scholarly journals CHARACTERISTICS OF DISTURBANCES IN NEUROPHYSIOLOGICAL AND PSYCHO-EMOTIONAL STATUS OF PATIENTS WITH VIBRATION DISEASE IN THE POSTEXPOSURE PERIOD

2016 ◽  
Vol 1 (6) ◽  
pp. 98-102
Author(s):  
Лахман ◽  
Oleg Lakhman ◽  
Катаманова ◽  
Elena Katamanova ◽  
Кулешова ◽  
...  
Keyword(s):  
Exposure Period ◽  
Control Group ◽  
Bioelectrical Activity ◽  
Length Of Service ◽  
Local Vibration ◽  
Afferent Pathways ◽  
Post Exposure ◽  
Vibration Disease ◽  
Upper And Lower Extremities ◽  
The Mean

The article presents the results of the studies of the central and peripheral nervous systems, psychoemotional status of patients with vibration disease associated with exposure to the local vibration in the post-exposure period. The stud-ies were performed in patients with vibration disease (n=18) who do not work in the contact with the local vibration at present. The mean age of the patients was 50.7±5.4years, the mean length of service in the contact with local vibration –17.9±2.8years, the mean post-exposure period – 5.2±2.2years. 30male persons having no contact with industrial hazard were comprised the control group. Electroencephalography, electroneuromyography, recording of somatosensory evoked potentials were carried out and patients’ personality peculiarities were studied. The changes of the brain bioelectrical activity, disorders of the autonomic and afferent regulation of the cerebral level, dysfunc-tion in diencephalic structures, disorders of the subcortical and cortical structures of the central afferent pathways; demyelization of the peripheral nerves of the upper and lower extremities were set in patients with vibration disease in the post-exposure period. Psychological studies have shown that patients with vibration disease in the post-exposure period preserve such psychological peculiarities as neuroticism manifested with inner tension, nervousness and chronic feeling of discomfort; depressive tendencies being a sign of the existing distress, and anxious-hypochondriac features in the structure of personality traits. All of the above result in formation of stable uncompensated clinical conditions observed in patients with vibration disease caused by local vibration exposure, even after the termination of harmful production factors.

Psychological features of patients with vibration disease in the post-contact period

2019 ◽  
pp. 278-283 ◽  
Author(s):  
Marina V. Kuleshova ◽  
Vladimir A. Pankov
Keyword(s):  
Cognitive Strategies ◽  
Exposure Period ◽  
Psychological Status ◽  
Contact Period ◽  
Behavioral Strategies ◽  
Local Vibration ◽  
Post Exposure ◽  
Vibration Disease ◽  
Wide Range ◽  
Personal Anxiety

Introduction. Vibration disease (VD) occupies a leading place in the overall structure of chronic occupational pathology. High sensitivity to environmental influences, instability of emotional state, hypochondriac features, rigid stereotype of behavior, propensity to depressive states, dissatisfaction with the state which is often considered by patients as disability are revealed in patients with VD. However, there is almost no information about the psychoemotional state of patients in the post-exposure period.The aim of the study was to study the psychological status of patients with VD in the post-exposure period.Materials and methods. The studies were performed in patients with VD from exposure to local vibration in a connected sample (n=20), including the post-exposure period. For the evaluation of psychological status were used: «Scale of assessment of the level of reactive and personal anxiety», an adapted version of the Minnesota multi-factor personal questionnaire (MMPQ), «Lifestyle index «, the variants of coping behavior was investigated using the methodology of E. Heim.Results. Moderate level of reactive and high level of personal anxiety was revealed in patients with post-exposure period. The MMPQ profile throughout the study period is characterized by a neurotic slope. Patients with VD in the post-exposure period more often use relatively adaptive forms of cognitive strategies, the constructiveness of which depends on the significance and severity of the overcoming situation. Among the options for emotional coping is dominated by adaptive forms. A wide range of behavioral strategies, both constructive and non — constructive, was revealed in patients with post-exposure period; there is a relatively narrow range of intense mechanisms of psychological protection, which are represented by their protective forms — «denial», «displacement», «intellectualization» and «reactive formations».Conclusions: The studies show the persistence in the post-exposure period, previously identified in patients with VD of psychological problems that fi t into the framework developed the theory of sensory conflict of Siberian Institute of Medical and Ecological Research, when developing long-term adaptive and non-adaptive reaction is complete the formation of the maladaptive psychological states. In the system of prevention of occupational pathology from the effects of vibration, it is necessary to provide measures of psycho-hygienic and psycho- prevention orientation for psychological adaptation of patients.

