Formation of pathology of internal organs in miners with vibration disease

Author(s):  
O. Yu. Korotenko ◽  
N. I. Panev ◽  
Yu. S. Korchagina ◽  
R. N. Panev ◽  
I. P. Danilov

Introduction. Adverse working conditions can contribute to the development of not only occupational pathology, but also diseases with complex multifactorial etiology, such as hypertension, coronary heart disease, disorders of the musculoskeletal system, chronic non-specifi c respiratory diseases, as well as the formation of combined pathology, which worsens the course of these diseases and leads to the development of complications.The aim of the study is to study the manifestations of somatic pathology in coal industry workers with vibration disease.Materials and methods. We examined 144 coal mine workers with vibration disease caused by local vibration, and 161 control group miners who have been working in contact with local vibration for a long time (15 years or more) and do not have professional pathology.It was found that employees of coal mines with vibration disease more often (70,8%) than workers of the control group (27,3%) (p<0,001), there is a pathology of internal organs: diseases of the cardiovascular system (mainly arterial hypertension), diseases of the digestive system (functional disorders of the biliary tract and non-alcoholic fatt y liver disease), kidney diseases (mainly chronic pyelonephritis), as well as a combination of these diseases. With a more severe course of vibration disease (II degree), pathology of internal organs is more common (81.2%) than in patients with vibration disease of I degree (46.5%) (p<0.001). Conclusions. In miners with vibration disease, more oft en than in the control group, there is a pathology of internal organs: the cardiovascular system, digestive organs, kidneys, as well as a combination of several somatic diseases. In individuals with grade II vibration disease, internal organ pathology is more common than in patients with grade I vibration disease. Th e results obtained should be considered when developing treatment and rehabilitation measures for medical examinations and conducting preventive medical examinations of coal industry workers. 

Author(s):  
S. N. Filimonov ◽  
N. I. Panev ◽  
O. Yu. Korotenko ◽  
N. A. Evseeva ◽  
I. P. Danilov ◽  
...  

Introduction. Th e high level of professional and production-related pathology among workers of the coal industry, as well as the frequent development of their combined pathology with an unfavorable prognosis determine the relevance of studying the prevalence of somatic pathology in miners with occupational diseases of the respiratory system.The aim of the study was to explore the prevalence of internal organs pathology in coal industry workers with occupational lung diseases (anthracosilicosis, chronic dust bronchitis, chronic obstructive pulmonary disease).Materials and methods. 788 store miners and shaft  sinkers with previously diagnosed occupational respiratory diseases (anthracosilicosis, chronic dust bronchitis, chronic obstructive pulmonary disease) and 161 miners, working for a long time in harmful labour conditions and having no occupational pathology (the control group) were examined.Results. It was revealed that the workers of the coal industry with occupational diseases of the respiratory system pathology of internal organs occurs more often than the workers of the control group, including: diseases of the cardiovascular system (hypertension, angina pectoris I and II functional classes), diseases of the digestive system (nonalcoholic fatty liver disease and chronic pancreatitis), kidney disease (chronic pyelonephritis), as well as a combination of several somatic diseases.Conclusions. In miners with occupational diseases of the respiratory system more oft en than in the control group, there is a pathology of the internal organs: diseases of the cardiovascular system, digestive organs, kidneys, as well as a combination of several somatic diseases. Th e data obtained should be considered during periodic medical examinations and medical examinations for the development of timely therapeutic and preventive and rehabilitation measures. 


Author(s):  
E.E. Konnikova ◽  
◽  
A.G. Popova ◽  
N.I. Slugrov ◽  

Abstract: A statistical analysis of stabilometric study results of 50 male patients with vibration disease (VD) from the effects of general vibration (GV) (average work experience 26,7±6,2) has been carried out. The control group (CG) included 50 men who have not been exposed to the general vibration. The compared groups were comparable by age: the average age of patients with vibration disease was 56.34+5.15, patients of the control group-58.22+-7.05. The study of the support symmetry and equilibrium function was carried out using the Romberg test on the St-150 stabiloplatform (Biomera, Moscow) in a vertical stand with European installation of feet in the positions of open (OE) and closed eyes (CE). A comparative analysis of the parameters of support symmetry in patients with VD from GV revealed a statistically significant sagittal asymmetry in the phases of OE and CE than in individuals of CG. Among the balancing parameters, the most informative parameters of computer stabilometry in patients with VD from GV were: an increase in the area of the statokinesiogram, a decrease in energy efficiency in both phases of the study, and an increase in the speed of the statokinesiogram in phase with CE. Computer stabilometry can be recommended as an additional objective research method in the diagnosis of early stages of VD from GV to improve the quality of periodic medical examinations.


