scholarly journals Noninvasive Determine Lead Poisoning Biomarker for Human Body—Design and Manufacture on Innovated New-XRF Analyzer of Bone Lead

Author(s):  
Xianfeng Wang ◽  
Haiying Wang ◽  
Yijun Gao ◽  
Jun Lu ◽  
Dejia Hou
2012 ◽  
pp. 230-234 ◽  
Author(s):  
Juan Bernardo Gerstner Garcés

With the increase of violence and use of firearms in Colombia, we may see more cases of lead poisoning in our environment, and must be prepared to diagnose and treat them. Subtle signs and symptoms as unexplained anemia, gastro-intestinal discomfort and abdominal cramps, and severe as changes in behavior and neurological status, nephropathy, and unexplained death, may be associated with a history of gunshot wounds and projectiles in the human body, and must offer the patient knowledge and management strategies of pathology.


Safety ◽  
2018 ◽  
Vol 4 (4) ◽  
pp. 60
Author(s):  
Cody Morris ◽  
Harish Chander

Purpose: The objective of this review was to analyze the physiological impact of fire suppression on the human body. Design: The literature review included studies focused on workload requirements for common firefighting tasks, effect of health status on the firefighting profession, and attempts to establish a minimum physiological workload capacity for successful performance of firefighting. Findings: The existing literature provides evidence of the high degree of physiological stress that firefighters are under during fire suppression tasks and the great degree of maximal physical capacity that firefighting often requires. Firefighters often operate close to maximal aerobic capacity while performing tasks common to the profession. This is especially true due to the added physiological stress placed on the human body while wearing personal protective equipment during firefighting. Conclusions: Future investigations are necessary to further explore markers of physiological stress during firefighting and the impact that it may have on the ability to withstand the development of disease as well as fire suppression safety. Using completion time of fire suppression tasks as a criterion of success may be an important consideration in addition to the physiological requirements of the occupation when assessing the appropriateness of an individual to be a firefighter. An important future consideration is the effect that fire suppression activities may have on reaction time in critical situations in which life-and-death decisions must be made.


2013 ◽  
Vol 364 ◽  
pp. 14-18
Author(s):  
Xuan Zuo Liu ◽  
Hui Min Wang ◽  
Fei Zhang ◽  
Yu Long Zhang ◽  
Qian Cheng Liu

This paper designs the three-dimensional body modelling of a solar car prototype mainly according to the World Solar Challenge rules, and carries on the flow field digital simulation analysis. This paper analyzes the air resistance of the car body and adjusts to the body shape, and ultimately gets a model well accorded with air dynamics. This paper provides scientific theoretical basis for the design and manufacture of the solar car prototype.


2017 ◽  
Vol 8 (2) ◽  
pp. 27
Author(s):  
Agung Prakoso

The existence o f fe e t as the part of the human body is very important to support the daily activities which is to support the body and to walk. The lost of the under knee part (amputation) is the dominant case of the total cases of amputation in Indonesia. So that we need a tool to restore the balance of the human body to be able to do our daily activity. The tool is called prostheses. The design and manufacture of prototypeshank prostheses under knee is intended for persons who have 162 cm height and 57 Kg of average weight. Prostheses are aimed to the persons who only lost one limb below the knee. In this design, the length of the shank can be set according to the length of leg amputated and is intended to persons who are still experiencing high growth (teenager). The material is stainless steel 316L. The shank has a length 200-300 mm, width 67 mm and 2 mm thick.


PEDIATRICS ◽  
1993 ◽  
Vol 92 (2) ◽  
pp. 265-271
Author(s):  
Morri E. Markowitz ◽  
Polly E. Bijur ◽  
Holly Ruff ◽  
John F. Rosen

Background. For children with asymptomatic moderate lead poisoning (Blood lead level [BPb] 25 to 55 µg/dL [1.21 to 2.66 µmol/L]), treatment with the chelating agent calcium disodium versenate (CaNa2EDTA) is recommended for all those children with a BPb level >45 µg/dL (2.17 µmol/L) and for those with a BPb level of 25 to 44 µg/dL (1.21 to 2.13 µmol/L) who also have a positive lead mobilization test. However, controlled studies demonstrating its efficacy at inducing a sustained reduction in BPb level or lead-related toxicity have not been performed in children with moderate lead poisoning. This study assesses the relationship between CaNa2EDTA chelation and measures of lead burden and toxicity in children with moderate lead poisoning. Methods. Two hundred one children with moderate lead poisoning were enrolled. Sequential changes in BPb concentrations, bone lead level as measured by Lα-x-ray fluorescence, and lead-induced toxicity as assessed by erythrocyte protoporphyrin levels were determined over a 7-week period. From this group, children with a positive lead mobilization test received CaNa2EDTA chelation therapy. Results. Children with positive lead mobilization tests had on average higher initial BPb, bone lead, and erythrocyte protoporphyrin concentrations. The chelated children decreased approximately 4.7 µg/dL (0.23 µmol/L), 41 corrected net counts, and 24 µg/dL (0.46 µmol/L) more than the unchelated children on BPb, bone lead, and erythrocyte protoporphyrin values, respectively. However, children with higher initial levels decreased the most, whereas children with lower initial levels showed the least decline, with or without treatment. When the initial values on the measures were controlled analytically, or when subgroups matched on initial levels were compared, there were no significant differences between the chelated and unchelated children. Conclusions. The apparent effectiveness of CaNa2EDTA at reducing lead burden and toxicity is no longer observed when the pretreatment levels are considered. The findings suggest that sufficient doubt about CaNa2EDTA efficacy now exists to warrant a randomized controlled trial of chelation therapy in moderately lead-poisoned children. However, until such studies are performed, it would be premature to withhold chelation treatment on the basis of this study alone.


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