Effects of repetitive transcranial magnetic stimulation versus transcutaneous electrical nerve stimulation to decrease diabetic neuropathic pain

2020 ◽  
Vol 27 (2) ◽  
pp. 1-10
Author(s):  
Gehan Mousa Ahmed ◽  
Eman Ahmed Maher ◽  
Bassam Abd Elmaged Mohamed Refaat Elnassag ◽  
Hayam Mahmoud Sayed ◽  
Sara Ibrahim Kabbash

Background/Aims Repetitive transcranial magnetic stimulation and transcutaneous electrical nerve stimulation have been studied repeatedly to reduce diabetic neuropathic pain. The objective of this study was to compare the effects of aerobic training plus one of the treatment therapies on decreasing pain severity in patients with diabetic peripheral neuropathy. Methods A total of 30 patients with diabetic peripheral neuropathy were randomly assigned into two equal groups: group A and group B. Both groups received aerobic training exercises. Group A received repetitive transcranial magnetic stimulation, and Group B received transcutaneous electrical nerve stimulation for 5 consecutive days in 1 week. Outcome measures included pain severity assessment using the Visual Analogue Scale and the serum β-endorphin levels. Results There was a non-significant difference in pre-treatment (P=0.061) and post-treatment (P=0.652) in the Visual Analogue Scale scores between groups. However, β-endorphin levels were significantly different between groups in post- (P=0.015) rather than pre-treatment (P=0.459) levels. A significant moderate correlation between β-endorphin levels and Visual Analogue Scale scores was found in group A (r=−0.6783) at (P=0.008), while it was not significant in group B (r=0.043) at (P=0.883). Conclusions Adding transcutaneous electrical nerve stimulation or repetitive transcranial magnetic stimulation therapies to aerobic training showed similar effects in reducing pain severity in patients with diabetic peripheral neuropathy.

2012 ◽  
Vol 7 (2) ◽  
pp. 29-32
Author(s):  
B Ahmed ◽  
S Alam ◽  
I Rashid ◽  
N Rahman ◽  
A Rahman ◽  
...  

Background: Acute low back pain (LBP) affects a significant proportion of the population. Transcutaneous electrical nerve stimulation (TENS) was introduced more than 30 years ago as an adjunct to the pharmacological management of pain. However, despite its widespread use, the usefulness of TENS in LBP is still controversial. Introduction: LBP is a common problem in Bangladesh. Acute LBP is usually defined by a period of complaints of LBP of six weeks or shorter. TENS may improve acute LBP. Objective: To evaluate the effectiveness of TENS on acute LBP and also to ensure the patients wellbeing by shortening recovery time who have acute LBP. Methods: A prospective study was carried out in the Department of Physical Medicine and Rehabilitation, Bangubandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from July 2008 to December 2008. The patients were divided into two groups (A and B). Patients of Group A (30 patients) were treated with TENS, Non-steroidal anti-inflammatory drugs (NSAIDs) and activities of daily living (ADLs) instruction. Patients of group B (28 patients) were treated with NSAIDs and ADLs instructions. Results: A total of 58 Patients of acute LBP were included in this study. The mean age of the patients was 38.5 ± 9.01 years. Main causes of pain were muscle strain (39.65%), nonspecific LBP (22.41%), prolapsed lumber intervertebral disc (17.24%), lumbar spondylosis (13.79%) and sciatica (6.91%). After treatment the result was compared and student's 't' test was done to see the level of significance. Method was found significant after treatment (p<0.05). Twenty four (80%) patients were improved in group A and 18 (64.28%) patients in group B. Patient compliances of group A were better than that in group B. Conclusion: Effect of TENS on patients with acute low back pain is beneficial. DOI: http://dx.doi.org/10.3329/jafmc.v7i2.10393 JAFMC 2011; 7(2): 29-32


