scholarly journals Prevalence and predictors of medication non-adherence among patients with multimorbidity: A systematic review protocol

2019 ◽  
Vol 2 ◽  
pp. 29
Author(s):  
Louise Foley ◽  
James Larkin ◽  
Richard Lombard-Vance ◽  
Andrew W. Murphy ◽  
Gerard J. Molloy
Keyword(s):  
Systematic Review ◽  
Full Text ◽  
Chronic Conditions ◽  
Data Extraction ◽  
Meta Analysis ◽  
Intervention Development ◽  
Evidence Base ◽  
Multiple Chronic Conditions ◽  
Review Protocol ◽  
Form Quality

Introduction: Patients with multimorbidity are expected to adhere to complex medication regimens in order to manage their multiple chronic conditions. It has been reported the likelihood of adherence decreases as patients are prescribed more medications. Much medication adherence research to date is dominated by a single-disease focus, which is at odds with the rising prevalence of multimorbidity and may artificially underestimate the complexity of managing chronic illness. This review aims to describe the prevalence of medication non-adherence among patients with multimorbidity, and to identify potential predictors of non-adherence in this population. Methods: A systematic review will be conducted and reported according to PRISMA guidelines. PubMed, EMBASE, CINAHL and PsycINFO will be searched using a predefined search strategy from 2009–2019. Quantitative studies will be considered eligible for review if prevalence of medication non-adherence among adults with two or more chronic conditions is reported. Studies will be included in the review if available in English full text. Titles and abstracts will be screened by single review, with 20% of screening cross-checked by a second reviewer. Full-text articles will be screened by two independent reviewers, noting reasons for exclusions. Data extraction will be performed using a predefined extraction form. Quality and risk of bias assessment will be conducted using criteria for observational studies outlined by Sanderson et al. (2007). A narrative synthesis and, if feasible, meta-analysis will be conducted. Discussion: By exploring medication non-adherence from a multimorbidity perspective, the review aims to inform an evidence base for intervention development which accounts for the rising prevalence of patients with multiple chronic conditions.  Study registration: The systematic review is prospectively registered in PROSPERO (CRD42019133849); registered on 12 June 2019.

scholarly journals Prevalence and predictors of medication non-adherence among patients with multimorbidity: A systematic review protocol

2021 ◽  
Vol 2 ◽  
pp. 29
Author(s):  
Louise Foley ◽  
James Larkin ◽  
Richard Lombard-Vance ◽  
Andrew W. Murphy ◽  
Gerard J. Molloy
Keyword(s):  
Systematic Review ◽  
Full Text ◽  
Chronic Conditions ◽  
Data Extraction ◽  
Meta Analysis ◽  
Intervention Development ◽  
Evidence Base ◽  
Multiple Chronic Conditions ◽  
Review Protocol ◽  
Form Quality

Introduction: Patients with multimorbidity are expected to adhere to complex medication regimens in order to manage their multiple chronic conditions. It has been reported the likelihood of adherence decreases as patients are prescribed more medications. Much medication adherence research to date is dominated by a single-disease focus, which is at odds with the rising prevalence of multimorbidity and may artificially underestimate the complexity of managing chronic illness. This review aims to describe the prevalence of medication non-adherence among patients with multimorbidity, and to identify potential predictors of non-adherence in this population. Methods: A systematic review will be conducted and reported according to PRISMA guidelines. PubMed, EMBASE, CINAHL and PsycINFO will be searched using a predefined search strategy from 2009–2019. Quantitative studies will be considered eligible for review if prevalence of medication non-adherence among adults with two or more chronic conditions is reported. Studies will be included in the review if available in English full text. Titles and abstracts will be screened by single review, with 20% of screening cross-checked by a second reviewer. Full-text articles will be screened by two independent reviewers, noting reasons for exclusions. Data extraction will be performed using a predefined extraction form. Quality and risk of bias assessment will be conducted using criteria for observational studies outlined by Sanderson et al. (2007). A narrative synthesis and, if feasible, meta-analysis will be conducted. Discussion: By exploring medication non-adherence from a multimorbidity perspective, the review aims to inform an evidence base for intervention development which accounts for the rising prevalence of patients with multiple chronic conditions.  Study registration: The systematic review is prospectively registered in PROSPERO (CRD42019133849); registered on 12 June 2019.

scholarly journals Interpersonal psychotherapy for perinatal women: a systematic review and meta-analysis protocol

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Katherine S. Bright ◽  
Elyse M. Charrois ◽  
Muhammad Kashif Mughal ◽  
Abdul Wajid ◽  
Deborah McNeil ◽  
...  
Keyword(s):  
Systematic Review ◽  
Full Text ◽  
Data Extraction ◽  
Meta Analysis ◽  
Mode Of Delivery ◽  
Well Being ◽  
Interpersonal Psychotherapy ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Perinatal Women

