scholarly journals Comparing and Investigating the Effects of Bi-level Non-Invasive Ventilator with High and Low Inspiratory Pressure in a Group of Patients Suffering from COPD Exacerbation over the Period of 2015-2016

2016 ◽  
Vol 13 (3) ◽  
pp. 1415-1419
Author(s):  
Farzaneh Ghaemi ◽  
Besharat Rahimi
Keyword(s):  
Inspiratory Pressure ◽  
Copd Exacerbation ◽  
Non Invasive

Long-term non-invasive ventilation to manage persistent ventilatory failure after COPD exacerbation

Respirology ◽  
2010 ◽  
Vol 15 (5) ◽  
pp. 818-822 ◽  
Author(s):  
Nicholas S. OSCROFT ◽  
Timothy G. QUINNELL ◽  
John M. SHNEERSON ◽  
Ian E. SMITH
Keyword(s):  
Copd Exacerbation ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Ventilatory Failure

scholarly journals Non-Invasive Assessment of Inspiratory Ribcage Muscle Fatigue and Recovery During Two Endurance Tests in Healthy Individuals

2021 ◽  
Author(s):  
Thiago Bezerra Wanderley e Lima ◽  
Antonio Sarmento ◽  
Rayane Grayce Silva Vieira ◽  
Esmívany Lhara Freitas Castro ◽  
Francesca Pennati ◽  
...  
Keyword(s):  
Tissue Oxygenation ◽  
Linear Increase ◽  
Inspiratory Pressure ◽  
Median Frequency ◽  
Endurance Test ◽  
Shortening Velocity ◽  
Non Invasive ◽  
Optoelectronic Plethysmography ◽  
Pressure Threshold ◽  
Endurance Tests

Abstract Introduction: Fatigue is defined as a loss in the capacity for developing force and/or velocity of a muscle which is reversible by rest. The aim was to evaluate non-invasively the fatigue and recovery of the inspiratory ribcage muscles during two endurance tests in healthy subjects. Methods: 22 subjects were evaluated before, during and after performing a respiratory endurance test with normocapnic hyperpnea (NH) and inspiratory pressure threshold load (IPTL). Simultaneous measurements of muscle activity (electromyography), tissue oxygenation (NIRS), pressure (nasal inspiratory pressure), and volume (optoelectronic plethysmography) were performed. Results: There was a decrease in the maximum relaxation rate (MRR) and increase in the time constant (τ) after the IPTL test (p <0.05) and a decrease in the peak pressure generated in SNIP after both protocols (p <0.05). Additionally, there was a decrease in shortening velocity and mechanical power only after the IPTL test (p <0.05). The inspiratory ribcage muscles showed a linear drop in the median frequency in the IPTL test and an exponential drop in the NH test, which was not significant for the development of fatigue and there was a linear increase in the NIRS variables in both protocols. Conclusion: It was concluded that the inspiratory ribcage muscles undergo changes after performing an endurance test with NH and IPTL. Additionally, the development of fatigue in these muscles and their consequent changes are more evident in the protocol with IPTL.

The Non-Invasive Ventilation Outcomes (NIVO) score in presumed COPD exacerbation without prior spirometry

2020 ◽  
Author(s):  
Nicholas Lane ◽  
Tom Hartley ◽  
John Steer ◽  
Mark Elliott ◽  
Milind Sovani ◽  
...  
Keyword(s):  
Copd Exacerbation ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Non Invasive Ventilation

scholarly journals Induced sputum in the management of COPD: clinical implications

2015 ◽  
Vol 77 (1) ◽  
Author(s):  
A. Zanini ◽  
S. Della Patrona ◽  
A.L. Facchini ◽  
A. Spanevello
Keyword(s):  
Cell Count ◽  
Airway Inflammation ◽  
Induced Sputum ◽  
First Episode ◽  
Invasive Technique ◽  
Clinical Implications ◽  
Copd Exacerbation ◽  
Sputum Induction ◽  
Non Invasive ◽  
Oral Steroids

Sputum induction can be used as a non-invasive technique to investigate airway inflammation in asthma and COPD. We reported the case of a 68 year old man with COPD, stage III GOLD, that underwent sputum induction during two exacerbation episodes. The first cell count showed a typical sputum neutrophilia, whereas the second showed sputum eosinophilia. On the basis of sputum cellularity, we decided to treat the first episode with a course of antibiotics and the second exacerbation with a course of antibiotics and oral steroids. The patient showed improvement in both cases, obtaining clinical stabilisation. The induced sputum cell count could be a useful technique in a clinical setting to evaluate the cellular characteristics of airway inflammation during COPD exacerbation and modulate the antinflammatory therapy.

Noninvasive Ventilation for Acute COPD Exacerbations

2018 ◽  
pp. 175-179
Author(s):  
Robert Loflin ◽  
David Kaufman
Keyword(s):  
Standard Of Care ◽  
Supplemental Oxygen ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Positive Pressure ◽  
Chronic Obstructive ◽  
Copd Exacerbation ◽  
Obstructive Pulmonary Disease ◽  
Copd Exacerbations ◽  
Non Invasive

In “Non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease,” Brochard and colleagues compared the use of non-invasive positive pressure ventilation (NPPV) to supplemental oxygen delivered by nasal cannula in patients with respiratory failure due to acute COPD exacerbation. The authors found a significant reduction in endotracheal intubation and mechanical ventilation, complications, hospital length of stay, and mortality in the NPPV group. This landmark trial helped establish NPPV as the standard of care for respiratory support in patients with COPD exacerbation. This chapter describes the basics of the study, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. It briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

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