Research Progress of Platelet-Rich Plasma in the Treatment of Knee Joint Diseases

2021 ◽  
Vol 11 (03) ◽  
pp. 862-865
Author(s):  
宜橙 李
1981 ◽  
Vol 10 (1) ◽  
pp. 39-43 ◽  
Author(s):  
M Nissan

The internal equilibrium of human joints has been dealt with by many investigators, either as a means for better understanding and treating joint diseases or as a basis for prosthetic design. In all cases there is less information than needed for an accurate solution, and the investigators have to use simplifying geometry and restricting assumptions. In this work a permutation method was used, which takes advantage of big computer facilities in order to reduce the number of assumptions needed. The method was used for the case of the knee joint. The results were compared to those available using a regular method, showing the permutation one to be superior.


2020 ◽  
Vol 2 (1) ◽  
pp. e1-e12
Author(s):  
Ashok Kumar ◽  
Anikait Ghosh Kadamb ◽  
Krish Ghosh Kadamb

BackgroundComparative studies of platelet-rich plasma (PRP) and hyaluronic acid show variable results. PurposeA review was conducted to understand the current role of PRP and its efficacy versus hyaluronic acid in osteoarthritis (OA) of the knee joint. MethodsOut of 170 identified studies, 14 studies involving 1575 patients with 637 males and 938 females were selected based on PRISMA flow chart guidelines and were analyzed for the study. ResultsA standard PRP regimen consisting of 2–3 intra-articular injections (IA) of 4–6 mL of leucocyte poor PRP at 1–2 weekly intervals provides a better result than HA during the first 3–6 months, and which may continue up to one year. PRP and HA may have synergistic effect; pain and swelling are the two most com-mon complications with PRP, the incidence is more with leucocyte rich PRP (LP-PRP) and intra-osseous PRP treatment.ConclusionPRP provides hope and is more effective than hyaluronic acid in pain relief and improving the quality of life in mild to moderate osteoarthritis of the knee joint. However, hype, that is effective in all, irrespective of grades of OA, mal-aligned or stiff knee, ligamentous laxity, and can avoid joint replacement is a big hindrance in establishing it as a preferred treatment in OA knee. The author follows the above-mentioned PRP regimen; and recommends to combine leucocyte poor PRP with HA for IA injections & with LP-PRP injections along with the two most common painful points (medial collateral ligament, pesanisernius) in a highly painful OA knee. PRP may not address extra-articular causes of knee pain (mal-alignment, muscle wasting, tendinosis), should be corrected for optimum outcome. Contact sports, running, exercises putting pressure on knee and NSAID should be avoided during PRP treatment. Also, more randomized controlled trials are required to further standardize the PRP preparation, administration, injection interval & proper documentation of efficacy and complications in the regenerative registry.


2021 ◽  
Vol 9 (4) ◽  
pp. 106-110
Author(s):  
Zhang Yueyu ◽  
Song Aiqun ◽  
Peng Ying

Osteoarthritis of the knee is a common clinical degenerative disease, which occurs in middle-aged and elderly people. Acupuncture therapy has a significant effect in the treatment of knee osteoarthritis, and is gradually accepted by more and more patients. Observing the treatment of knee osteoarthritis by different acupuncture and moxibustion therapies, we can find that acupuncture treatment of knee osteoarthritis has the advantages of relieving knee joint pain, improving knee joint function, absorbing knee joint inflammation, and promoting the recovery of damaged soft tissue. The treatment of osteoarthritis provides a more effective treatment plan.


2014 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
ElgeiliAdam Yousif ◽  
AlsafiAhmed Abdella ◽  
BushraHussien Ahmed ◽  
QurashiMohammed Ali

2012 ◽  
Vol 24 (2) ◽  
pp. 70-78 ◽  
Author(s):  
Yong-Geun Park ◽  
Seung Beom Han ◽  
Sang Jun Song ◽  
Tae Jin Kim ◽  
Chul-Won Ha

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Ning Zhang ◽  
Yong-Ping Wu ◽  
Sheng-Jun Qian ◽  
Chong Teng ◽  
Shuai Chen ◽  
...  

Platelet-rich plasma (PRP) therapy is a recently developed technique that uses a concentrated portion of autologous blood to try to improve and accelerate the healing of various tissues. There is a considerable interest in using these PRP products for the treatment used in bone deficiency healing. Because PRP products are safe and easy to prepare and administer, there has been increased attention toward using PRP in numerous clinical settings. The benefits of PRP therapy appear to be promising, and many investigators are exploring the ways in which this therapy can be used in the clinical setting. At present, the molecular mechanisms of bone defect repair studies have focused on three aspects of the inflammatory cytokines, growth factors and angiogenic factors. The role of PRP works mainly through these three aspects of bone repair. The purpose of this paper is to review the current evidence on the mechanism of the effect of PRP in bone deficiency healing.


2020 ◽  
Vol 6 (3) ◽  
pp. 720-723
Author(s):  
Dr. Atul Rai Sharma ◽  
Harkirat Thind ◽  
Ravish Grag ◽  
Gurmeen Garg

2021 ◽  
Vol 10 (3) ◽  
pp. 29-29
Author(s):  
Yiqiu Cao ◽  
Xiaoxuan Zhu ◽  
Ruixin Zhou ◽  
Yayi He ◽  
Zhourui Wu ◽  
...  

Author(s):  
V. I. Tatarenkov ◽  
S. M. Maksimov ◽  
V. G. Bulgakov ◽  
N. S. Gavryushenko ◽  
D. V. Martynov ◽  
...  

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