Author(s):  
S Jenifer Augustina ◽  
MG Kaviya ◽  
D Indrani

Background: Restless legs syndrome also known as Willis-Ekbom disease is a sensor motor disorder composed of an urge to move with or without associated discomfort that occurs with inactivity and improves with movement. The symptoms occur in leg muscles like calves and thighs. The feet and arms also affected and it causes the functional disability in pregnant women. Sleep disorder is typically the biggest complication of this condition. Unpleasant sensations are deep in the legs. Sensations appear during periods of rest or inactivity particularly in the evening and at night and relived by movement. Prevalence of RLS among pregnant women ranged from 10 to 34%. Aim: The aim of the study is to prove the effect of Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching and Exercises in restless leg syndrome among pregnant women. Objectives: To determine and prove the effectiveness of TENS with stretching to relive pain and improve the functional ability in restless leg syndrome among pregnant women. Materials and Methods: A Quasi-experimental study was conducted on 30 subjects using convenient sampling technique based on inclusion and exclusion criteria. Subjects were allotted into 2 groups i.e., Group A with 15 subjects and Group B with 15 subjects using odd even method of sampling. Experimental group will be treated with TENS and Stretching. Control group will be treated with exercises and massage. Result: Statistical Analysis of Post test for pain and functional performance revealed that patients who received Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching in Group A showed marked improvement compared to patients who received Massage and Exercises in Group B. Conclusion: From the result of the study it concluded that Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching is more effective than massage and exercises in subjects with restless leg syndrome among pregnant women.


2014 ◽  
Vol 49 (3) ◽  
pp. 411-421 ◽  
Author(s):  
Matthew S. Harkey ◽  
Phillip A. Gribble ◽  
Brian G. Pietrosimone

Objective: To determine the effects of various therapeutic interventions on increasing voluntary quadriceps muscle activation. Background: Decreased voluntary quadriceps activation is commonly associated with knee injury. Recently, research has focused on developing specific disinhibitory interventions to improve voluntary quadriceps activation; yet, it remains unknown which interventions are most effective in promoting this improvement. Data Sources: We searched Web of Science from January 1, 1965 through September 27, 2012, using the key words quadriceps activation and transcutaneous electrical nerve stimulation, transcranial magnetic stimulation, cryotherapy, focal joint cooling, joint mobilization, joint mobilisation, joint manipulation, manual therapy, and neuromuscular electrical stimulation. Study Selection: Studies evaluating the effect of disinhibitory interventions on volitional quadriceps activation were used in our review. Standardized effect sizes (Cohen d) and 95% confidence intervals (CIs) were calculated from voluntary quadriceps activation means and standard deviations measured at baseline and at all available postintervention time points from each study. Data Synthesis: Ten studies were grouped into 5 categories based on intervention type: manual therapy (4 studies), transcutaneous electrical nerve stimulation (2 studies), cryotherapy (2 studies), neuromuscular electrical stimulation (2 studies), and transcranial magnetic stimulation (1 study). Transcutaneous electrical nerve stimulation demonstrated the strongest immediate effects (d = 1.03; 95% CI = 0.06, 1.92) and long-term effects (d = 1.93; 95% CI = 0.91, 2.83). Cryotherapy (d = 0.76; 95% CI = −0.13, 1.59) and transcranial magnetic stimulation (d = 0.54; 95% CI = −0.33, 1.37) had moderate immediate effects in improving voluntary quadriceps activation, whereas manual therapy (d = 0.38; 95% CI = −0.35, 1.09) elicited only weak immediate effects. Neuromuscular electrical stimulation produced weak negative to strong positive effects (range of d values = −0.50 to 1.87) over a period of 3 weeks to 6 months. Conclusions: Transcutaneous electrical nerve stimulation demonstrated the strongest and most consistent effects in increasing voluntary quadriceps activation and may be the best disinhibitory intervention for improving the same.


2020 ◽  
Vol 33 (3) ◽  
pp. 137-139
Author(s):  
X. Moisset ◽  
J. Mawet ◽  
G. Mick

Des techniques de neuromodulation, dont certaines sont bien connues pour leur utilisation dans le cadre de la douleur chronique, ont été développées pour le traitement de la crise migraineuse, et pourraient élargir notre palette thérapeutique. Cette brève revue de la littérature présente ces différentes techniques et les résultats des études principales les évaluant, ainsi que leurs conditions d’accès. En particulier, l’intérêt de la REN (remote electrical neuromodulation), de la rTMS (single pulse transcranial magnetic stimulation) et du TENS (transcutaneous electrical nerve stimulation), techniques disposant d’un dispositif portatif rendant leur utilisation possible en pratique courante, sont évoqués. Les limitations des études et l’intérêt d’études complémentaires pour confirmer l’effet bénéfique de ces traitements ou pour en définir la place dans la stratégie thérapeutique sont également abordés.


