Comparing the Curative Efficacy of Different Skin Grafting Methods for Third-Degree Burn Wounds

Abstract Introduction Burn is one of the most severe traumas that causes coagulative destruction of the skin. The use of various products that accelerate wound healing in patients with burn may affect the patient’s survival and reduce the complications that may be seen. In the present study we aimed effects of subcutaneous ozone injection on second degree burn wound. Methods A total of 72 Sprague-Dawley male rats included in the study were divided randomly into three groups (control group (CG), silver sulfadiazine group (SG), ozone group (OG)) and each group was divided randomly two subgroups (as sacrificed on d7 and on d14).A deep second degree scald burns were created on the lower back. In CG subcutaneous 0.9% serum saline was injected daily into the burn area. In SG, burns were dressed with silver sulfadiazine daily and in OG subcutaneous ozone was injected daily into the burn area. Tissue hydroxyproline level measurement and histopathological evaluation were done. Results When the groups were compared in terms of weight change, no significant difference was found on the 7th and 14th days. In the evaluation made in terms of tissue hydroxyproline, tissue hydroxyproline level in OG was found to be significantly higher on both the 7th and 14th days (p < 0.001). In histopathological evaluations, it was determined that wound healing in OG was significantly higher than in the other groups. Conclusions According to the results, subcutaneous ozone therapy is more effective than silver sulphadiazine in the healing process of second-degree burn wounds and it can be safely used in the treatment of burn wounds.

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Comparative study of skin grafting with and without surgical removal of granulation tissue in chronic burn wounds

Burns ◽

10.1016/j.burns.2006.11.012 ◽

2007 ◽

Vol 33 (7) ◽

pp. 872-878 ◽

Cited By ~ 7

Author(s):

Sanjay Dhar ◽

Rakesh Saraf ◽

Anand K. Gupta ◽

Bhavani Raina

Keyword(s):

Comparative Study ◽

Granulation Tissue ◽

Skin Grafting ◽

Surgical Removal ◽

Burn Wounds

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Effect of green tea on the second degree burn wounds in rats

Indian Journal of Plastic Surgery ◽

10.4103/0970-0358.146593 ◽

2014 ◽

Vol 47 (03) ◽

pp. 370-374 ◽

Cited By ~ 8

Author(s):

Mohammad Javad Fatemi ◽

Babak Nikoomaram ◽

Amir Asadollah Khajeh Rahimi ◽

Donya Talayi ◽

Shahrzad Taghavi ◽

...

Keyword(s):

Green Tea ◽

Healing Process ◽

Digital Camera ◽

First Aid ◽

Control Group ◽

Burn Wounds ◽

Beneficial Effects ◽

Pathologic Evaluation ◽

Degree Burn ◽

Second Degree

ABSTRACT Background: Various studies indicate that the green tea has anti-inflammatory and anti-oxidative properties. Moreover, a few studies have been carried out that demonstrate beneficial effects of green tea on burned patients. Materials and Methods: In this study, green tea, Vaseline, and silver sulfadiazine dressings were used as first-aid treatment to deep dermal contact burns in rats, compared with a control of nothing. After creating second-degree burn on the dorsum of rats, the treatments were applied for 15 min in four groups. Wound dressing changes were daily. Macroscopic study was performed on days 1, 3, 7, and 14 by using a digital camera and software processing of photos. Microscopic examination was done by pathologic evaluation of skin specimens on day 14. Results: We observed that green tea usage significantly decreased burn size in comparison to the control group (P = 0.004). Conclusion: Green tea is effective on healing process of second degree burn wounds.

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347 Clinical Observation on the Application of Ultra-thin Eschar Shaving in the Treatment of Deep Second Degree Burn Wounds

Journal of Burn Care & Research ◽

10.1093/jbcr/iry006.269 ◽

2018 ◽

Vol 39 (suppl_1) ◽

pp. S144-S144

Author(s):

Y Chi ◽

F Li ◽

Q Hu ◽

H Yin ◽

J Chai

Keyword(s):

Clinical Observation ◽

Burn Wounds ◽

Degree Burn ◽

Second Degree

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ALOE VERA VS. SILVER SULFADIAZINE FOR TREATING SECOND-DEGREE BURN WOUNDS: EVIDENCE-BASED CASE REPORT

International Journal of Applied Pharmaceutics ◽

10.22159/ijap.2019.v11s6.33580 ◽

2019 ◽

pp. 146-148

Author(s):

CLARA MENNA ◽

NABILLA CALISTA ◽

LEORCA AURINO ◽

ADISTI DWIJAYANTI

Keyword(s):

Clinical Trials ◽

Risk Reduction ◽

Randomized Clinical Trials ◽

Aloe Vera ◽

Silver Sulfadiazine ◽

Number Needed To Treat ◽

Burn Wounds ◽

The Third ◽

Degree Burn ◽

Second Degree

Objective: Current treatment for second-degree burn wounds, including silver sulfadiazine (SSD) application, may cause side effects such as delayed and incomplete wound healing, leaving a scar. Traditional plants empirically used for burn wounds, such as Aloe vera, seem to be a promising option with good safety profiles. Methods: We therefore compared Aloe vera to SSD for second-degree burn wounds based on a review of clinical trials obtained by an organized search through the Cochrane, PubMed, and DynaMed databases. Three randomized clinical trials studies were selected, two of which were critically appraised. The third study, with a different outcome assessment, was analyzed separately. Results: Two studies showed that Aloe vera was more effective in treating second-degree burn wounds than SSD 1% with an absolute risk reduction of 0.2, relative risk reduction of 0.83–1.0, and number needed to treat five patients. The Aloe vera group showed faster healing, earlier epithelialization, and earlier pain alleviation. The third study combined Aloe vera with other herbs, which showed better healing ability and restored skin hydration than those with SSD. Conclusion: Each of the three articles stated that Aloe vera was more effective than SSD for treating second-degree burn wounds. Nevertheless, each of the studies lacked methodology and comprehensive data reporting.

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