scholarly journals Improvement of Body Composition and Reduction of Atherogenic Risk Factors during Growth Hormone (GH) Treatment in Children with GH Deficiency (GHD)

1994 ◽  
Vol 3 (Supple5) ◽  
pp. 183-186 ◽  
Author(s):  
Hitoshi Kohno ◽  
Nami Ueyama ◽  
Shinji Yanai ◽  
Koutaro Ukaji ◽  
Sunao Honda
Keyword(s):  
Risk Factors ◽  
Growth Hormone ◽  
Body Composition ◽  
Gh Deficiency ◽  
Gh Treatment

scholarly journals Long-Term Effect of Growth Hormone (GH) Treatment on Body Composition in Children with GH Deficiency

1999 ◽  
Vol 46 (Suppl) ◽  
pp. S35-S38 ◽  
Author(s):  
RYUICHI KUROMARU ◽  
HITOSHI KOHNO ◽  
NAMI UEYAMA ◽  
HASSAN MOHAMED SALAMA HASSAN ◽  
SUNAO HONDA ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Gh Deficiency ◽  
Term Effect ◽  
Gh Treatment ◽  
Long Term Effect

scholarly journals Time for a general approval of growth hormone treatment in adults with Prader–Willi syndrome

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Charlotte Höybye ◽  
◽  
Anthony J. Holland ◽  
Daniel J. Driscoll
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Transition Period ◽  
Neurodevelopmental Disorder ◽  
Hormone Treatment ◽  
Psychomotor Development ◽  
Prader Willi Syndrome ◽  
Gh Treatment ◽  
Beneficial Effects ◽  
Positive Effects

AbstractPrader-Willi syndrome (PWS) is a complex, multi-system, neurodevelopmental disorder characterised by neonatal muscular hypotonia, short stature, high risk of obesity, hypogonadism, intellectual disabilities, distinct behavioural/psychiatric problems and abnormal body composition with increased body fat and a deficit of lean body mass. Growth hormone (GH) deficiency and other hormone deficiencies are common due to hypothalamic dysfunction. In children with PWS GH treatment has been widely demonstrated to improve body composition, normalise height and improve psychomotor development. In adults with PWS, GH’s main effects are to maintain normal body structure and metabolism. The positive effects of GH treatment on body composition, physical fitness and beneficial effects on cardiovascular risk markers, behaviour and quality of life in adults with PWS are also well established from several studies. GH treatment is approved for treatment of children with PWS in many countries, but until recently not as a treatment in young adults in the transition period or for adults in general. In this commentary we want to draw attention to the uneven global use of GH treatment, specifically in adults with PWS, and advocate for GH treatment to be approved internationally, not just for children, but also for adults with PWS and based only on the diagnosis of genetically confirmed PWS.

Body composition, atherogenic risk factors and apolipoproteins following growth hormone treatment

1996 ◽  
Vol 85 (8) ◽  
pp. 899-901 ◽  
Author(s):  
HMS Hassan ◽  
H Kohno ◽  
R Kuromaru ◽  
S Honda ◽  
K Ueda
Keyword(s):  
Risk Factors ◽  
Growth Hormone ◽  
Body Composition ◽  
Growth Hormone Treatment ◽  
Hormone Treatment

Lower ability to oxidize lipids in adult patients with growth hormone (GH) deficiency: reversal under GH treatment

2006 ◽  
Vol 65 (4) ◽  
pp. 423-428 ◽  
Author(s):  
F. Brandou ◽  
I. Aloulou ◽  
A. Razimbaud ◽  
C. Fédou ◽  
J. Mercier ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Gh Deficiency ◽  
Adult Patients ◽  
Gh Treatment ◽  
Lower Ability
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