A Sensitive Chemiluminescence Procedure for the Determination of Carbon Monoxide with Myoglobin—Luminol Chemiluminescence System

2007 ◽  
Vol 61 (7) ◽  
pp. 706-710 ◽  
Author(s):  
Xiaofeng Xie ◽  
Xili He ◽  
Zhenghua Song
Keyword(s):  
Carbon Monoxide ◽  
Injection Technique ◽  
Chemiluminescence Method ◽  
Chemiluminescence Intensity ◽  
Whole Process ◽  
Enhanced Chemiluminescence ◽  
Luminol Chemiluminescence ◽  
Relative Standard ◽  
Artificial Water

A novel chemiluminescence method combined with the flow injection technique for the determination of carbon monoxide is presented in this paper. The chemiluminescence signal based on the reaction between myoglobin and luminol in an alkaline medium was remarkably enhanced by carbon monoxide. The enhanced chemiluminescence intensity was linear with carbon monoxide concentration in the range from 0.01 to 10.0 pmol·L−1, and the detection limit was 3 × 10−3 pmol·L−1 (3σ). The whole process, including sampling and washing, could be completed in 0.5 min with a relative standard deviation of less than 4.0%. The proposed method was applied successfully in the assay of carbon monoxide in human serum and artificial water samples without any pretreatment procedure.

scholarly journals Determination of Organophosphorous Pesticide Phosphamidon in Environmental Water with Luminol Chemiluminescence Detection

2009 ◽  
Vol 92 (3) ◽  
pp. 914-918 ◽  
Author(s):  
Aifang Li ◽  
Xiaoyu Liu ◽  
Juan Kong ◽  
Haoyu Hu ◽  
Linghui Sun ◽  
...  
Keyword(s):  
Sodium Dodecyl ◽  
Sodium Dodecyl Benzene Sulfonate ◽  
Environmental Water ◽  
Optimum Conditions ◽  
Chemiluminescence Method ◽  
Luminol Chemiluminescence ◽  
Relative Standard ◽  
Organophosphorous Pesticide ◽  
Dodecyl Benzene Sulfonate

Abstract A novel chemiluminescence method has been developed for the determination of the organophosphorous pesticide phosphamidon in environmental water samples, based on the reaction of phosphamidon with luminolH2O2 in an alkaline medium using sodium dodecyl benzene sulfonate as the enhancer. Under optimum conditions, the increased chemiluminescence intensity was proportional to the concentration of phosphamidon in the range of 0.011.0 g/mL and the detection limit was 0.0038 g/mL (3). The relative standard deviation was <2 for 0.5 g/mL phosphamidon (n = 11). The proposed method was applied to the determination of phosphamidon residue in an environmental water sample with satisfactory results. Further study was focused on the mechanism of phosphamidon, and a possible mechanism was proposed.

A chemiluminescence method for the determination of verapamil hydrochloride in pharmaceutical and environmental samples based on an Fe3O4 nanoparticles enhanced NaHCO3–H2O2 system

2017 ◽  
Vol 9 (47) ◽  
pp. 6705-6712 ◽  
Author(s):  
Mortaza Iranifam ◽  
Nasim Rahmati Hendekhale
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Environmental Samples ◽  
Chemiluminescence Method ◽  
Verapamil Hydrochloride ◽  
Enhanced Chemiluminescence ◽  
System P ◽  
H2o2 System

In this work, an Fe3O4 nanoparticles (NPs)-enhanced chemiluminescence (CL) method was developed for the determination of verapamil hydrochloride (VRP).

scholarly journals Determination of phenobarbital in human urine and serum usingflow injection chemiluminescence

2012 ◽  
Vol 58 (1) ◽  
pp. 88-94
Author(s):  
K. Li ◽  
L.Z. Nu ◽  
K.L. Khe ◽  
K.H. Song
Keyword(s):  
Human Urine ◽  
Pharmaceutical Preparations ◽  
Injection System ◽  
Chemiluminescence Method ◽  
Chemiluminescence Intensity ◽  
Complete Determination ◽  
Flow Injection System ◽  
Human Urine And Serum ◽  
Urine And Serum

A sensitive chemiluminescence method, based on the enhancive effect of phenobarbital on the chemiluminescence reaction between luminol and dissolved oxygen in a flow injection system, was proposed for the determination of phenobarbital. The chemiluminescence intensity responded to the concentration of phenobarbital linearly ranging from 0.05 to 10 ng⋅ml-1 with the detection limit of 0.02 ng⋅ml-1 (3σ). At a flow rate of 2.0 ml⋅min-1, a complete determination of phenobarbital, including sampling and washing, could be accomplished in 0.5 min, offering the sampling efficiency of 120 h-1 accordingly. The method was applied successfully in an assay of PB for pharmaceutical preparations, human urine and serum without any pretreatment with recovery from 95.7 to 106.7% and RSDs of less than 3.0%.

