Associations between Short-Term Exposure to Particulate Matter and Ultrafine Particles with Lung Function in Schoolchildren from the German CorPuScula Study

ObjectiveExposure to particulate matter (PM) is a risk factor to diabetes, but the underlying mechanism is unclear. Adipokines play important roles in glucose metabolism. This study examined the associations between short-term exposure to ambient PM and adipokine levels and evaluated whether metabolic disorders could enhance susceptibility to PM-induced health effects.Research design and methodsIn a panel study (SCOPE, Study Comparing the Cardiometabolic and Respiratory Effects of Air Pollution Exposure on Healthy and Pre-diabetic Individuals) in Beijing, China, 60 pre-diabetic individuals and 60 healthy controls completed two to seven clinical visits. The associations between serum adiponectin, leptin, and resistin levels and the moving average (MA) mass concentration of PM2.5 and number concentrations of ultrafine particles (UFP) and accumulation-mode particles (AMP) during the 1–14 days prior to clinical visits, and the effects of metabolic disorders on any such associations, were evaluated using a linear mixed-effects model.ResultsShort-term exposure to ambient UFP and AMP was inversely associated with adipokine levels at 1–14 days prior to clinical visits. For example, each IQR increment in 1 day MA UFP exposure (6.0×103/cm3) was associated with −14.0% (95% CI −20.9%, −6.4%), −6.6% (95% CI −12.4%, −0.4%), and −8.5% (95% CI −14.5%, −2.2%) changes in adiponectin, leptin, and resistin levels, respectively. There was no significant association between adipokine levels and PM2.5 exposure. UFP and AMP exposure was associated with a greater decrease in adiponectin level and a weaker change in leptin level among participants with high insulin resistance levels. Glucose status did not modify PM-induced changes in adipokine levels.ConclusionHigh level of insulin resistance could aggravate the adverse metabolic impact of exposure to UFP and AMP.

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The exposure metric choices have significant impact on the association between short-term exposure to outdoor particulate matter and changes in lung function: Findings from a panel study in chronic obstructive pulmonary disease patients

The Science of The Total Environment ◽

10.1016/j.scitotenv.2015.10.114 ◽

2016 ◽

Vol 542 ◽

pp. 264-270 ◽

Cited By ~ 23

Author(s):

Yang Ni ◽

Shaowei Wu ◽

Wenjing Ji ◽

Yahong Chen ◽

Bin Zhao ◽

...

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Particulate Matter ◽

Lung Function ◽

Pulmonary Disease ◽

Panel Study ◽

Chronic Obstructive ◽

Short Term ◽

Obstructive Pulmonary Disease ◽

Short Term Exposure

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Associations between short-term exposure to particulate matter and ultrafine particles and myocardial infarction in Augsburg, Germany

International Journal of Hygiene and Environmental Health ◽

10.1016/j.ijheh.2015.05.002 ◽

2015 ◽

Vol 218 (6) ◽

pp. 535-542 ◽

Cited By ~ 25

Author(s):

Kathrin Wolf ◽

Alexandra Schneider ◽

Susanne Breitner ◽

Christa Meisinger ◽

Margit Heier ◽

...

Keyword(s):

Myocardial Infarction ◽

Particulate Matter ◽

Ultrafine Particles ◽

Short Term ◽

Short Term Exposure

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Seasonal Modification In The Effect Of Short-Term Exposure To Ambient Fine Particulate Matter On The Lung Function Of School Children In Dhaka, Bangladesh

ISEE Conference Abstracts ◽

10.1289/isee.2015.2015-1184 ◽

2015 ◽

Vol 2015 (1) ◽

pp. 1184

Author(s):

Saira Tasmin ◽

Chris Fook Sheng Ng ◽

Kayo Ueda ◽

Shinya Yasumoto ◽

Chiho Watanabe

Keyword(s):

Particulate Matter ◽

Lung Function ◽

School Children ◽

Fine Particulate Matter ◽

Short Term ◽

Fine Particulate ◽

Short Term Exposure

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Effects of Short-term Exposure to Ambient Particulate Matter on the Lung Function of School Children in Dhaka, Bangladesh

Epidemiology ◽

10.1097/ede.0000000000001012 ◽

2019 ◽

Vol 30 ◽

pp. S15-S23 ◽

Cited By ~ 1

Author(s):

Saira Tasmin ◽

Chris Fook Sheng Ng ◽

Andrew Stickley ◽

Nasiruddin Md ◽

Golam Saroar ◽

...

Keyword(s):

Particulate Matter ◽

Lung Function ◽

School Children ◽

Ambient Particulate Matter ◽

Short Term ◽

Short Term Exposure

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Non-accidental mortality risk of short-term exposure to fine particulate matter and its components in Tokyo

Environmental Epidemiology ◽

10.1097/01.ee9.0000608888.88110.fc ◽

2019 ◽

Vol 3 ◽

pp. 270-271

Author(s):

Michikawa T ◽

Takami A ◽

Yoshino A ◽

Sugata S ◽

Ueda K ◽

...