Abstract Background Interpersonal psychotherapy (IPT) is an intervention that has established efficacy in the prevention and treatment of depressive disorders. Previous systematic reviews have not evaluated the effectiveness of IPT on symptoms of stress, anxiety, depression, quality of life, relationship satisfaction/quality, social supports, and an improved psychological sense of well-being. There is limited data regarding factors that moderate and mediate the effectiveness of IPT including the timing of the intervention or the mode of delivery of IPT intervention. The objective of this systematic review and meta-analysis is to evaluate the effectiveness, feasibility, and acceptability of IPT interventions to treat perinatal psychological distress and to summarize the evidence on predictors, mediators, and moderators of IPT. Methods We will include peer-reviewed studies that recruited perinatal women. The search strategy will involve the following databases: MEDLINE (Ovid), EMBASE (Ovid), PsycINFO (Ovid), Cochrane Central Register of Controlled Trials (Ovid), CINAHL with Full Text (EBSCO), Social Work Abstracts (EBSCO), SocINDEX with Full Text (EBSCO), Academic Search Complete (EBSCO), Family & Society Studies Worldwide (EBSCO), Family Studies Abstracts (EBSCO), and Scopus. Study inclusion criteria include (1) randomized controlled trials, quasi-experimental studies, and pre-post studies that evaluated the effectiveness of IPT; (2) qualitative studies that evaluated feasibility and acceptability of IPT; (3) study sample included and analyzed perinatal women; and (4) publication language was English. Using pilot-tested screening and data extraction forms, two reviewers will independently review studies in three steps: (1) abstract/title screening, (2) full-text screening of potentially accepted studies, and (3) data extraction of accepted studies. Disagreements will be resolved by a third reviewer. Studies will be aggregated for meta-synthesis and meta-analysis should the data allow for this. Two independent reviewers will grade methodological quality. Discussion Findings from this review will inform future development and implementation of IPT intervention research for perinatal women. Identifying key factors of successful IPT interventions will inform intervention design and adaptation of IPT interventions to increase the likelihood that perinatal women will engage in and benefit from IPT interventions. This review will also identify key considerations for increasing the effectiveness of IPT interventions during the perinatal period. Systematic review registration PROSPERO CRD42019114292

scholarly journals Use of Dental Practices for the Identification of Adults With Undiagnosed Type 2 Diabetes Mellitus or Nondiabetic Hyperglycemia: Protocol for a Systematic Review (Preprint)

2018 ◽  
Author(s):  
Zehra Yonel ◽  
Praveen Sharma ◽  
Laura J Gray
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Data Extraction ◽  
Meta Analysis ◽  
Evidence Base ◽  
Statistical Analysis Plan ◽  
Dental Services

BACKGROUND Type 2 diabetes mellitus (T2DM) is a growing global health burden and is expected to affect more than 590 million people by the year 2035. Evidence exists to demonstrate that dental settings have been used for risk assessment and identification of individuals who may be at high risk for T2DM or who may already unknowingly have the condition. OBJECTIVE This protocol aims to outline the methodology that will be undertaken to synthesize the literature relating to the use of primary care (nonhospital-based) dental services for the identification of undiagnosed T2DM or prediabetes—often termed nondiabetic hyperglycemia—in adult patients. METHODS This paper outlines the protocol that will be followed to conduct a systematic review and meta-analysis of the available literature. The protocol outlines the aims, objectives, search strategy, data extraction and data management methods, as well as the statistical analysis plan. The Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines were followed in developing the protocol as were elements of the Cochrane handbook. RESULTS We expect the systematic review to be completed within 18 months of publication of this protocol and expect to see a high degree of heterogeneity in the existing literature. CONCLUSIONS This review is of importance as it will synthesize the existing evidence base and inform future studies in the field. Following the publication of the protocol, the review will be registered on Prospective Register of Systematic Reviews. Following the completion of the review, results will be published in a suitable peer-reviewed journal. INTERNATIONAL REGISTERED REPOR PRR1-10.2196/11843

scholarly journals Implementing Digital Storytelling for Health-Related Outcomes in Older Adults: Protocol for a Systematic Review

10.2196/15512 ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. e15512
Author(s):  
Jennifer Stargatt ◽  
Sunil Bhar ◽  
Jahar Bhowmik ◽  
Abdullah Al Mahmud
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Digital Storytelling ◽  
Data Extraction ◽  
Meta Analysis ◽  
Evidence Base ◽  
Eligibility Criteria ◽  
Psychological Comorbidities ◽  
Health Related

