scholarly journals Relation between Lineal Energy Distribution and Relative Biological Effectiveness for Photon Beams according to the Microdosimetric Kinetic Model

2011 ◽  
Vol 52 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Hiroyuki OKAMOTO ◽  
Tatsuaki KANAI ◽  
Yuki KASE ◽  
Yoshitaka MATSUMOTO ◽  
Yoshiya FURUSAWA ◽  
...  
Keyword(s):  
Kinetic Model ◽  
Energy Distribution ◽  
Relative Biological Effectiveness ◽  
Photon Beams ◽  
Lineal Energy ◽  
Biological Effectiveness

WE-H-BRA-01: BEST IN PHYSICS (THERAPY): Nano-Dosimetric Kinetic Model for Variable Relative Biological Effectiveness of Proton and Ion Beams

2016 ◽  
Vol 43 (6Part42) ◽  
pp. 3842-3842 ◽  
Author(s):  
R Abolfath ◽  
L Bronk ◽  
Y Helo ◽  
J Schuemann ◽  
U. Titt ◽  
...  
Keyword(s):  
Kinetic Model ◽  
Relative Biological Effectiveness ◽  
Ion Beams ◽  
Biological Effectiveness

Estimations of relative biological effectiveness of secondary fragments in carbon ion irradiation of water using CR‐39 plastic detector and microdosimetric kinetic model

2019 ◽  
Vol 47 (2) ◽  
pp. 781-789 ◽  
Author(s):  
Yoshiyuki Hirano ◽  
Satoshi Kodaira ◽  
Hikaru Souda ◽  
Kohei Osaki ◽  
Masami Torikoshi
Keyword(s):  
Kinetic Model ◽  
Relative Biological Effectiveness ◽  
Ion Irradiation ◽  
Carbon Ion ◽  
Plastic Detector ◽  
Biological Effectiveness

TU-A-BRE-01: The Relative Biological Effectiveness of Proton Beams Relative to Photon Beams

2014 ◽  
Vol 41 (6Part26) ◽  
pp. 445-445
Author(s):  
H Paganetti ◽  
R Stewart ◽  
A Carabe-Fernandez
Keyword(s):  
Relative Biological Effectiveness ◽  
Photon Beams ◽  
Proton Beams ◽  
Biological Effectiveness

A modified microdosimetric kinetic model for relative biological effectiveness calculation

2017 ◽  
Vol 63 (1) ◽  
pp. 015008 ◽  
Author(s):  
Yizheng Chen ◽  
Junli Li ◽  
Chunyan Li ◽  
Rui Qiu ◽  
Zhen Wu
Keyword(s):  
Kinetic Model ◽  
Relative Biological Effectiveness ◽  
Biological Effectiveness

Relative biological effectiveness study of Lipiodol based on microdosimetric-kinetic model

2018 ◽  
Vol 46 ◽  
pp. 89-95 ◽  
Author(s):  
Daisuke Kawahara ◽  
Hisashi Nakano ◽  
Shuichi Ozawa ◽  
Akito Saito ◽  
Tomoki Kimura ◽  
...  
Keyword(s):  
Kinetic Model ◽  
Relative Biological Effectiveness ◽  
Effectiveness Study ◽  
Biological Effectiveness

scholarly journals Radiobiological effects of the interruption time in radiation therapy with photon beams based on the microdosimetric kinetic model

2020 ◽  
Author(s):  
Hisashi Nakano ◽  
Daisuke Kawahara ◽  
Satoshi Tanabe ◽  
Satoru Utsunomiya ◽  
Takeshi Takizawa ◽  
...  
Keyword(s):  
Kinetic Model ◽  
Absorbed Dose ◽  
Cancer Cell Line ◽  
Heavy Ion ◽  
Lung Cancer Cell Line ◽  
Photon Beams ◽  
Constant Dose ◽  
Biological Effectiveness ◽  
Radiobiological Effects ◽  
Set Up

Abstract Background: We investigated the effect of the interruption time on the radiobiological effectiveness with photon beams based on a modified microdosimetric kinetic model. Background: The interruption time is used is that irradiation interruption occurs at sites and operations such as the gantry, collimator, couch rotation, and patient set-up in radiotherapy. However, the effect of interruption time on photon beams for tumor cells is little evaluated.Methods: The dose-mean lineal energy yD (keV/µm) of 6 MV photon beams was calculated by the particle and heavy ion transport system (PHITS). We set the absorbed dose to 2 or 8 Gy, and the interruption time (τ) was set to 1, 3, 5, or 10 min. The biological parameters values were acquired from a human non-small cell lung cancer cell line (NCI-H460) for the mMK model. We used two-field and four-field irradiation with a constant dose rate (3 Gy/min); the photon beams were paused for interruption time τ. We calculated the relative biological effectiveness (RBE) to evaluate the interruption time's effect compared with photon beams that were not interrupted as a reference. Results: The RBE with four-field irradiation for 8 Gy was decreased to 0.997, 0.992, 0.987, and 0.975 for τ = 1, 3, 5, and 10 min, respectively. The decrease in the RBE was within 3% compared with the non-interrupted photon beams. Conclusions: The effect of RBE was decreased by increasing the interruption time, indicating that an escalation of the prescribed dose might be necessary when the interruption time was large.

scholarly journals Estimation of relative biological effectiveness for boron neutron capture therapy using the PHITS code coupled with a microdosimetric kinetic model

2014 ◽  
Vol 56 (2) ◽  
pp. 382-390 ◽  
Author(s):  
Hironori Horiguchi ◽  
Tatsuhiko Sato ◽  
Hiroaki Kumada ◽  
Tetsuya Yamamoto ◽  
Takeji Sakae
Keyword(s):  
Kinetic Model ◽  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Relative Biological Effectiveness ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Biological Effectiveness
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