Keyword(s):

Particulate Matter ◽

Mortality Risk ◽

Fine Particulate Matter ◽

Short Term ◽

Fine Particulate ◽

Short Term Exposure

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Effect of Short-Term Exposure to Fine Particulate Matter and Temperature on Acute Myocardial Infarction in Korea

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18094822 ◽

2021 ◽

Vol 18 (9) ◽

pp. 4822

Author(s):

Jiyoung Shin ◽

Jongmin Oh ◽

In Sook Kang ◽

Eunhee Ha ◽

Wook Bum Pyun

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Particulate Matter ◽

Fine Particulate Matter ◽

Ambient Air ◽

Cold Season ◽

Short Term ◽

Fine Particulate ◽

Short Term Exposure ◽

The Impact

Background/Aim: Previous studies have suggested that the short-term ambient air pollution and temperature are associated with myocardial infarction. In this study, we aimed to conduct a time-series analysis to assess the impact of fine particulate matter (PM2.5) and temperature on acute myocardial infarction (AMI) among adults over 20 years of age in Korea by using the data from the Korean National Health Information Database (KNHID). Methods: The daily data of 192,567 AMI cases in Seoul were collected from the nationwide, population-based KNHID from 2005 to 2014. The monitoring data of ambient PM2.5 from the Seoul Research Institute of Public Health and Environment were also collected. A generalized additive model (GAM) that allowed for a quasi-Poisson distribution was used to analyze the effects of PM2.5 and temperature on the incidence of AMI. Results: The models with PM2.5 lag structures of lag 0 and 2-day averages of lag 0 and 1 (lag 01) showed significant associations with AMI (Relative risk [RR]: 1.011, CI: 1.003–1.020 for lag 0, RR: 1.010, CI: 1.000–1.020 for lag 01) after adjusting the covariates. Stratification analysis conducted in the cold season (October–April) and the warm season (May–September) showed a significant lag 0 effect for AMI cases in the cold season only. Conclusions: In conclusion, acute exposure to PM2.5 was significantly associated with AMI morbidity at lag 0 in Seoul, Korea. This increased risk was also observed at low temperatures.

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Associations between short term exposure to ambient particulate matter from dust storm and anthropogenic sources and inflammatory biomarkers in healthy young adults

The Science of The Total Environment ◽

10.1016/j.scitotenv.2020.144503 ◽

2021 ◽

Vol 761 ◽

pp. 144503

Author(s):

Jalil Jaafari ◽

Kazem Naddafi ◽

Masud Yunesian ◽

Ramin Nabizadeh ◽

Mohammad Sadegh Hassanvand ◽

...

Keyword(s):

Young Adults ◽

Particulate Matter ◽

Dust Storm ◽

Inflammatory Biomarkers ◽

Anthropogenic Sources ◽

Ambient Particulate Matter ◽

Short Term ◽

Short Term Exposure

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Association between lung function of school age children and short-term exposure to air pollution and pollen: the PARIS cohort

Thorax ◽

10.1136/thoraxjnl-2020-215515 ◽

2021 ◽

pp. thoraxjnl-2020-215515

Author(s):

Hélène Amazouz ◽

Nicolas Bougas ◽

Michel Thibaudon ◽

Guillaume Lezmi ◽

Nicole Beydon ◽

...

Keyword(s):

Air Pollution ◽

Lung Function ◽

School Age Children ◽

School Age ◽

Short Term ◽

Short Term Exposure ◽

Air Pollution Exposure ◽

Total Pollen ◽

Pollution Exposure ◽

Cluster 2

BackgroundDaily levels of ambient air pollution and pollen may affect lung function but have rarely been studied together. We investigated short-term exposure to pollen and air pollution in relation to lung function in school-age children from a French population-based birth cohort.MethodsThis study included 1063 children from the PARIS (Pollution and Asthma Risk: an Infant Study) cohort whose lung function and FeNO measurements were performed at age 8 years old. Exposure data were collected up to 4 days before testing. We estimated daily total pollen concentration, daily allergenic risk indices for nine pollen taxa, as well as daily concentrations of three air pollutants (particulate matter less than 10 µm (PM10), nitrogen dioxide (NO2), ozone (O3)). Children with similar pollen and air pollution exposure were grouped using multidimensional longitudinal cluster analysis. Associations between clusters of pollen and air pollution exposure and respiratory indices (FEV1, FVC, FeNO) were studied using multivariable linear and logistic regression models adjusted for potential confounders.ResultsFour clusters of exposure were identified: no pollen and low air pollution (Cluster 1), grass pollen (Cluster 2), PM10 (Cluster 3) and birch/plane-tree pollen with high total pollen count (Cluster 4). Compared with children in Cluster 1, children in Cluster 2 had significantly lower FEV1 and FVC levels, and children from Cluster 3 had higher FeNO levels. For FEV1 and FVC, the associations appeared stronger in children with current asthma. Additional analysis suggested a joint effect of grass pollen and air pollution on lung function.ConclusionDaily ambient chemical and biological air quality could adversely influence lung function in children.

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