Background The number of older adults is increasing rapidly worldwide. Older adults face a unique set of challenges and may experience a range of psychological comorbidities. Advances in multimedia technology have allowed for digital storytelling to be utilized as an intervention for health-related outcomes. Objective The primary aim of the proposed systematic review is to examine the reported health-related outcomes for older adults engaged in digital storytelling. The review also aims to examine the methods associated with digital storytelling, characteristics of digital story products, and implementational considerations. Methods This protocol adheres to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols. We will systematically search selected electronic databases to identify studies that meet our eligibility criteria. From the included studies, data will be extracted and synthesized using a narrative approach and summarized in tables. The methodological quality of the included studies will be assessed using the Mixed Methods Appraisal Tool. Results Systematic searches, data extraction and analysis, and writing of the systematic review are expected to be completed by the end of 2019. Conclusions The proposed systematic review will summarize the existing studies using digital storytelling to improve health-related outcomes for older adults. Results from this review will provide an evidence base for the development of digital storytelling interventions that are effective and implementable with older adults. International Registered Report Identifier (IRRID) PRR1-10.2196/15512

scholarly journals A systematic review investigating patient knowledge and awareness on the association between oral health and their systemic condition

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sabrina Akl ◽  
Madusha Ranatunga ◽  
Sharron Long ◽  
Ernest Jennings ◽  
Alan Nimmo
Keyword(s):  
Systematic Review ◽  
Oral Health ◽  
Health Education ◽  
Respiratory Disease ◽  
Bone Disease ◽  
Chronic Conditions ◽  
Data Extraction ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Common Source

Abstract Background The prevalence of the oral-systemic relationship has accounted for potentially preventable chronic conditions and morbidity worldwide. Health literacy is a large contributing factor. This systematic review investigates the knowledge and awareness of patients with major systemic conditions, regarding the oral associations to their condition. Methods Electronic databases including Medline (Ovid), CINAHL, The Cochrane Library, Web of Science, Informit Health Databases and Scopus were searched. All articles from 2011 to 2020, investigating knowledge of the oral-systemic link, of adult patients with the following major system conditions were searched: diabetes mellitus (DM), respiratory disease, cardiovascular disease (CVD), pregnancy and bone disease. Two independent reviewers completed screening, data extraction and quality assessment. A synthesis without meta-analysis was conducted. Twenty-four studies, from 14 different countries, were included in the systematic review. Results Analysis showed that globally, patients with major systemic conditions have poor knowledge and awareness (< 50%) of the oral health associations to their condition. Improvements in health education are particularly necessary for patients with heart disease, bone disease and diabetes. Dentists and the media were the most common source of information. There were no relevant studies investigating the knowledge of patients with respiratory disease. Conclusion To improve the global burden of preventable chronic conditions, it is essential to address inequalities in the dissemination of health education to at-risk populations. Improvements in patient education rely on an increase in patient-practitioner communication on the oral-systemic link, implementation of oral health educational programs and greater interdisciplinary collaboration.

scholarly journals A Systematic Review of Interleaving as a Concept Learning Strategy

2019 ◽  
Vol 2 ◽  
pp. 1-7
Author(s):  
Jonathan Firth ◽  
Ian Rivers ◽  
James Boyle
Keyword(s):  
Systematic Review ◽  
Learning Strategy ◽  
Data Extraction ◽  
Meta Analysis ◽  
Evidence Base ◽  
Learning And Teaching ◽  
Effective Learning ◽  
Memory Functioning ◽  
Effective Use ◽  
Quality Learning

Education Scotland’s (2018) framework for interventions for equity supporting the Scottish Attainment Challenge highlights the promotion of high quality learning and the effective use of evidence and data. This study protocol outlines the methodology of a systematic review of the literature into the use of interleaving to facilitate the effective learning and teaching of new concepts. The systematic review has been pre-registered with PROSPERO, an international database of prospectively registered systematic reviews (https://www.crd.york.ac.uk/PROSPERO/). The review will investigate whether presenting examples of to-be-learned concepts in an interleaved order is a more effective learning strategy than presenting examples blocked by topic, in terms of learners' ability to remember examples and to transfer learning to novel examples. Interleaving is widely recommended as an evidence-based approach to teaching with considerable potential as a strategy for learners experiencing difficulties in working memory functioning and conceptual learning, but to date there has not been a comprehensive review of the evidence base. The review will address this gap. It will synthesize primary research studies from the past decade, investigate boundary conditions and variables that interact with interleaving, and will include a meta-analysis of recent studies. This protocol provides the details of the rationale of the review, and details the inclusion criteria and approaches to data extraction.

