scholarly journals An Unusual Case of Pyogenic Liver Abscess Caused by Community-acquired Methicillin-Resistant Staphylococcus aureus

2020 ◽  
Vol 8 (2) ◽  
pp. 53-55
Author(s):  
Jeffrey Song ◽  
Tariq Sharman ◽  
Khubaib Gondal
2021 ◽  
Vol 8 (40) ◽  
pp. 3470-3476
Author(s):  
Navya Sree Manugu ◽  
Narayana Lunavath ◽  
Ramu Pedada

BACKGROUND Amoebic liver abscess is the commonest extra intestinal site of invasive amoebiasis which mainly affects infants and young children. The incidence of pyogenic liver abscess is much higher among children in developing countries than those in developed countries. Diagnosis of liver abscess can be challenging and is often delayed; a high index of suspicion is necessary in children with risk factors. Children have unique set of predisposing causes for liver abscesses. The purpose of this study was to assess the clinical, demographic, and etiological profile of liver abscess in children between 1 month to 12 years of age. METHODS This is a prospective observational study conducted in the Department of Pediatrics, Chacha Nehru Bal Chikistalaya (An Autonomous Institute under Govt. of NCT (National Capital Territory) of Delhi, affiliated to University of Delhi), Delhi from July 2016 to August 2017. All children aged 1 month to 12 years admitted with liver abscess (included consecutively) were enrolled after considering inclusion and exclusion criteria. Written and informed consent was taken from parents/guardians of children aged less than 7 years. Informed assent was taken from children aged more than 7 years, along with written and informed consent from their parents/guardians. Their clinical characteristics, radiological features and laboratory data were analysed. RESULTS Most common age group suffering from liver abscess was 5 - 10 years with male preponderance. Majority of the children belonged to lower socio-economic class and half of them were suffering from malnutrition. Most common clinical presentation of children suffering from liver abscess was fever with pain abdomen and tender hepatomegaly. Majority of the children had leucocytosis, high level of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Deranged liver function test with coagulopathy was noted in more than half of the children suffering from liver abscess. Commonest bacterial pathogen was methicillin resistant Staphylococcus aureus followed by Salmonella typhi, Stenotrophomonas maltophilia, coagulase negative Staphylococcus aureus and Staphylococcus hominis. Entamoeba histolytica is a common parasitic agent causing liver abscess in children. CONCLUSIONS Liver abscess should be considered in children presenting with fever and abdominal pain. Most cases involve a single lesion on right lobe of the liver. Methicillin resistant Staphylococcus aureus followed by Salmonella typhi are the two most common pathogens. KEYWORDS Paediatric Liver Abscess, Amoebic Liver Abscess, Pyogenic Liver Abscess, Children


2017 ◽  
Vol 5 (1) ◽  
pp. 232470961769312

Cherian J, Singh R, Varma M, Vidyasagar S, Mukhopadhyay C. Community-acquired methicillin-resistant pyogenic liver abscess: a case report. J Investig Med High Impact Case Rep. 2016;4(3):1-3. doi: 10.1177/2324709616660576


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Gargi Patel ◽  
Neha Shah ◽  
Roopali Sharma

Pyogenic liver abscess (PLA) is a potentially fatal disease.Klebsiella pneumoniae(K. pneumoniae) has replacedEscherichia coli(E. coli) as the predominant causative organism for pyogenic liver abscess. Over the years a unique form of community-acquired invasiveK. pneumoniaeinfection of the liver has been well described in Southeast Asia. This has recently been linked to a virulent hypermucoviscousK. pneumoniaephenotype and to a specific genotype,rmpApositive. To our knowledge, we report the first case of PLA with bacteremia and meningitis in a Guyanese patient with the presence ofrmpA-positiveK. pneumoniaewith laboratory evidence in North America.


2016 ◽  
Vol 53 (3) ◽  
pp. 270-275 ◽  
Author(s):  
D. Antolová ◽  
D. Hudáčková ◽  
M. Fecková ◽  
A. Feketeová ◽  
M. Szilágyová

SummaryPyogenic liver abscess is an uncommon but important and potentially life-threatening disease that occurs whenever there is failure of clearance of an infection in the liver. Work presents a rare case of pyogenic liver abscess with confirmed bacterial aetiology ofStaphylococcus aureus, subsequently confirmedEchinococcus multilocularisand suspectedMycobacterium tuberculosisliver infection in 6 years old child. Moreover, several other parasitic diseases were recorded. According to clinical presentation of diseases, it could be supposed that liver impairment caused by alveolar echinococcosis and potentially also byM. tuberculosiscould be the predisposition site for the capture ofStaphylococcus aureusin altered liver tissues during its haematogenous spreading, and thus contributed to the development and subsequent clinical presentation of pyogenic liver abscess. The presence of three different aetiological agents complicated the diagnostic process as well as the therapy of the patient and made her prognosis uncertain. Proper diagnosis of multiloculated liver abscesses, with echinococcosis and hepatic tuberculosis considered in the differential diagnosis, is therefore crucial to administration of early and appropriate treatment.


2014 ◽  
Vol 96 (2) ◽  
pp. e13-e16
Author(s):  
AJL Jowett ◽  
SWF Middleton ◽  
MC Quaye ◽  
H Chesterfield ◽  
I Lasrado ◽  
...  

We present an unusual case of haematogenous osteomyelitis in the diaphysis of the tibia of an adult leading to a subacute presentation with an extracortical abscess. Fluid from the abscess grew methicillin resistant Staphylococcus aureus (MRSA) on culture; MRSA with the same antibiogram had been grown from the patient’s blood seven years earlier following a bowel resection. Drainage of the abscess and curettage of the bone lesion together with appropriate antibiotic therapy led to resolution of the osteomyelitis.


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