scholarly journals Assessment of the insecticidal activity of oral afoxolaner against Phlebotomus perniciosus in dogs

Parasite ◽  
2019 ◽  
Vol 26 ◽  
pp. 63
Author(s):  
Nadège Perier ◽  
Wilfried Lebon ◽  
Leon Meyer ◽  
Noua Lekouch ◽  
Nesrine Aouiche ◽  
...  
Keyword(s):  
Untreated Control ◽  
Exposure Period ◽  
Blood Feeding ◽  
Treated Group ◽  
Control Group ◽  
Untreated Control Group ◽  
Phlebotomus Perniciosus ◽  
Post Exposure ◽  
Insecticidal Efficacy ◽  
Healthy Dogs

Twelve healthy dogs were included in this laboratory efficacy study. Six dogs were randomly allocated based on body weight to an untreated control group and six to an afoxolaner (NexGard®) treated group. In the treatment group, afoxolaner was administered orally on Day 0 in accordance with label instructions. On Days 1, 14 and 28, each dog was exposed to 60 unfed female and 10 male Phlebotomus perniciosus sandflies for 1 h. At the end of each exposure period, sandflies were counted and assessed for viability and feeding status. There was no statistical difference in mortality (0.0–5.4%), nor in feeding proportion (61.6–78%) between the control and the treated groups at all 1-h post-exposure assessments. After collection, live fed and unfed sandflies were kept for viability assessments at 48 and 72 h post-exposure. In the untreated control group, the average percentages of live, fed, female sandflies after exposure, on Days 1, 14 and 28, ranged from 51% to 74% at 48 h and from 46% to 57% at 72 h, demonstrating model robustness over the 28 days of the study. Significantly fewer live fed sandflies were recorded for the afoxolaner treated group (p < 0.01). The insecticidal efficacy was 100%, 95.9% and 75.2% at 48 h post Days 1, 14 and 28 exposures, respectively, and 100%, 100% and 86.3% at 72 h post Days 1, 14, and 28 exposures, respectively. A single administration of oral afoxolaner (NexGard®) to dogs significantly killed P. perniciosus sandflies 48 and 72 h after blood feeding for 1 month.

scholarly journals DETERMINATION OF THE FUNCTIONAL STATE OF THE PERIPHERAL NERVOUS SYSTEM IN PATIENTS WITH VIBRATION DISEASE BY ELECTRONEUROMIOGRAPHY INDICES

2019 ◽  
Vol 98 (10) ◽  
pp. 1119-1123
Author(s):  
D. V. Rusanova ◽  
Larisa S. Vasileva ◽  
N. V. Slivnitsyna ◽  
O. L. Lakhman
Keyword(s):  
Functional State ◽  
Lower Extremities ◽  
The State ◽  
The Body ◽  
Local Vibration ◽  
Spinal Cord Neurons ◽  
Vibration Disease ◽  
Prolonged Contact ◽  
Upper And Lower Extremities ◽  
F Wave

Introduction. Vibration disease (VD) is a chronic occupational disease caused by the long-term influence of industrial vibration on the body, with prolonged contact with which a polyneuropathic syndrome is formed. Material and methods. 150 males were examined in the clinic. The first group consisted of 50 patients with VD associated with combined exposure to local and General vibration (48.7±3.1 years); the second - 50 patients with VB associated with exposure to local vibration (48.9±2.8 years); the third - 50 relatively healthy individuals without contact with vibration (49.1±2.5 years). Stimulation electroneuromyography (ENMG) was carried out according to the generally accepted method. The results of ENMG show demyelinating lesions of motor and sensory components to be registered in the examined VD patients, changes in the speed indices of axons of nerves of the upper and lower extremities are observed. Analysis of F-wave indices revealed the lesion of both the fastest and the slowest conductive fibers of the tibial and peroneal nerves in patients of both groups. There is an increase in the maximum amplitude of the F-wave and the F/M ratio, more pronounced in patients of the first examined group. In patients of the first and second examined groups, there is an increase in the blocks of the pulse, more pronounced with the combined effect of general and local vibration. Conclusion. Changes in the state of the peripheral nerves of the upper extremities are similar in patients of the first and second groups and consist in the presence of processes of demyelination of motor and sensory axons. In patients of the first group, there are more pronounced disorders in the state of the motor component of the nerves of the upper and lower extremities, while in persons of the second group there are sub-threshold changes in the lower extremities. Changes at the level of roots and in the functional state of the spinal cord neurons are more pronounced in patients of the second group.