Author(s):  
Larisa S. Vasileva ◽  
Natalya V. Slivnitsyna ◽  
Oleg L. Lakhman

Introduction. Vibration disease (VD) is one of the leading occupational diseases. One of the manifestations of this disease when exposed to general vibration may be a violation of balance.The aim of the study is to identify the imbalance and the causes of their occurrence in patients with vibration disease.Materials and methods. 3 groups of patients were examined. The first group consisted of 50 patients diagnosed with VD associated with combined exposure to local and general vibration (age 48.7±3.1 years); the second group consisted of 50 patients diagnosed with VD associated with exposure to local vibration (age 48.9+2.8 years); the control group consisted of 50 relatively healthy men not in contact with vibration (age 49.1+2.5 years). Survey on electronic stabilometer ST–150 (Biomera, Russia). Patients performed the Romberg test standing barefoot vertically on a stabilometric platform with a “European” stop position. Statistical processing of the results was carried out using the software package “Statistica 10.0” (StatSof, USA, 2011). Methods of descriptive statistics included estimation of median, lower and upper quartiles. The statistical significance of the differences was determined using the nonparametric Wilkinson method. Differences were considered statistically significant at p<0.05.Results. In the analysis of the obtained stabilometric parameters found that in the first group of patients marked imbalance.Moreover, in comparison with the second group and the control group in the phase with eyes closed, patients are more difficult to maintain a given posture, which increases the length of statokinesigram (p=0.02 and p=0.005), increasing the speed of movement of the center of pressure (p=0.03 and p=0.004) and the square of the deviation of the center of pressure (p=0.03 and p=0.004). When closing the eyes, patients put more effort to maintain balance, which affects the rate of mechanical work (p=0.001 and p=0.001). When comparing the second group with the control group, no statistically significant difference was found in the main stabilometric indicators.Conclusions: In the group of patients with VD associated with the combined effects of local and general vibration, marked (64%) and moderate (36%) postural disorders, especially in the phase of closed eyes. In the group of patients with VS associated with local vibration exposure and in the control group, imbalance was detected in 10% and 6%, respectively. The leading role in the occurrence of postural disorders in patients with VD, associated with the combined effects of local and general vibration, plays the formation of a focus of stagnant excitation in the centers of vibration sensitivity. In the future, the pulse can spread to nearby centers of pain, temperature sensitivity and proprioception, which contributes to the emergence of lower limb polyneuropathy and impaired stability in patients with vibration disease.


Author(s):  
S. Babanov ◽  
N. Tatarovskay

The article presents data (based on a questionnaire survey) on the impact of vibration disease from the action of local and General vibration on the erectile function of men. The main changes in the parameters of erectile function (frequency, need, etc.) are described in the case of first and second-degree vibrational disease caused by local vibration, and in the case of first-and second-degree vibrational disease caused by General vibration based on data from a questionnaire survey of male patients and control group.


Author(s):  
Лахман ◽  
Oleg Lakhman ◽  
Катаманова ◽  
Elena Katamanova ◽  
Кулешова ◽  
...  

The article presents the results of the studies of the central and peripheral nervous systems, psychoemotional status of patients with vibration disease associated with exposure to the local vibration in the post-exposure period. The stud-ies were performed in patients with vibration disease (n=18) who do not work in the contact with the local vibration at present. The mean age of the patients was 50.7±5.4years, the mean length of service in the contact with local vibration –17.9±2.8years, the mean post-exposure period – 5.2±2.2years. 30male persons having no contact with industrial hazard were comprised the control group. Electroencephalography, electroneuromyography, recording of somatosensory evoked potentials were carried out and patients’ personality peculiarities were studied. The changes of the brain bioelectrical activity, disorders of the autonomic and afferent regulation of the cerebral level, dysfunc-tion in diencephalic structures, disorders of the subcortical and cortical structures of the central afferent pathways; demyelization of the peripheral nerves of the upper and lower extremities were set in patients with vibration disease in the post-exposure period. Psychological studies have shown that patients with vibration disease in the post-exposure period preserve such psychological peculiarities as neuroticism manifested with inner tension, nervousness and chronic feeling of discomfort; depressive tendencies being a sign of the existing distress, and anxious-hypochondriac features in the structure of personality traits. All of the above result in formation of stable uncompensated clinical conditions observed in patients with vibration disease caused by local vibration exposure, even after the termination of harmful production factors.


