Abstract
Background: This current study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage Ⅱ to stage Ⅳ by the multilevel modelling analysis.Materials and Methods: A total of 58 patients with chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment and the difference in probing depth was determined [ Reduction of probing depth (Δ PD) = baseline PD - finial probing depth (FPD)]. Three different levels were analyzed: patients, teeth and sites to construct a multi-layer linear model.Results: Probing depth (PD) improved significantly compared with that before treatment (p < 0.05), in which FPD was (3.90±1.39) mm, and the ΔPD was (1.79±0.97) mm. Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5mm or PD < 5mm after the treatment was significantly different (P < 0.05), and the proportion of PD < 5mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels (P <0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers (P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site (P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth (P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD (P < 0.001). Conclusions: Patients with periodontitis from stage Ⅱ to stage Ⅳ, who are non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5mm at baseline, single rooted teeth with hypomobility, less clinical attachment loss and lower bleeding index and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.