Formation of pathology of internal organs in miners with vibration disease

2020 ◽  
pp. 399-403
Author(s):  
O. Yu. Korotenko ◽  
N. I. Panev ◽  
Yu. S. Korchagina ◽  
R. N. Panev ◽  
I. P. Danilov
Keyword(s):  
Cardiovascular System ◽  
Kidney Diseases ◽  
Coal Industry ◽  
Control Group ◽  
Internal Organs ◽  
Local Vibration ◽  
Vibration Disease ◽  
Long Time ◽  
Somatic Diseases ◽  
Medical Examinations

Introduction. Adverse working conditions can contribute to the development of not only occupational pathology, but also diseases with complex multifactorial etiology, such as hypertension, coronary heart disease, disorders of the musculoskeletal system, chronic non-specifi c respiratory diseases, as well as the formation of combined pathology, which worsens the course of these diseases and leads to the development of complications.The aim of the study is to study the manifestations of somatic pathology in coal industry workers with vibration disease.Materials and methods. We examined 144 coal mine workers with vibration disease caused by local vibration, and 161 control group miners who have been working in contact with local vibration for a long time (15 years or more) and do not have professional pathology.It was found that employees of coal mines with vibration disease more often (70,8%) than workers of the control group (27,3%) (p<0,001), there is a pathology of internal organs: diseases of the cardiovascular system (mainly arterial hypertension), diseases of the digestive system (functional disorders of the biliary tract and non-alcoholic fatt y liver disease), kidney diseases (mainly chronic pyelonephritis), as well as a combination of these diseases. With a more severe course of vibration disease (II degree), pathology of internal organs is more common (81.2%) than in patients with vibration disease of I degree (46.5%) (p<0.001). Conclusions. In miners with vibration disease, more oft en than in the control group, there is a pathology of internal organs: the cardiovascular system, digestive organs, kidneys, as well as a combination of several somatic diseases. In individuals with grade II vibration disease, internal organ pathology is more common than in patients with grade I vibration disease. Th e results obtained should be considered when developing treatment and rehabilitation measures for medical examinations and conducting preventive medical examinations of coal industry workers. 

Postural disorders in patients with vibration disease

2019 ◽  
pp. 314-318
Author(s):  
Larisa S. Vasileva ◽  
Natalya V. Slivnitsyna ◽  
Oleg L. Lakhman
Keyword(s):  
Center Of Pressure ◽  
Statistical Significance ◽  
Statistical Processing ◽  
Control Group ◽  
Combined Effects ◽  
Local Vibration ◽  
Vibration Disease ◽  
Eyes Closed ◽  
Significant Difference ◽  
Postural Disorders

Introduction. Vibration disease (VD) is one of the leading occupational diseases. One of the manifestations of this disease when exposed to general vibration may be a violation of balance.The aim of the study is to identify the imbalance and the causes of their occurrence in patients with vibration disease.Materials and methods. 3 groups of patients were examined. The first group consisted of 50 patients diagnosed with VD associated with combined exposure to local and general vibration (age 48.7±3.1 years); the second group consisted of 50 patients diagnosed with VD associated with exposure to local vibration (age 48.9+2.8 years); the control group consisted of 50 relatively healthy men not in contact with vibration (age 49.1+2.5 years). Survey on electronic stabilometer ST–150 (Biomera, Russia). Patients performed the Romberg test standing barefoot vertically on a stabilometric platform with a “European” stop position. Statistical processing of the results was carried out using the software package “Statistica 10.0” (StatSof, USA, 2011). Methods of descriptive statistics included estimation of median, lower and upper quartiles. The statistical significance of the differences was determined using the nonparametric Wilkinson method. Differences were considered statistically significant at p<0.05.Results. In the analysis of the obtained stabilometric parameters found that in the first group of patients marked imbalance.Moreover, in comparison with the second group and the control group in the phase with eyes closed, patients are more difficult to maintain a given posture, which increases the length of statokinesigram (p=0.02 and p=0.005), increasing the speed of movement of the center of pressure (p=0.03 and p=0.004) and the square of the deviation of the center of pressure (p=0.03 and p=0.004). When closing the eyes, patients put more effort to maintain balance, which affects the rate of mechanical work (p=0.001 and p=0.001). When comparing the second group with the control group, no statistically significant difference was found in the main stabilometric indicators.Conclusions: In the group of patients with VD associated with the combined effects of local and general vibration, marked (64%) and moderate (36%) postural disorders, especially in the phase of closed eyes. In the group of patients with VS associated with local vibration exposure and in the control group, imbalance was detected in 10% and 6%, respectively. The leading role in the occurrence of postural disorders in patients with VD, associated with the combined effects of local and general vibration, plays the formation of a focus of stagnant excitation in the centers of vibration sensitivity. In the future, the pulse can spread to nearby centers of pain, temperature sensitivity and proprioception, which contributes to the emergence of lower limb polyneuropathy and impaired stability in patients with vibration disease.

