Genome-Wide Analysis of the Effects of Location and Number of Stress Response Elements on Gene Expression in Saccharomyces cerevisiae

2008 ◽  
Vol 106 (5) ◽  
pp. 507-510 ◽  
Author(s):  
Katsunori Yoshikawa ◽  
Chikara Furusawa ◽  
Takashi Hirasawa ◽  
Hiroshi Shimizu
2010 ◽  
Vol 77 (3) ◽  
pp. 934-941 ◽  
Author(s):  
Daisuke Watanabe ◽  
Hong Wu ◽  
Chiemi Noguchi ◽  
Yan Zhou ◽  
Takeshi Akao ◽  
...  

ABSTRACTSake yeasts (strains ofSaccharomyces cerevisiae) produce high concentrations of ethanol in sake fermentation. To investigate the molecular mechanisms underlying this brewing property, we compared gene expression of sake and laboratory yeasts in sake mash. DNA microarray and reporter gene analyses revealed defects of sake yeasts in environmental stress responses mediated by transcription factors Msn2p and/or Msn4p (Msn2/4p) and stress response elements (STRE). Furthermore, we found that dysfunction ofMSN2and/orMSN4contributes to the higher initial rate of ethanol fermentation in both sake and laboratory yeasts. These results provide novel insights into yeast stress responses as major impediments of effective ethanol fermentation.


2010 ◽  
Vol 285 (2) ◽  
pp. 125-149 ◽  
Author(s):  
Manuel J. Villa-García ◽  
Myung Sun Choi ◽  
Flora I. Hinz ◽  
María L. Gaspar ◽  
Stephen A. Jesch ◽  
...  

Gene ◽  
2014 ◽  
Vol 533 (2) ◽  
pp. 500-507 ◽  
Author(s):  
Kusum Mehla ◽  
Ankit Magotra ◽  
Jyoti Choudhary ◽  
A.K. Singh ◽  
A.K. Mohanty ◽  
...  

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