Doppler-free spectroscopy of molecular iodine using a frequency-stable light source at 578 nm

It is believed by the authors, with supporting experimental evidence, that as little as 0.5°, or less, knife clearance angle may be a critical factor in obtaining optimum quality ultrathin sections. The degree increments located on the knife holder provides the investigator with only a crude approximation of the angle at which the holder is set. With the increments displayed on the holder one cannot set the clearance angle precisely and reproducibly. The ability to routinely set this angle precisely and without difficulty would obviously be of great assistance to the operator. A device has been contrived to aid the investigator in precisely setting the clearance angle. This device is relatively simple and is easily constructed. It consists of a light source and an optically flat, front surfaced mirror with a minute black spot in the center. The mirror is affixed to the knife by placing it permanently on top of the knife holder.

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A confocal laser scanning microscope for fluorescence and reflection at video rates

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100152641 ◽

1989 ◽

Vol 47 ◽

pp. 134-135

Author(s):

P.M. Houpt ◽

A. Draaijer

Keyword(s):

Light Source ◽

Laser Scanning ◽

Focal Point ◽

Confocal Laser Scanning Microscope ◽

Confocal Laser ◽

Point Light Source ◽

Volume Of Interest ◽

Ion Laser ◽

Point Light ◽

Point Detector

In confocal microscopy, the object is scanned by the coinciding focal points (confocal) of a point light source and a point detector both focused on a certain plane in the object. Only light coming from the focal point is detected and, even more important, out-of-focus light is rejected.This makes it possible to slice up optically the ‘volume of interest’ in the object by moving it axially while scanning the focused point light source (X-Y) laterally. The successive confocal sections can be stored in a computer and used to reconstruct the object in a 3D image display.The instrument described is able to scan the object laterally with an Ar ion laser (488 nm) at video rates. The image of one confocal section of an object can be displayed within 40 milliseconds (1000 х 1000 pixels). The time to record the total information within the ‘volume of interest’ normally depends on the number of slices needed to cover it, but rarely exceeds a few seconds.

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Theoretical spectroscopy of molecular iodine. 1. Ab initio study on the B0 u + - X0 g + , A1 u - X0 g + and B'1 u - X0 g + radiative transition intensities

Molecular Physics ◽

10.1080/002689700750036980 ◽

2000 ◽

Vol 98 (23) ◽

pp. 1973-1979 ◽

Cited By ~ 2

Author(s):

A. Zaitsevskii, E. A. Pazyuk, A. V. St

Keyword(s):

Ab Initio ◽

Radiative Transition ◽

Molecular Iodine ◽

Ab Initio Study ◽

Theoretical Spectroscopy

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Inter-Method Reliability of Pulse Volume Related Measures Derived Using Finger-Photoplethysmography

Journal of Psychophysiology ◽

10.1027/0269-8803/a000197 ◽

2018 ◽

Vol 32 (4) ◽

pp. 182-190 ◽

Cited By ~ 4

Author(s):

Kenta Matsumura ◽

Koichi Shimizu ◽

Peter Rolfe ◽

Masanori Kakimoto ◽

Takehiro Yamakoshi

Keyword(s):

Light Intensity ◽

Adverse Effects ◽

Light Source ◽

Direct Current ◽

Resting State ◽

Current Component ◽

Psychophysiological Measures ◽

Pulse Volume ◽

Optical Paths ◽

Sensor Positions

Abstract. Pulse volume (PV) and its related measures, such as modified normalized pulse volume (mNPV), direct-current component (DC), and pulse rate (PR), derived from the finger-photoplethysmogram (FPPG), are useful psychophysiological measures. Although considerable uncertainties exist in finger-photoplethysmography, little is known about the extent of the adverse effects on the measures. In this study, we therefore examined the inter-method reliability of each index across sensor positions and light intensities, which are major disturbance factors of FPPG. From the tips of the index fingers of 12 participants in a resting state, three simultaneous FPPGs having overlapping optical paths were recorded, with their light intensity being changed in three steps. The analysis revealed that the minimum values of three coefficients of Cronbach’s α for ln PV, ln mNPV, ln DC, and PR across positions were .948, .850, .922, and 1.000, respectively, and that those across intensities were .774, .985, .485, and .998, respectively. These findings suggest that ln mNPV and PR can be used for psychophysiological studies irrespective of minor differences in sensor attachment positions and light source intensity, whereas and ln DC can also be used for such studies but under the condition of light intensity being fixed.