2019 ◽  
Vol 21 (94) ◽  
pp. 136-141
Author(s):  
V. P. Martynyshyn

The investigation of the skin toxicity of the liniment “VetMikoDerm” for prolonged use was performed on young and healthy laboratory rats with intact skin, body weight 200–220 g. The investigated environment was applied to a clean, non-woolly area (dorsal/lateral surface) of at least 10% of the total surface area. The spotted thistle oil was applied to the pre-prepared area of the skin of the animals of the control group, and the other two experimental groups of animals got the studied drug at the doses of 50 (I) and 500 mg/kg (II), respectively. The drug was applied to the skin daily for 28 days. At the end of the experiment, after the decapitation of the rats conducted under the light etheric anesthesia, a complete pathoanatomical dissection was performed, the coefficients of the mass of the internal organs were determined, samples of liver, kidney and skin tissues were taken for their histological examination. According to the results it was established that the liver and kidneys histology, and skin of rats of the 1st experimental group were similar to those that were of the control animals. At the same time, receiving the maximum dose (10 times the therapeutic dose) of the drug “VetMikoDerm”, the majority of rats of the 2nd group showed a discomplication of the lamellar structure of the liver lobules, hepatocytes were placed in separate groups, sinusoidal capillaries were expanded. The presence of hepatocytes with heterogeneous, granular and weakly colored cytoplasm was observed in the central parts of the lobules, the nuclei of individual hepatocytes were increased, indicating the development of granular protein degeneration of the parenchyma. Histologically, under these conditions, foci of granular dystrophy of the epithelium of the vorticular and direct renal tubules with the expansion of their lumen were found in the structure of kidney of rats. The kernels of individual nephropyelitis had signs of karyopicnosis and cariorexis. The histological structure of skin of rats in all experimental groups was of the same type and consisted of the epidermis, dermis and hypodermis. Animals of the 2nd experimental group which repeatedly and for a long time were applied a “VetMikoDerm” lineulation in a dose that exceeded its optimal amount by 10 times showed the epidermal thickening, the presence of small-mesenchymal polymorphocytic infiltration, microcirculatory corneal disorder and sebaceous gland hyperplasia  glands in the dermis that indicated the development of a compensatory-adaptive reaction in places of application of a 10-fold dose of the investigational medicinal product.


2019 ◽  
Vol 4 (1) ◽  
pp. 32-36
Author(s):  
Sergey A. Babanov ◽  
Rimma A. Baraeva

Objectives - to study the severity of androgen deficiency and erectile dysfunction in patients with vibration disease and in its combination with arterial hypertension. Material and methods. 145 male patients with various forms of vibration disease were thoroughly examined. The following groups were defined - I stage and II stage vibration disease induced by local vibration; II stage, induced by local vibration with concurrent arterial hypertension; I and II stage vibration disease induced by whole body vibration; II stage vibration disease induced by whole body vibration with concurrent arterial hypertension. The control group included 30 patients. Evaluation of erectile function in men with vibration disease and its combination with arterial hypertension was carried out using the scale of severity of erectile dysfunction (International Index of Erectile Function, IIEF-5). The questionnaire for detection of androgen deficiency (Dedov II, Kalinchenko SYu, 2006) and the AMS (aging males' symptoms) questionnaire assisted in revealing the symptoms of aging in men. Results. According to the IIEF-5 questionnaire results the erectile dysfunction was defined in patients with vibration disease, most pronounced in II stage of vibration disease induced by whole body vibration and in vibration disease of any etiology with concurrent arterial hypertension. AMS-questionnaire presented the most expressed signs of androgen deficiency in patients with II stage of vibration disease induced by whole body vibration and in vibration disease of any etiology with concurrent arterial hypertension (p


