scholarly journals Pulmonary embolism as a complication of fracture of the proximal end of the humerus - literature review

2021 ◽  
Vol 11 (9) ◽  
pp. 388-395
Author(s):  
Wojciech Wokurka ◽  
Agata Węgrzyniak ◽  
Iga Dudek ◽  
Piotr Piech

Introduction and purpose: Pulmonary embolism (PE) is one of the leading causes of death worldwide. There are many factors that increase the risk of its occurence. High costs of treatment, non-specific symptoms and high mortality of the disease determine the further search for new methods of treatment and diagnostics. The aim of the study is to determine the incidence of PE in patients after fracture of the proximal end of the humerus. Materials and methods: A literature search was conducted in the PubMed MEDLINE database of medical publications using the following keywords: pulmonary embolism, deep vein thrombosis, proximal humerus fracture. Results: Among the found articles, 4 original papers describing the problems of pulmonary embolism after fractures of the proximal end of the humerus were qualified for further analysis. The incidence of PE after this type of fracture is rare and ranges from 1.3% to 5.1%. Moreover, PE was not the cause of death of any patient in the analyzed literature. Conclusion: The need for further randomized controlled trials on a large group of patients operated with the same technique was demonstrated, including subgroups with and without antithrombotic chemoprophylaxis.

2016 ◽  
Vol 01 (04) ◽  
pp. 032-035
Author(s):  
Seetharam Vankudoth ◽  
Madhurima banoth

AbstractVenous thromboembolism, causing Pulmonary Embolism (PE), is one of the major cardiovascular causes of death. We are reporting three cases of pulmonary thromboembolism without deep vein thrombosis and with normal levels of homocysteine, protein C and S, anti-thrombin III levels. All three cases managed with thrombolysis with streptokinase, out of three cases two cases systemic thrombolysis given and one case catheter guided thrombolysis given and discharged on oral anticoagulant with target range of PT with INR 2-3.on subsequent follow-up one case was diagnosed lymphoma and he was treated successfully in our institution.


2016 ◽  
Vol 32 (9) ◽  
pp. 620-627 ◽  
Author(s):  
Jun Jiang ◽  
Yuanyong Jiao ◽  
Xiwei Zhang

Objectives To perform a meta-analysis of randomized controlled trials assessing the effectiveness of inferior vena cava filters in patients with deep vein thrombosis for preventing pulmonary embolism. Method Relevant randomized controlled trials of inferior vena cava filters for the prevention of pulmonary embolism were identified by searching electronic databases updated in February 2016. Relative risks of recurrent pulmonary embolism, recurrent deep vein thrombosis, and mortality at three months were analyzed. Results Three published randomized controlled trials were included involving a total of 863 deep vein thrombosis patients. No significant differences were detected with inferior vena cava filters placement with regard to the incidence of recurrent pulmonary embolism or fatal pulmonary embolism. There were also no significant differences in the incidence of recurrent deep vein thrombosis or mortality with inferior vena cava filters placement at three months. Conclusions Inferior vena cava filter in addition to anticoagulation was not associated with a reduction in the incidence of recurrent pulmonary embolism as compared with anticoagulation alone in patients with deep vein thrombosis in the short term.


The Lancet ◽  
2006 ◽  
Vol 367 (9516) ◽  
pp. 1075-1079 ◽  
Author(s):  
Liam Smeeth ◽  
Claire Cook ◽  
Sara Thomas ◽  
Andrew J Hall ◽  
Richard Hubbard ◽  
...  

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