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X-ray microscopy by phase-retrieval methods at the advanced light source

Journal de Physique IV (Proceedings) ◽

10.1051/jp4:20030143 ◽

2003 ◽

Vol 104 ◽

pp. 557-561 ◽

Cited By ~ 3

Author(s):

M. R. Howells ◽

H. Chapman ◽

S. Hau-Riege ◽

H. He ◽

S. Marchesini ◽

...

Keyword(s):

Light Source ◽

Phase Retrieval ◽

X Ray ◽

Advanced Light Source

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Organic Light Emitting Diodes - Innovative Light Sources

Light & Engineering ◽

10.33383/2018-157 ◽

2019 ◽

pp. 101-107

Author(s):

Sergei A. Stakharny

Keyword(s):

Light Source ◽

Organic Light Emitting Diodes ◽

Organic Leds ◽

Light Sources ◽

High Quality ◽

Light Emitting ◽

Organic Light ◽

Lighting Systems ◽

Physical Principles ◽

Prospects Of Application

This article is a review of the new light source – organic LEDs having prospects of application in general and special lighting systems. The article describes physical principles of operation of organic LEDs, their advantages and principal differences from conventional non-organic LEDs and other light sources. Also the article devoted to contemporary achievements and prospects of development of this field in the spheres of both general and museum lighting as well as other spheres where properties of organic LEDs as high-quality light sources may be extremely useful.

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ROVIBRATIONAL STUDY OF HNCS PRODUCED VIA ELECTRIC DISCHARGE IN A NEWLY CONSTRUCTED MULTIPASS IR CELL AT THE CANADIAN LIGHT SOURCE SYNCHROTRON

Proceedings of the 74th International Symposium on Molecular Spectroscopy ◽

10.15278/isms.2019.fa04 ◽

2019 ◽

Author(s):

Jennifer van Wijngaarden ◽

Brant Billinghurst ◽

Wenhao Sun ◽

Aimee Bell

Keyword(s):

Light Source ◽

Electric Discharge

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Molecular iodine synergized and sensitized neuroblastoma cells to the antineoplastic effect of ATRA

Endocrine Related Cancer ◽

10.1530/erc-20-0354 ◽

2020 ◽

Vol 27 (12) ◽

pp. 699-710

Author(s):

Irasema Mendieta ◽

Gabriel Rodríguez-Gómez ◽

Bertha Rueda-Zarazúa ◽

Julia Rodríguez-Castelán ◽

Winniberg Álvarez-León ◽

...

Keyword(s):

Residual Disease ◽

Neuroblastoma Cells ◽

Survivin Expression ◽

Body Weight Loss ◽

Immunohistochemical Analysis ◽

Molecular Iodine ◽

Tyrosine Kinase Receptor ◽

Adjuvant Effect

Neuroblastoma (NB) is the most common solid childhood tumor, and all-trans retinoic acid (ATRA) is used as a treatment to decrease minimal residual disease. Molecular iodine (I2) induces differentiation and/or apoptosis in several neoplastic cells through activation of PPARγ nuclear receptors. Here, we analyzed whether the coadministration of I2 and ATRA increases the efficacy of NB treatment. ATRA-sensitive (SH-SY5Y), partially-sensitive (SK-N-BE(2)), and non-sensitive (SK-N-AS) NB cells were used to analyze the effect of I2 and ATRA in vitro and in xenografts (Foxn1 nu/nu mice), exploring actions on cellular viability, differentiation, and molecular responses. In the SH-SY5Y cells, 200 μM I2 caused a 100-fold (0.01 µM) reduction in the antiproliferative dose of ATRA and promoted neurite extension and neural marker expression (tyrosine hydroxylase (TH) and tyrosine kinase receptor alpha (Trk-A)). In SK-N-AS, the I2 supplement sensitized these cells to 0.1 μM ATRA, increasing the ATRA-receptor (RARα) and PPARγ expression, and decreasing the Survivin expression. The I2 supplement increased the mitochondrial membrane potential in SK-N-AS suggesting the participation of mitochondrial-mediated mechanisms involved in the sensibilization to ATRA. In vivo, oral I2 supplementation (0.025%) synergized the antitumor effect of ATRA (1.5 mg/kg BW) and prevented side effects (body weight loss and diarrhea episodes). The immunohistochemical analysis showed that I2 supplementation decreased the intratumoral vasculature (CD34). We suggest that the I2 + ATRA combination should be studied in preclinical and clinical trials to evaluate its potential adjuvant effect in addition to conventional treatments.

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