scholarly journals Multiple Chronic Conditions and Functional Outcome after Ischemic Stroke: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 54 (3) ◽  
pp. 205-213 ◽  
Author(s):  
Xiaqing Jiang ◽  
Lewis B. Morgenstern ◽  
Christine T. Cigolle ◽  
Edward S. Claflin ◽  
Lynda D. Lisabeth
Keyword(s):  
Systematic Review ◽  
Ischemic Stroke ◽  
Functional Outcome ◽  
Chronic Conditions ◽  
Meta Analysis ◽  
Multiple Chronic Conditions

scholarly journals The Prevalence and Incidence of Dementia Due to Alzheimer’s Disease: a Systematic Review and Meta-Analysis

2016 ◽  
Vol 43 (S1) ◽  
pp. S51-S82 ◽  
Author(s):  
Kirsten M. Fiest ◽  
Jodie I. Roberts ◽  
Colleen J. Maxwell ◽  
David B. Hogan ◽  
Eric E. Smith ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Criteria ◽  
Full Text ◽  
Data Extraction ◽  
Meta Analysis ◽  
Community Settings ◽  
Healthcare Needs ◽  
The Impact

AbstractBackgroundUpdated information on the epidemiology of dementia due to Alzheimer’s disease (AD) is needed to ensure that adequate resources are available to meet current and future healthcare needs. We conducted a systematic review and meta-analysis of the incidence and prevalence of AD.MethodsThe MEDLINE and EMBASE databases were searched from 1985 to 2012, as well as the reference lists of selected articles. Included articles had to provide an original population-based estimate for the incidence and/or prevalence of AD. Two individuals independently performed abstract and full-text reviews, data extraction and quality assessments. Random-effects models were employed to generate pooled estimates stratified by age, sex, diagnostic criteria, location (i.e., continent) and time (i.e., when the study was done).ResultsOf 16,066 abstracts screened, 707 articles were selected for full-text review. A total of 119 studies met the inclusion criteria. In community settings, the overall point prevalence of dementia due to AD among individuals 60+ was 40.2 per 1000 persons (CI95%: 29.1-55.6), and pooled annual period prevalence was 30.4 per 1000 persons (CI95%: 15.6-59.1). In community settings, the overall pooled annual incidence proportion of dementia due to AD among individuals 60+ was 34.1 per 1000 persons (CI95%: 16.4-70.9), and the incidence rate was 15.8 per 1000 person-years (CI95%: 12.9-19.4). Estimates varied significantly with age, diagnostic criteria used and location (i.e., continent).ConclusionsThe burden of AD dementia is substantial. Significant gaps in our understanding of its epidemiology were identified, even in a high-income country such as Canada. Future studies should assess the impact of using such newer clinical diagnostic criteria for AD dementia such as those of the National Institute on Aging–Alzheimer’s Association and/or incorporate validated biomarkers to confirm the presence of Alzheimer pathology to produce more precise estimates of the global burden of AD.

scholarly journals Coccydynia – the efficacy of available treatment options: a systematic review protocol

2021 ◽  
Author(s):  
Mads Moss Jensen ◽  
Gustav Østerheden Andersen ◽  
Stefan Milosevic ◽  
Mikkel Østerheden Andersen ◽  
Leah Carreon ◽  
...  
Keyword(s):  
Systematic Review ◽  
Web Of Science ◽  
Data Extraction ◽  
Meta Analysis ◽  
Treatment Options ◽  
Bibliographic Databases ◽  
Painful Condition ◽  
Review Protocol ◽  
Background Context

Abstract Background context: Coccydynia is a painful condition which may severely impair quality of life in affected patients. Treatment of coccydynia is a field of interest with limited knowledge. The objective of this study is to evaluate the efficacy of current available treatments for coccydynia in adults, by systematically reviewing existing original peer-reviewed publications according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.Methods/design: A systematic literature search will be conducted in EMBASE.com, PubMed.com, Scopus and Web of Science bibliographic databases from their inception to January 17th, 2020, alongside a search for published studies and Epubs ahead of print in journals with relevance to spine surgery. Studies eligible for inclusion are original peer-reviewed papers addressing treatment of chronic coccydynia in adults. The articles will be screened by two authors independently, involving a third author in case of disagreement. Quality assessment and data extraction will be conducted using Covidence software. A meta-analysis will be conducted given that data is suitable.Discussion: This systematic review and meta-analysis may contribute to the existing knowledge on the efficacy of treatment options for coccydynia.Systematic review registration: PROSPERO submission-ID: 166379

Sign in / Sign up

Export Citation Format

Share Document