Vibration disease: erectile dysfunction as a comorbidity problem

2020 ◽  
pp. 36-43
Author(s):  
S. Babanov ◽  
N. Tatarovskay
Keyword(s):  
Erectile Dysfunction ◽  
Questionnaire Survey ◽  
Erectile Function ◽  
Control Group ◽  
Local Vibration ◽  
Vibration Disease ◽  
Male Patients ◽  
And Control ◽  
The Impact ◽  
Second Degree

The article presents data (based on a questionnaire survey) on the impact of vibration disease from the action of local and General vibration on the erectile function of men. The main changes in the parameters of erectile function (frequency, need, etc.) are described in the case of first and second-degree vibrational disease caused by local vibration, and in the case of first-and second-degree vibrational disease caused by General vibration based on data from a questionnaire survey of male patients and control group.

CHRYSOTILE-RELATED ASBESTOSIS IN THE POST-EXPOSURE PERIOD. STUDY DESIGN AND PRELIMINARY RESULTS

2021 ◽  
Author(s):  
S.V. Kashanskiy ◽  
◽  
E.K. Kovalevskiy ◽  
N.O. Milovankina ◽  
Keyword(s):  
Working Conditions ◽  
Exposure Period ◽  
Cumulative Exposure ◽  
Dust Exposure ◽  
Control Group ◽  
Industrial Workers ◽  
Retrospective Case ◽  
Post Exposure ◽  
Asbestos Fibers ◽  
Set Up

Abstract: Abstract. A retrospective case-control study among former workers of PJSC Uralasbest has been launched to establish the main clinical features of the disease as well as causes and structure of mortality in patients with chrysotile-related asbestosis in the post-exposure period taking into cumulative dust exposure. First, we collected information about 850 asbestosis cases diagnosed in the Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers in 1946-2000. Control group of workers without asbestosis, matched by sex, duration of work, working conditions, cumulative dust exposure, social and living conditions, was set up as a control group. All primary information was entered in a specially developed database. Second, we established the vital status of the cases and the controls as of January 1, 2020. A considerable improvement of working conditions for the main jobs at PJSC Uralasbest in the second half of the 20th century leading to a statistically significant decrease in the cumulative exposure both by total dust and respirable chrysotile asbestos fibers. Improved working conditions have influenced increasing the duration of work until the development of the disease as shown by the rise in the proportion of workers with diagnosed asbestosis, mainly stage I, workers with 20 or more years after the first exposure.

scholarly journals MALE REPRODUCTIVE FUNCTION IN CONCURRENT VIBRATION DISEASE AND ARTERIAL HYPERTENSION

2019 ◽  
Vol 4 (1) ◽  
pp. 32-36
Author(s):  
Sergey A. Babanov ◽  
Rimma A. Baraeva
Keyword(s):  
Erectile Dysfunction ◽  
Arterial Hypertension ◽  
Erectile Function ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Control Group ◽  
Androgen Deficiency ◽  
Local Vibration ◽  
Body Vibration ◽  
Vibration Disease

Objectives - to study the severity of androgen deficiency and erectile dysfunction in patients with vibration disease and in its combination with arterial hypertension. Material and methods. 145 male patients with various forms of vibration disease were thoroughly examined. The following groups were defined - I stage and II stage vibration disease induced by local vibration; II stage, induced by local vibration with concurrent arterial hypertension; I and II stage vibration disease induced by whole body vibration; II stage vibration disease induced by whole body vibration with concurrent arterial hypertension. The control group included 30 patients. Evaluation of erectile function in men with vibration disease and its combination with arterial hypertension was carried out using the scale of severity of erectile dysfunction (International Index of Erectile Function, IIEF-5). The questionnaire for detection of androgen deficiency (Dedov II, Kalinchenko SYu, 2006) and the AMS (aging males' symptoms) questionnaire assisted in revealing the symptoms of aging in men. Results. According to the IIEF-5 questionnaire results the erectile dysfunction was defined in patients with vibration disease, most pronounced in II stage of vibration disease induced by whole body vibration and in vibration disease of any etiology with concurrent arterial hypertension. AMS-questionnaire presented the most expressed signs of androgen deficiency in patients with II stage of vibration disease induced by whole body vibration and in vibration disease of any etiology with concurrent arterial hypertension (p

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