scholarly journals Case report: Heterotopic intrarenally located adrenocortical oncocytoma

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 73 ◽  
Author(s):  
Konstantin Godin ◽  
Nicole Bang ◽  
Yuri Tolkach
Keyword(s):  
Preoperative Diagnosis ◽  
Adrenal Tumor ◽  
Histopathological Examination ◽  
Perioperative Period ◽  
Diagnostic Features ◽  
Oncocytic Variant ◽  
Adrenal Masses ◽  
Adrenal Rest ◽  
Oncocytic Adenoma ◽  
Oncocytic Neoplasm

The clinical case of a 65-year-old woman with an incidentally detected left-sided mass in the upper renal pole is presented. A functional adrenal tumor was excluded. The mass was removed retroperitoneoscopically. The perioperative period was uneventful. The histopathological examination revealed a heterotopic intrarenal adrenocortical oncocytoma.Adrenal oncocytic neoplasms are very rare, with, to the authors’ knowledge, only 159 described cases so far. Most cases are non-functioning adenomas that can reach a considerable size. Only 10 heterotopic adrenal oncocytomas have been described (three retroperitoneal and seven intraspinal cases). Although the intrarenal adrenal rest is the most frequently appearing variant of adrenal heterotopia, to the best of our knowledge, this report is the first description of an intrarenally growing adrenocortical oncocytic adenoma.In addition to retroperitoneally located oncocytomas, this case could be interesting for urological practice because there are no diagnostic features which could provide a secure preoperative diagnosis of an adrenal oncocytic neoplasm and its malignant variant. Generally accepted indications for surgery of adrenal masses have to be respected. The definitive pathologic diagnosis is in most cases surprising because of its rarity. Benign adrenal oncocytic neoplasms do not require any adjuvant treatment. The oncocytic variant of adrenocortical carcinoma generally has a poor prognosis.

scholarly journals Oncocytic Variant of Adrenocortical Carcinoma: Case Report of a Rare Malignancy

2020 ◽  
pp. 1-4
Author(s):  
Sarath Sistla ◽  
Balamourougan Krishnaraj ◽  
Gomathi Shankar ◽  
Jigish Ruparelia ◽  
Prakriti Giri ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Surgical Resection ◽  
Adrenocortical Carcinoma ◽  
Histopathological Examination ◽  
Large Mass ◽  
Disease Stage ◽  
Surgical Specimen ◽  
Oncocytic Variant ◽  
Rare Malignancy ◽  
Oncocytic Neoplasm

Adrenocortical carcinoma is a rare cancer. Oncocytic tumors of the adrenal gland are rarer. Most Oncocytic Adrenal Neoplasms are benign and carry favourable prognosis. They are classified as oncocytoma, oncocytic neoplasm of uncertain malignant potential and oncocytic adrenal carcinoma. The malignant nature of oncocytic neoplasm of adrenal gland can only be confirmed on histopathology. We report a case of a 55-year-old male with newly diagnosed hypertension being evaluated for left adrenal mass concerning for adrenocortical carcinoma. Open radical left adrenalectomy and nephrectomy was done and histopathology confirmed oncocytic variant of adrenocortical carcinoma based on Lin-Weiss-Bisceglia scoring system which has been developed particularly for oncocytic type of tumor. Though rare, oncocytic neoplasm has to be considered as one of the differential diagnoses of adrenocortical mass, especially those presenting as a large mass because malignant oncocytic neoplasm of adrenal gland as large as 23cm have been reported. Imaging modalities like ultrasonography, computed tomography or magnetic resonance imaging, though useful in evaluating an adrenocortical mass, cannot predict malignant nature of an oncocytic neoplasm. Diagnosis of adrenocortical carcinoma is therefore reliably made only after histopathological examination of the surgical specimen. Surgical resection in those presenting with nonmetastatic resectable disease remains the mainstay of ACC treatment. Oncocytic ACC compared with conventional ACCs matched for age, gender, disease stage and status of surgical resection, shows significant better overall survival thus representing more indolent variant of an aggressive and often fatal disease.

scholarly journals Case Report: Challenges on diagnosis and therapy of malignant adrenal oncocytic neoplasm

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 882
Author(s):  
Agus Rizal Ardy Harlandy Hamid ◽  
Sahat Matondang ◽  
Agnes Stephanie Harahap ◽  
Ivan Putrantyo
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Adrenal Tumors ◽  
Case Presentation ◽  
Tumor Bed ◽  
Abdominal Ct Scan ◽  
History Of ◽  
Adrenal Masses ◽  
The Right ◽  
Oncocytic Neoplasm