Author(s):  
Igor V. Bukhtiyarov ◽  
Alaksandr G. Chebotarev ◽  
Nikolay N. Courierov ◽  
Oleg V. Sokur

Working conditions of employees of mining enterprises are characterized by class 3 (harmful) 2–4 degrees, which determine the level of occupational disease. T e highest rate of occupational morbidity (111.2 cases per 10 thousand workers who have undergone periodic medical examinations) occurs in mine workers, and it is signif cantly higher than in quarry workers. In underground workers in the structure of occupational disease, the f rst place is occupied by diseases of the bronchopulmonary system (30.1%), in quarry workers — vibration disease (48.3%). T ese enterprises have shown an increasing trend in recent years of deaths in the workplace, mainly from diseases of the cardiovascular system.


2019 ◽  
Vol 98 (10) ◽  
pp. 1102-1107
Author(s):  
Liudmila B. Masnavieva ◽  
I. V. Kudaeva ◽  
Y. A. Kuznetsova ◽  
O. V. Naumova

Introduction. Vibration disease occupies one of the leading places in the structure of occupational pathology and is caused by exposure to both local and general vibration. Since the mechanism of local and general vibration effects on the body differs, it can be assumed that their effect on the cardiovascular system will have distinctive features. The aim of the work was to study the content of specific autoantibodies, which characterize the state of the cardiovascular system, in patients with vibration disease caused by exposure to local and combined vibration. Material and methods. The relative levels of specific autoantibodies to antigens, reflecting the state of the heart and the vascular bed, were determined in the blood of persons with vibration disease caused by exposure to local and combined vibration (29 and 36 cases, respectively). Results. 18 to 26% of persons with the vibratory disease caused by the effect of combined vibration were found to have elevated levels of autoantibodies to components of the membrane and cytoplasm of myocardial cells, components of the cytoplasm of neutrophils and endothelial cells, β1-adrenoreceptors, PAPP-A, and cardiomyosin protein. In the group of individuals exposed to local vibration, the frequency of occurrence of elevated levels of antibodies by more than 20% was detected only for β1-adrenoreceptors and PAPP-A protein. Elevated levels of other indices were observed in 10-14% of individuals in this group. The levels of antibodies to components of the membrane of myocardial cells and platelets were higher in patients with the vibratory disease caused by exposure to a combined vibration than in individuals with vibratory syndrome caused by the action of local vibration. conclusion. Elevated levels of auto-AT to platelet membrane structures may be due to changes in their membranes caused by the accumulation of highly toxic lipid peroxidation metabolites.


2020 ◽  
Vol 99 (7) ◽  
pp. 699-703
Author(s):  
Anastasia V. Yamshchikova ◽  
Arnold N. Fleishman ◽  
Margarita O. Gidayatova ◽  
Alla A. Kungurova

Introduction. The relevance of the study is dictated by the difficulties of differential diagnosis of neural lesions of the upper extremities in vibration disease induced by local vibration. The most frequent involvement of the distal nerves of the upper extremities can be due to both a polyneuropathic diffuse disturbance without compression and a compression tunnel lesion. Taken into account the different approaches to the treatment of these conditions, there is a need to study the features of distal nerve damage in the case of vibration damage.Aim of the study was to investigate the macrostructural and functional features of distal lesions of the peripheral nerves of the upper extremities in vibration disease patients.Material and methods. 57 men aged 40-60 years were examined at the clinic of the Research Institute for Complex Problems of Hygiene and Occupational Diseases in Novokuznetsk, 30 patients with a proven diagnosis of vibration disease were included in the main group, 27 cases who had never worked in contact with industrial vibration were included in the control group. An electroneuromyographic and ultrasound study of the median and ulnar nerve were performed in all cases.Results. A significant increase in the distal latency of the median nerves and a decrease in the speed of sensory conduction along the nerves of the upper extremities in the main group were revealed. According to the ultrasound examination of the nerves, there was no statistical difference in the nerve cross-sectional area at the level of the wrist in the main and control groups. The frequency of compression lesions of the median nerve in the carpal canal in the main group accounted for 16%.Conclusions. With prolonged exposure to local vibration, a distal polyneuropathic diffuse lesion of the nerves of the upper extremities often develops. A combination of vibration disease due to local vibration and carpal tunnel syndrome occurs in 16% of cases.


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