considered to support investors implementing investment projects of social infrastructure on the basis of PPPs, from federal and regional development institutions, as well as state authorities. An analysis of the level of PPP development in the Udmurt Republic is carried out, concrete examples of successful cooperation between private and public parties on the organization of financing and implementation of the project on the basis of public-private or municipal-private partnership are given. The use of this mechanism allows to obtain a significant economic effect due to the fact that there is a personal interest of a private person in obtaining income from a built or modernized facility. In addition, the social component plays an important role, PPP allows you to direct funds to those industries that are initially considered not promising enough to conduct business, but are often of key importance for the development of the region and ensuring a comfortable urban environment for the population.


2009 ◽  
Vol 75 (3) ◽  
pp. 419-435 ◽  
Author(s):  
Pan Suk Kim

Quality management generally implies all the activities that are intended to bring about the desired level of quality. In order to improve the quality of a product or service in both private and public sectors, quality management has been exercised for a long time and broadly applied in various organizations. As many new buzz words emerge in both business and public management, however, it seems that its popularity has declined. Is quality management dead? Not really. Quality is a fundamental ingredient in innovation so it must not be disregarded, although there might be fluctuations in its popularity. This study reviews the developmental status of quality management in South Korea by looking at its status and conceptual changes from historical and comparative perspectives. Historically, quality management in modern Korea was influenced by Japanese and American practices. In a comparative perspective, however, European influence on quality management was not salient in Korea. Points for practitioners More buzz words or fads will be generated by issue entrepreneurs and business consultants. However, quality management will not fade away. Continuous improvement is an endless open-ended journey, as is quality management. It is fair to say that the need for government reform and innovation will never be exhausted. Therefore, the importance of quality management will be a continuing reality in the future, perhaps with some adjustment of its rhetoric or riding on an irresistible wave of reform for adaptation. Quality has been reflected through innovation, and vice versa.


2018 ◽  
Vol 14 (4) ◽  
pp. 465-487 ◽  
Author(s):  
Kim P. Huynh ◽  
Teodora Paligorova ◽  
Robert Petrunia

Author(s):  
OJS Admin

A number of teachers are teaching all over Pakistan among private and public institutes. Voice problem is specified to be one of the major occupational risks of teachers actually the teachers frequently use theirvoice with high-intensity in noisy environment for a long time and without voice rest.


Author(s):  
Lucia Quaglia

This chapter begins by reviewing several bodies of scholarly works that are relevant to this research, notably, the international relations literature on regime complexity and the international political economy literature on financial regulation. It then discusses three mainstream theoretically informed explanations—a state-centric, a transgovernmental, and a business-led accounts—which can be useful to explain how regime complexity in derivatives was dealt with. Finally, it outlines the research design, the analytical framework, the methodology, the sources, the timeframe, and the empirical coverage. Empirically, this book examines all the main aspects concerning the regulation of derivatives markets, namely: trading, clearing and reporting derivatives; resilience, recovery and resolution of central counterparties; capital requirements for bank exposures to central counterparties and derivatives; margins for derivatives non-centrally cleared via central counterparties.


2010 ◽  
Vol 13 (3) ◽  
pp. 329-344 ◽  
Author(s):  
Derek Schraader ◽  
Louise Whittaker ◽  
Ian McKay

This paper describes a case study undertaken to determine whether formal sector personal debt financing might contribute to the funding of South African informal market traders. The case study was conducted at the Natalspruit informal market in Ekhuruleni, Gauteng1.  Quantitative questionnaire surveys and a financial diaries project established that market traders in the Natalspruit informal market: have capital requirements large enough to justify the use of formal sector debt financing, can generate sufficient operating profits to pay for formal sector debt financing, and would be willing to utilise formal sector debt financing if given the opportunity. However, formal sector debt financing is most relevant to those informal market traders with the skills and motivation to utilize financing provided effectively and who are willing to inject more formality into their business.


2009 ◽  
Vol 2009 (122) ◽  
pp. 19-29 ◽  
Author(s):  
Raymond Gullison ◽  
Jared Hardner

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