Pharmacotherapy of female urinary incontinence

2005 ◽  
Vol 11 (4) ◽  
pp. 160-165 ◽  
Author(s):  
Gert Naumann ◽  
Heinz Koelbl

Urinary incontinence is a major clinical problem and a significant cause of disability and dependency in older adults. Overall, the prevalence of urinary incontinence approaches 55% among women aged over 55 years. The past few years have seen significant advances in the pharmacotherapy of overactive bladder and stress incontinence. The review examines the evidence regarding their benefits and side-effects.

2018 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.


2010 ◽  
Vol 16 (1) ◽  
pp. 17
Author(s):  
F. Magatti ◽  
P.L. Sirtori ◽  
C. Rumi ◽  
C. Belloni

In this study we determined the efficacy of TVT for the treatment of female urinary incontinence in a first group of patients (69) of our urogynaecology service from April 1998 to December 2000. The TVT procedure is a minimally invasive technique, using local or spinal anaesthesia, which consists in the implantation of a Prolene tape around the mid-urethra. On the basis of our results (92.3 % success rate) we consider the TVT procedure to be a safe and effective surgical procedure for the treatment of female urinary stress incontinence.


2010 ◽  
Vol 14 (2) ◽  
pp. 51
Author(s):  
A. BERNABEI ◽  
Va. TROTTA ◽  
Vi. TROTTA

A retrospective study of patients of the Urogynaecological Unit in Siena is reported. Out of 228 women examined, 141 had urinary incontinence (stress incontinence 110, urge incontinence 18, mixed 13). Predisposing factors and risk factors were investigated. A parallel study in a non-selected population of women was performed by means of a questionnaire of self-evaluation for urinary incontinence. About 20% of this population had urinary incontinence to some degree, but only a small percentage of these women had already sought medical advice.


2017 ◽  
Vol 30 (1) ◽  
Author(s):  
Mário Maciel De Lima Junior ◽  
Elizângela Castelo Branco

Urinary incontinence (UI) is a significant health problem leading to physical, psychological and social discomfort, especially in elderly women. A study of prevalence and classification of UI in the Roraima state was taken up to aid in formulation of healthcare policy and improvement of patient referral facilities. A retrospective study of 765 female patients who have undergone urodynamic examination between November 2013 and December 2014 has been conducted. Subjects were classified in to diagnostic classes: normal, stress incontinence, mixed incontinence, sensitive emergency, overactive bladder, and others. The overall prevalence of UI was 58.4%. The highest prevalence was observed in the menopausal age group (45- 49 years). Among the etiologies of UI, stress incontinence ranked highest at 30.9%, followed by overactive bladder at 6.9%. In the 25-55 years age group, stress incontinence was predominant (50-63%), while overactive bladder became significant (14-44%) in later years. The prevalence of UI in women in the state of Roraima, was high, in line with its prevalence in Brazil, as well as other western countries.


2017 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.


2011 ◽  
Vol 25 (1) ◽  
pp. 18
Author(s):  
Dorota Borawski ◽  
Martin H. Bluth ◽  
Wellman W. Cheung

To study the prevalence and risk factors of the overactive bladder, urinary incontinence and other lower tract urinary symptoms in patients with uterine myomas, female patients with established diagnosis of the uterine myomas presenting to gynecology clinic were invited to answer a self-administered questionnaire, which included questions on evidence of lower urinary tract symptoms [modified Overactive Bladder-Validated 8-question Screener (OAB-V8)]. Demographic data, relevant medical and surgical history, and pelvic ultrasound findings were reviewed from the patients charts. Statistical significance of relationship between OAB, stress incontinence and urge incontinence in relation to body mass index (BMI), uterine volume and size of dominant myoma were analyzed using 2-taild exact Fisher test and Wilcoxon test. Ninty-eight patients (28 to 81 years) completed the questionnaire over a period of 3 months. The majority were premenopausal and had detectable myomas on ultrasound. OAB was present in 47.9% women. No significant statistical relation between size and volume of the uterus and overactive bladder, urge incontinence, stress incontinence and mixed incontinence was noted. Observation of OAB subtypes with urge and stress incontinence in premenopausal patients with uterine myomas was statistically significant in comparison with premenopausal women studied (60.8% <em>vs</em> 15.3 and 63% <em>vs</em> 6.8, respectively; P&lt;0.001). Overall prevalence of OAB was similar in both groups. Our study showed the higher prevalence of overactive bladder than in the general population, however overall OAB prevalence related to fibroids did not show statistical significance. OAB-stress incontinence and OABurge incontinence subtypes were associated with uterine myomas.


2019 ◽  
Vol 65 (4) ◽  
Author(s):  
Agnieszka Licow ◽  
Sylwester Ciećwież ◽  
Magdalena Ptak ◽  
Dariusz Kotlęga ◽  
Andrzej Starczewski ◽  
...  

Overactive bladder affects 12–17% of the population, and mainly women, and its incidence increases with age. Diagnosis of this condition is based mainly on the patients’ complaints. These symptoms significantly affect the quality of life of millions of patients, involving considerable social, psychological, professional, physical and sexual problems. The wide incidence of this condition makes it necessary to find new medical substances in order to effectively eliminate the symptoms. Neurotoxins are a group of medical drugs that hold great promise for the future. Botulinum toxin is currently being used to treat  symptoms related to overactive bladder. It can constitute an appropriate therapeutic option, in  particular with regard to patients for whom the use of standard anti-cholinergic drugs is unsatisfactory or leads to severe side effects. Numerous research studies confirm that botulinum toxin can be  efficiently used in the treatment of overactive bladder. The properties of this neurotoxin allow selective  deactivation of overactive muscles. The use of botulinum toxin can be a method of treatment that significantly improves patient quality of life.Keywords: botulinum toxin; overactive bladder; urinary incontinence; quality of life.


2018 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.


Sign in / Sign up

Export Citation Format

Share Document