scholarly journals Economic outcomes associated with deep surgical site infection in patients with an open fracture of the lower limb

2018 ◽  
Vol 100-B (11) ◽  
pp. 1506-1510 ◽  
Author(s):  
B. Parker ◽  
S. Petrou ◽  
J. P. M. Masters ◽  
F. Achana ◽  
M. L. Costa
Keyword(s):  
Quality Of Life ◽  
Lower Limb ◽  
Open Fracture ◽  
Site Infection ◽  
Health Related Quality ◽  
Economic Costs ◽  
Related Quality ◽  
Health Related ◽  
Deep Surgical Site Infection

Aims The aim of this study was to estimate economic outcomes associated with deep surgical site infection (SSI) in patients with an open fracture of the lower limb. Patients and Methods A total of 460 patients were recruited from 24 specialist trauma hospitals in the United Kingdom Major Trauma Network. Preference-based health-related quality-of-life outcomes, assessed using the EuroQol EQ-5D-3L and the 6-Item Short-Form Health Survey questionnaire (SF-6D), and economic costs (£, 2014/2015 prices) were measured using participant-completed questionnaires over the 12 months following injury. Descriptive statistics and multivariate regression analysis were used to explore the relationship between deep SSI and health utility scores, quality-adjusted life-years (QALYs), and health and personal social service (PSS) costs. Results Deep SSI was associated with lower EQ-5D-3L derived QALYs (adjusted mean difference -0.102, 95% confidence interval (CI) -0.202 to 0.001, p = 0.047) and increased health and social care costs (adjusted mean difference £1950; 95% CI £1383 to £5285, p = 0.250) versus patients without deep SSI over the 12 months following injury. Conclusion Deep SSI may lead to significantly impaired health-related quality of life and increased economic costs. Our economic estimates can be used to inform clinical and budgetary service planning and can act as reference data for future economic evaluations of preventive or treatment interventions. Cite this article: Bone Joint J 2018;100-B:1506–10.

Social/economic costs and health-related quality of life in patients with fragile X syndrome in Europe

2016 ◽  
Vol 17 (S1) ◽  
pp. 43-52 ◽  
Author(s):  
Karine Chevreul ◽  
◽  
Coralie Gandré ◽  
Karen Berg Brigham ◽  
Julio López-Bastida ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Fragile X Syndrome ◽  
Social Economic ◽  
Fragile X ◽  
Health Related Quality ◽  
Economic Costs ◽  
Related Quality ◽  
Health Related

scholarly journals Biomedical Variables and Adaptation to Disease and Health-Related Quality of Life in Polish Patients with MS

2018 ◽  
Vol 15 (12) ◽  
pp. 2678 ◽  
Author(s):  
Joanna Dymecka ◽  
Mariola Bidzan
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Mood Disorders ◽  
Upper Limb ◽  
Lower Limb ◽  
Health Related Quality ◽  
Neurological Disability ◽  
Related Quality ◽  
Health Related

The aim of this research was to assess the level of adaptation to multiple sclerosis (Sclerosis multiplex; MS) and health-related quality of life (HRQoL) of the study population as well as to determine the relationship between biomedical factors related to the course of multiple sclerosis, adaptation to the disease, and HRQoL. Analysis of medical records, clinical and psychological interviews, the Extended Disability Status Scale (EDSS), Guy’s Neurological Disability Scale (GNDS), the Acceptance of Illness Scale (AIS), and the Multiple Sclerosis Impact Scale 29 (MSIS-29) were collected from 137 patients with MS. It was found that there was a relation between motor impairment, neurological disability, adaptation to illness, and HRQoL; it was also found that there were negative correlations between adaptation to illness and the severity of lower-limb disability, fatigue, mood disorders, other problems related to MS, and upper-limb disability. Of all the symptoms, lower-limb disability, fatigue, and mood disorders had the strongest relation with adaptation. All of the analysed symptoms were found to correlate with HRQoL. Of all the symptoms, HRQoL was most affected by lower- and upper-limb disability, fatigue, other MS problems, and mood disorders.

scholarly journals Economic costs and health-related quality of life for hand, foot and mouth disease (HFMD) patients in China

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0184266 ◽  
Author(s):  
Yaming Zheng ◽  
Mark Jit ◽  
Joseph T. Wu ◽  
Juan Yang ◽  
Kathy Leung ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Health Related Quality ◽  
Economic Costs ◽  
Foot And Mouth ◽  
Related Quality ◽  
Health Related

Social/economic costs and health-related quality of life in patients with Prader-Willi syndrome in Europe

2016 ◽  
Vol 17 (S1) ◽  
pp. 99-108 ◽  
Author(s):  
Julio López-Bastida ◽  
◽  
Renata Linertová ◽  
Juan Oliva-Moreno ◽  
Manuel Posada-de-la-Paz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Economic ◽  
Prader Willi Syndrome ◽  
Health Related Quality ◽  
Economic Costs ◽  
Related Quality ◽  
Health Related

scholarly journals Prevalence of back pain, its effect on functional ability and health-related quality of life in lower limb amputees secondary to trauma or tumour: a comparison across three levels of amputation

2011 ◽  
Vol 35 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Catharina Sjödahl Hammarlund ◽  
Maria Carlström ◽  
Rebecca Melchior ◽  
Björn M Persson
Keyword(s):  
Quality Of Life ◽  
Back Pain ◽  
Lower Limb ◽  
Limb Amputation ◽  
Health Related Quality ◽  
Sf 36 ◽  
High Prevalence ◽  
Related Quality ◽  
Health Related

Background and Objectives: The prevalence of back pain and its effect on function and health-related quality of life across three levels of lower limb amputation secondary to trauma or tumour was studied. Study design: Cross-sectional survey. Methods: Forty-six lower limb amputees, aged 19–78 years, participated. The Roland Morris disability questionnaire (RMDQ) and the short form 36 health survey (SF-36) were used. Results: Participants reported more back pain after amputation than before ( p < 0.001). There was a significant association between back pain daily or several times/week and severe or moderate disability reporting on the RMDQ ( p = 0.003). On the SF-36, the group as a whole scored significantly lower in health-related quality of life with regard to physical functioning, role physical, bodily pain, general health, social functioning and the physical component summary (PCS), and significantly higher in the mental component summary (MCS) compared to normative Swedish data. When all three levels of amputation were compared, no statistically significant differences were found in the RMDQ or SF-36 results. Conclusions: There was a high prevalence of back pain after amputation. Almost all participants having back pain daily or several times per week reported severe or moderate disability on the RMDQ. The group as a whole scored significantly lower for health-related quality of life in the PCS and significantly higher in the MCS compared to normative Swedish data. Clinical relevance The high prevalence of back pain, and the significant association between back pain daily or several times per week and severe or moderate disability on the RMDQ, and the negative correlation between RMDQ and SF-36, may have clinical relevance with regard to rehabilitation and follow-up of lower limb amputation.

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