Background: Adrenal masses are common incidental findings, most of which are benign and non-functional. Malignant adrenal tumors, however, differ from their benign counterpart and confer poor prognosis. In addition, the oncocytic variants of these tumors present challenges to clinicians owing to their unique biologic behavior and rarity. Case presentation: We present a case report of a 61-year-old male with a T2N0M0 adrenocortical oncocytic neoplasm of the right adrenal gland. The patient complained of worsening right upper quadrant abdominal pain and was diagnosed with a right adrenal mass after an abdominal CT-scan examination two weeks before. Subsequently, the patient underwent open adrenalectomy due to a history of abdominal surgery. Due to unique oncocytic biologic behavior, we used the Lin–Weiss–Bisceglia criteria to predict a malignancy instead of the Weiss system. We only found one malignant criterion, which showed a small tumor invasion on the vascular bed on one histopathological section. Thus, we diagnosed it as malignant adrenocortical oncocytic neoplasm. Furthermore, the PET Scan showed no residual mass or pathological metabolic activity on the tumor bed and metastatic sign. Conclusions: The diagnosis of the malignant oncocytic adrenal case is based on the histopathological criteria. Based on this case, we suggest a thorough histopathological examination to determine malignant criteria in adrenal neoplasm cases.

F.N.A.C. AS DIAGNOSTIC TOOL OF PAROTID TUMORS AND ASSOCIATED PITFALLS IN CORRELATION WITH HISTOPATHOLOGY

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Bhawana Pant ◽  
Sanjay Gaur ◽  
Prabhat Pant
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Clinical Information ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Cytological Diagnosis ◽  
Tertiary Referral Centre ◽  
Clear Cut ◽  
Parotid Tumors

F.NA.C has been used for ages as a safe and economical tool for fast preoperative diagnosis of parotid tumors. It has certain pitfall which sometimes leads to misdiagnosis and consequently it may have affect on treatment of the tumors. Keeping in view of the diverse classification of parotid tumors’ information from cytology should be combined with radiology as well as clinical diagnosis. Aim: To discuss some cases where there was discrepancy between cytological diagnosis and histopathological result and also suggest measures to improve the efficacy of F.N.A.C. Material and methods: The study includes 50 cases of parotid tumours who presented to the  department of ENT at Government medical college Haldwani which is a tertiary referral centre during 2009 to 2016. Only adult patients were included and inflammatory swelling were excluded from the study. All patients evaluated  Contrast enhanced computerized tomography(CECT) and  Magnetic resonance imaging (MRI) followed by Fine needle aspiration cytology .Preoperative diagnosis was made upon the findings of the above investigations and different types of  parotid surgeries  were done. . Final diagnosis was made on  histopathological  examination. Result :The most common tumour  came out to be pleomorphic adenoma (23 cases-46%) followed by mucoepidermoid carcinoma(12cases-24%). In ten  cases there was no clear cut  association between cytological diagnosis and final histopathological diagnosis. Conclusion: FNAC is highly sensitive and specific technique for diagnosis of many salivary gland swellings. FNAC can be used preoperatively to avoid unnecessary surgery and biopsy. Details of clinical information and radiologic features may help the pathologist to arrive at the appropriate diagnosis and reduce false interpretation. Pitfalls may also occur with improper technique of FNAC which can be overcome by proper caution.

Tuberculosis of the Gallbladder: An uncommon Case Report

2021 ◽  
Vol 15 (2) ◽  
pp. 106-107
Author(s):  
Swapan Kumar Biswas ◽  
Saiful Islam Khan ◽  
Muhammad Mofazzal Hossain
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Open Cholecystectomy ◽  
Chronic Cholecystitis ◽  
Computed Tomography Scan ◽  
Endemic Region ◽  
Uncommon Case ◽  
Tomography Scan

Isolated gall bladder tuberculosis (GBTB) is exceedingly rare even in an endemic region and is usually found as a GB mass in association with cholelithiasis. Confirmed preoperative diagnosis is very difficult, and most cases are diagnosed after cholecystectomy. We present a case of a 45-years-old woman who came with symptoms of chronic cholecystitis. Computed tomography scan revealed intraluminal gallbladder mass and cholelithiasis. The patient underwent open cholecystectomy and GBTB was diagnosed after histopathological examination. Histopathological examination should be done after all cholecystectomy operations. Faridpur Med. Coll. J. 2020;15(2): 106-107

Isolated Visceral Leishmaniasis Presenting as an Adrenal Cystic Mass

2000 ◽  
Vol 124 (10) ◽  
pp. 1553-1556
Author(s):  
David S. Brenner ◽  
Stephen C. Jacobs ◽  
Cinthia B. Drachenberg ◽  
John C. Papadimitriou
Keyword(s):  
Differential Diagnosis ◽  
Visceral Leishmaniasis ◽  
Chronic Inflammation ◽  
Adrenal Tumor ◽  
Left Kidney ◽  
Radical Resection ◽  
Cystic Mass ◽  
Suprarenal Mass ◽  
Adrenal Masses ◽  
Leishmania Amastigotes