2021 ◽  
Vol 9 (10) ◽  
pp. 2324-2330
Author(s):  
Pavitra Pavitra ◽  
Shaila Borannavar ◽  
Ananta. S. Desai ◽  
Samata Samata

Gridhrasi is a Vata Nanatmaja Vyadhi characterized by Ruk (pain), Toda (pricking pain), Stambha (stiffness) and Spandana (frequents twitching). These symptoms initially affect Sphik (buttock) as well as the posterior aspect of Kati (waist) and then gradually radiates to posterior aspects of Uru (thigh), Janu (knee), Jangha (calf) and Pada (foot). It is dominated by pain that affects the Kandara due to morbid Vata Dosha and Kapha Dosha can also be involved in the clinical presentation. Snehana and Swedana are considered as the general line of treatment for Vatavikaras which can be taken as a line of treatment for Gridhrasi. Patra Pinda Sweda being one among Sankara Sweda is Sagni and Snigdha Ruksha type of Sweda. In this medicinal leaves having Vata-Kaphahara, Shothahara and Vedanasthapaka properties are fried in Sahachara Taila and tied into Pottali. Thus, by virtue of its Guna pos- sess the best Snehana and Swedana effect and acts in respective Avasta of the disease Gridhrasi. There are a number of treatments plans available for sciatica. However transcutaneous electrical nerve stimulation (TENS) is a simple, non-invasive analgesic technique that is used extensively in health care settings by physiotherapists for sciatica. The use of conventional transcutaneous electrical nerve stimulation is originally based on the gate control theory of pain and TENS could also raise endorphin levels in the spinal fluid. Methodology: A comparative clinical study was done on forty subjects of both sexes, between the age group of 20-60 years who were randomly assigned into two groups, namely group A where Patra Pinda Sweda was administered to the subjects and group B wheretranscutaneous electrical nerve stimulation was applied to the subjects. After completion of the study, results were assessed using the student 't’ test by comparing the data collected during the study. Result: Comparatively group A proved to be more effective than group B. Group A overall result is 66.73% and Group B overall result is 47.07%. Keywords: Gridhrasi, Physiotherapy, Sahacahara Taila, Snehana, Swedana


PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253040
Author(s):  
Yumeng Zhang ◽  
Shaoyong Wang ◽  
Shulu Zu ◽  
Chanjuan Zhang

Objective We evaluated a combination of transcutaneous electrical nerve stimulation (TENS) and solifenacin succinate versus solifenacin alone in the treatment of overactive bladder (OAB). Methods Ninety-seven female outpatients with OAB were screened for this double-blind randomized controlled study. Eighty-six patients who met our inclusion criteria were divided randomly into two groups. In group A (43 patients), patients received oral solifenacin and “fake” TENS on the foot; in group B (43 patients), patients received oral solifenacin and effective TENS on the foot. Improvements in OAB symptoms were assessed by Overactive Bladder Symptom Score (OABSS), Overactive Bladder Questionnaire (OAB-q), voiding diaries and urodynamic tests. 70 of 86 patients (36 in group A, 34 in group B) completed the 2 months of treatment and 3 months of follow-up. Results Statistically, the maximum bladder volume and OAB symptoms of both groups improved significantly after treatment. The improvement in group B was significantly better than that in group A, as indicated by the maximum bladder volume, OAB-q score and voiding diary. Some mild adverse effects were observed, including dry mouth, stomach upset, constipation, muscle pain and local paresthesia. Conclusion The combination of TENS and solifenacin was more effective in improving OAB symptoms than solifenacin alone.


Author(s):  
Meenakshi Sharma ◽  
Shyamal Koley

The purpose of the present study was to search to search the efficacy of transcutaneous electrical nerve stimulation and therapeutic ultrasound in patients suffering from chronic cervical pain. To fulfill the purpose, A total of randomly selected 30 patients with chronic cervical pain aged 20-70 years were selected from the Physiotherapy Center of Guru Nanak Dev University, Amritsar for the present study. The patients were further randomly divided into two groups, in Group-A, patients were treated with Transcutaneous Electrical Nerve Stimulation (TENS), Therapeutic Ultrasound (TUS), followed  by hot pack, massage, therapeutic exercises (shoulder circumduction, pectoral stretching), cervical stretching, cervical isometrics with the recommendation for daily living activities, whereas, in Group-B, the patient s were treated only with hot pack, massage, therapeutic exercises (shoulder circumduction, pectoral stretching), cervical stretching and cervical isometrics with the recommendation for daily living activities. The outcome measures were Visual Analogue Scale (VAS) for pain, Neck Pain Visual Disability Index (NDI) for disability. The results revealed statistically significant decrease (p<0.001) both in NDI and VAS in patients with cervical pain between pre- and post-intervention in the  Group-A and B, but Group-A showed significantly superior effects both in NDI (82.88% decrement) and VAS (71.62% decrement) than Group-B. In conclusion, it might be stated that transcutaneous electrical nerve stimulation and therapeutic ultrasound were found more effective than conventional physiotherapeutic techniques in relieving pain intensity and disability in patients with chronic cervical pain. Keywords: Transcutaneous Electrical Nerve Stimulation, Therapeutic Ultrasound, Patients with Chronic Cervical Pain.


