scholarly journals The Radioprotective Effect against Gamma-Irradiation of Methylene Blue in the Rat with Reference to Serum Enzymes and Pancreatic Protein Fractions Examined by Isoelectric Focussing

1975 ◽  
Vol 16 (4) ◽  
pp. 211-223 ◽  
Author(s):  
SE O CHUNG ◽  
SANG YUL NAM

2020 ◽  
Author(s):  
Marina Yu. Kopaeva ◽  
Irina B. Alchinova ◽  
Mikhail V. Nesterenko ◽  
Anton B. Cherepov ◽  
Marina S. Demorzhi ◽  
...  


2020 ◽  
Vol 159 ◽  
pp. 109091
Author(s):  
Mehrsa Majdaeen ◽  
Amin Banaei ◽  
Razzagh Abedi-Firouzjah ◽  
Kourosh Ebrahimnejad Gorji ◽  
Gholamreza Ataei ◽  
...  


1974 ◽  
Vol 29 (9-10) ◽  
pp. 647-649
Author(s):  
Roberto Badiello ◽  
Enrico Gattavecchia ◽  
Mario Mattii ◽  
Maurizio Tamba

Abstract This paper deals with a study of some tests in rats in vivo after gamma irradiation in the presence and in the ab­ sence of selenourea. The factors considered were the total protein content, the protein pattern, and some serum enzymes, like GOT, GPT and AP. The result shows that the preadministration of selenourea modifies fovourably the changes induced by ionizing radiation



Author(s):  
Binguo Zheng ◽  
Chunguang Li ◽  
Lingyan Jiang ◽  
Lizheng Liang ◽  
Weigong Pen ◽  
...  


2012 ◽  
Vol 4 (1) ◽  
pp. 197-206 ◽  
Author(s):  
Amit Kumar Dixit ◽  
Deepti Bhatnagar ◽  
Vineet Kumar ◽  
D. Chawla ◽  
K. Fakhruddin ◽  
...  


2007 ◽  
Vol 22 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Lal Bhatia ◽  
Ajay Gaur ◽  
Avadhesh Sharma

The radioprotective effects of an acute administration of the isoflavone genistein (4?, 5, 7-trihydroxyflavone), have been investigated in the present study. Male mice were administered with different doses (100, 200, 300, and 400 mg/kg body weight) of genistein 24 hours prior to 8 Gy gamma irradiation and the 200 mg/kg dose of genistein was determined to offer the maximum survivability and was used as an optimum dose for further experimentation. The 0.5 ml dose of genistein (200 mg/kg) was administered intraperitoneally to 2 different groups of mice, 15 minutes and 24 hours prior to gamma irradiation. In the mice treated with genistein with the optimum dose 24 hours before irradiation, a significant increase in 30 day survival has been recorded in contrast to the mice treated with genistein 15 minutes before the irradiation. The longer survivability (i. e. 20% for a period of more than 30 days) has been observed in the 24 hour group as compared to that of 15 minutes (i. e. 20% for 22 days). Although the radioprotective effect of genistein was evident in both groups, it was of greater magnitude in the group with a longer interval, indicating thereby an efficacy with longer retention with the possible minimum toxicity, unlike hitherto known other radioprotective agents.





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