Abstract A 69-year-old woman presented with a large left retroperitoneal suprarenal mass. Radical resection of the left kidney and the mass revealed a cystic adrenal tumor with a weight of 1500 g. Histologic examination showed that the cyst was composed mostly of partially organized clotted blood. The periphery of the mass consisted of a thin rim of cortical and medullary adrenal tissue with superimposed granulomatous chronic inflammation. The infectious nature of the process was manifested by the scattered intracellular and extracellular Leishmania amastigotes that were found throughout the lesion. The differential diagnosis of cystic adrenal masses and the unusual presentation of visceral leishmaniasis are discussed in this context.

scholarly journals Retroperitoneal pararenal castleman’s disease: a case report

2013 ◽  
Vol 3 (6) ◽  
pp. 509-511
Author(s):  
S Shrestha ◽  
U Nepal ◽  
N Lamichhane ◽  
P Chhetri
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Castleman’S Disease ◽  
Accurate Diagnosis ◽  
Renal Tumors ◽  
Unknown Etiology ◽  
Resected Specimen ◽  
Castleman's Disease ◽  
Vascular Type ◽  
Hyaline Vascular Type

Castleman’s diseas is a rare lymphoproliferative disorder of unknown etiology. We report a 28 years old woman with solitary Castleman’s disease in the left pararenal space. This case was diagnosed preoperatively as renal cell carcinoma. The patient underwent a radical nephrectomy with dissection of pararenal mass. Histopathological examination of the surgically resected specimen showed the hyaline vascular type of Castleman’s disease. A preoperative diagnosis of Castleman’s disease is difficult; therefore, a surgical resection and histopathological evaluation can provide an accurate diagnosis of tumor. Taking this case into consideration, we suggest that Castleman’s disease should be included in the differential diagnosis of renal tumors. DOI: http://dx.doi.org/10.3126/jpn.v3i6.9004 Journal of Pathology of Nepal (2013) Vol. 3, 509-511

scholarly journals Giant Gluteal Lipoma. A Case Report

2018 ◽  
Vol 1 (3) ◽  
pp. 213-216
Author(s):  
Carlos Manterola
Keyword(s):  
Case Report ◽  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Gluteal Region ◽  
Second Year

A case of gluteal lipoma treated at the Department of Surgery of the Hospital Clínico de la Universidad Mayor, Temuco, Chile is presented. The patient, a 42-year-old man, presented with a multilobulated tumor of soft parts located in the left gluteal region. The tumor was painless and was 22 cm in diameter. Complete exeresis of the lesion was performed. This was sent to histopathological examination, which confirmed the preoperative diagnosis of lipoma. The outcome was favorable, with no morbidity. The tomographic control at the second year of postoperative allowed us to verify the absence of recurrence.

Migratory neurocysticercosis mimicking a third ventricular colloid cyst

2001 ◽  
Vol 95 (1) ◽  
pp. 122-123 ◽  
Author(s):  
Steven D. Wray ◽  
Thomas L. Ellis ◽  
Sabatino Bianco
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Third Ventricle ◽  
Colloid Cyst ◽  
Foramen Of Monro ◽  
Radiographic Findings ◽  
Content Type ◽  
Intracranial Lesions ◽  
Microsurgical Approach ◽  
Mental Decline

✓ The authors report on a case of solitary neurocysticercosis located in the anterior third ventricle of a 21-year-old Hispanic man who presented with progressive headache, nausea, and mental decline. The appearance of the lesion on computerized tomography and magnetic resonance studies was typical of that of a colloid cyst, which was the presumptive preoperative diagnosis. A transcortical-transventricular microsurgical approach was used, and inspection of the anterior third ventricle via the ipsilateral foramen of Monro revealed no lesion. Inspection of the floor of the ipsilateral lateral ventricle revealed the intact cyst, which had migrated since the preoperative studies had been obtained. The lesion was removed intact, and histopathological examination confirmed the diagnosis of neurocysticercosis. The authors review the radiographic findings in this case and further illustrate the potential for neurocysticercosis to masquerade as other intracranial lesions.

scholarly journals Tuberculosis of the Clivus

2016 ◽  
Vol 06 (01) ◽  
pp. 072-075
Author(s):  
Vijay Joshi ◽  
Shirish Valsangkar ◽  
Ashwin Valsangkar ◽  
Anish Dekhne ◽  
Satish Nivargi ◽  
...  
Keyword(s):  
Trigeminal Neuralgia ◽  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Antitubercular Therapy ◽  
Neurological Symptoms ◽  
Contrast Administration ◽  
Appropriate Treatment

AbstractThe rarity of the tubercular involvement of the clivus makes the preoperative diagnosis difficult. We report a case of a 40-year-old man who presented with right-sided trigeminal neuralgia without any other neurological symptoms or deficits. Postcontrast images showed a dural-based lesion in the region of the clivus which was isointense on T1 images and hypointense on T2 images and the lesion was enhancing after contrast administration suggestive of a tumor. The patient underwent surgical excision of the lesion and the histopathological examination was suggestive of tuberculosis. The patient completed the course of antitubercular therapy and recovered well. Tuberculosis of the clivus region runs an indolent course and following appropriate treatment these patient do well.

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