2018 ◽  
Vol 27 (1) ◽  
pp. 62-67
Author(s):  
Moinuddin Hossain Khan ◽  
Sohely Rahman ◽  
Md Shahadat Hossain ◽  
Muhammad Mahbub Hossain ◽  
Maksuda Khatun ◽  
...  

Context: Osteoarthritis is primarily a disease of cartilage as it is characterized by the degradation of hyaline cartilage in the joints. It is believed to be a dynamic disease that reflects the balance between destruction and repair. Clinically, there is pain, swelling of joints and limitation of motion. Pathological disease is characterized by focal erosive lesions, cartilage destruction, subchondral sclerosis, cyst formation and large osteophyte at the margin of the joints. The objectives of management of osteoarthritis (OA) of the knee are to relieve pain, maintain or improve mobility, and minimize disability. Treatment options include non -pharmacologic intervention, drug therapy, and surgery. Different modalities of physical therapy have been shown to help improve clinical symptoms and function of knee OA with fewer adverse effects. Transcutaneous electrical nerve stimulation (TENS) is among these non invasive therapies which have been used to treat a variety of painful acute and chronic conditions including osteoarthritis. Material and Methods: This randomized clinical trial was conducted on 60 (sixty) patients attending in Physical Medicine and Rehabilitation department of Dhaka Medical College Hospital, who were suffering from knee osteoarthritis. The patients were randomly divided into two groups, Group-A and Group-B. The patients were evaluated clinically and data was collected from both groups in a pre designed data collection sheet for visual analogue scale (VAS) on Pain, 50 feet walking time in seconds and tenderness index in every two weeks interval from the first visit for up to 6 weeks. All the data were analyzed by SPSS version 16.1. Result : The present study showed pain, tenderness and walking time were significantly improved in Group A who were treated with TENS, NSAID & ADL instructions than in Group B who were treated with NSAID & ADL instructions after 6 weeks( P<0.05). Conclusion: The results of this study suggest that application of TENS along with NSAIDs and ADL instructions is more effective in reduction of pain and improving functional performances in patients with knee osteoarthritis than the drug only treatment. J Dhaka Medical College, Vol. 27, No.1, April, 2018, Page 62-67


2021 ◽  
Vol 5 ◽  
pp. 247054702110068
Author(s):  
Cheng-Ta Li ◽  
Chih-Ming Cheng ◽  
Chi-Hung Juan ◽  
Yi-Chun Tsai ◽  
Mu-Hong Chen ◽  
...  

Background Prolonged intermittent theta-burst stimulation (piTBS) and repetitive transcranial magnetic stimulation (rTMS) are effective antidepressant interventions for major depressive disorder (MDD). Cognition-modulated frontal theta (frontalθ) activity had been identified to predict the antidepressant response to 10-Hz left prefrontal rTMS. However, whether this marker also predicts that of piTBS needs further investigation. Methods The present double-blind randomized trial recruited 105 patients with MDD who showed no response to at least one adequate antidepressant treatment in the current episode. The recruited patients were randomly assigned to one of three groups: group A received piTBS monotherapy; group B received rTMS monotherapy; and group C received sham stimulation. Before a 2-week acute treatment period, electroencephalopgraphy (EEG) and cognition-modulated frontal theta changes (Δfrontalθ) were measured. Depression scores were evaluated at baseline, 1 week, and 2 weeks after the initiation of treatment. Results The Δfrontalθ at baseline was significantly correlated with depression score changes at week 1 (r = −0.383, p = 0.025) and at week 2 for rTMS group (r = −0.419, p = 0.014), but not for the piTBS and sham groups. The area under the receiver operating characteristic curve for Δfrontalθ was 0.800 for the rTMS group (p = 0.003) and was 0.549 for the piTBS group (p = 0.619). Conclusion The predictive value of higher baseline Δfrontalθ for antidepressant efficacy for rTMS not only replicates previous results but also implies that the antidepressant responses to rTMS could be predicted reliably at baseline and both piTBS and rTMS could be effective through different neurobiological mechanisms.


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