Permanganate Based Chemiluminescence Analysis of Cefoperazon

2013 ◽  
Vol 333-335 ◽  
pp. 1807-1810
Author(s):  
De Yi Zhang ◽  
Li Wen Zheng
Keyword(s):  
Excited State ◽  
Standard Deviation ◽  
Potassium Permanganate ◽  
Injection Technique ◽  
Pharmaceutical Samples ◽  
Analysis Process ◽  
Relative Standard ◽  
Novel Method ◽  
Emitting Species

In this paper, a novel method fog determination of chemiluminescence (CL) spectra utilizing LS55 luminescence spectrophotometer was proposed. By this means, the CL spectra generated from the oxidation of cephalosporins with potassium permanganate was investigated. The result indicated that acid potassium permanganate CL system has more then three emitting species, excited state Mn(Ⅱ), Mn(Ⅲ) and singlet oxygen all could be assigned as the possible emitting species of this CL system. Base on above investigation results, sodium cefoperazone in pharmaceutical samples was determined by a CL analysis process combining with flow-injection technique. The detection limits estimated by a conservative model (3σ) of cefoperazone was 0.1µg dm-3, and the maximum relative standard deviation (RSD) was not more than 0.8 % (n=11, ρ=20µg dm-3).

Determination of norfloxacin in pharmaceuticals, human serum, and urine using a luminol—dissolved oxygen chemiluminescence system

2007 ◽  
Vol 61 (5) ◽  
Author(s):  
X. Shao ◽  
H. Liu ◽  
X. Gao ◽  
W. Chen ◽  
Z. Song
Keyword(s):  
Dissolved Oxygen ◽  
Calibration Graph ◽  
Injection System ◽  
Chemiluminescence Method ◽  
Relative Standard ◽  
Flow Injection System ◽  
Human Urine And Serum ◽  
Urine And Serum ◽  
Mechanism Of The Reaction

AbstractA sensitive chemiluminescence method, based on the enhancive effect of norfloxacin on the reaction between luminol and dissolved oxygen in a flow injection system, was proposed for the determination of norfloxacin. The increment of the chemiluminiscence intensity was proportional to the concentration of norfloxacin, giving a calibration graph linear over the concentration from 0.4 ng mL−1 to 400.0 ng mL−1 (r 2 = 0.9988) with the detection limit of 0.1 ng mL−1 (3 × σ noise). At the flow rate of 2.0 mL min−1, a complete determination of norfloxacin, including sampling and washing, could be accomplished in 30 s with the relative standard deviation lower than 3.0 %. The proposed method was applied successfully to determine norfloxacin in pharmaceuticals, human urine, and serum. Possible mechanism of the reaction was also discussed.

Gas Chromatographic-Chemiluminescence Method for Determination of Volatile NNitrosamines in Minced Fish-Meat and Surimi-Meat Frankfurters: Collaborative Study

1990 ◽  
Vol 73 (6) ◽  
pp. 947-952
Author(s):  
John W Pensabene ◽  
Walter Fiddler ◽  
John G Phillips
Keyword(s):  
Extraction Method ◽  
Solid Phase ◽  
Collaborative Study ◽  
Energy Analyzer ◽  
Chemiluminescence Method ◽  
Fish Meat ◽  
Relative Standard ◽  
Minced Fish ◽  
Standard Deviations

Abstract A collaborative study was carried out on a solid-phase extraction method for separating volatile N-nltrosamlnes, particularly N-nltrosodlmethylamlne (NDMA), from combination minced fish or surlml-meat frankfurters with detection by gas chromatography-chemllumlnescence (thermal energy analyzer). The results from the 10 collaborators were evaluated using the most recent AOAC guidelines for determining outliers and for the analysis of variance. For NDMA, repeatability standard deviations, sr, ranged from 0.56 to 2.25; repeatability relative standard deviations, RSDr, ranged from 8.9 to 11.5%. Reproducibility standard deviations, sR, for NDMA ranged from 1.40 to 6.49, and reproducibility relative standard deviations, RSDR, ranged from 24.2 to 28.9%. Our data compared favorably to the reproducibility (RSDR) curve of Horwltz. The method has been adopted official first action by AOAC.

Chemiluminescence Enhancement Effect for the Determination of Acetaminophen with the Catalysis of Manganese Deuteroporphyrin (Mn(III)DP)

2013 ◽  
Vol 575-576 ◽  
pp. 249-252 ◽  
Author(s):  
Ying Jun Chao ◽  
Liang Xiao Xie ◽  
Wei Cao
Keyword(s):  
Detection Limit ◽  
Pharmaceutical Preparations ◽  
Peak Height ◽  
Enhancement Effect ◽  
Optimum Conditions ◽  
Chemiluminescence Intensity ◽  
Relative Standard ◽  
Alkaline Conditions ◽  
Flow Injection Chemiluminescence

It is found thatManganese Deuteroporphyrin (Mn(Ⅲ)DP) can greatly enhance the chemiluminescence intensity of luminol-hydrogen peroxide system in alkaline conditions. Basing on that fact a flow injection chemiluminescence (CL) method has been developed for the determination of acetaminophen. With the peak height as a quantitative parameter applying optimum conditions, the relative CL intensity was linear with acetaminophen concentration in the range of 1.0×10-9～1.0×10-7 g/mL with a detection limit of 2.8×10-10 g/mL. The relative standard deviation (RSD) was 2.7% for 2.0 x10-8 g/mL acetaminophen (n = 11). The proposed method held low detection limit and was successfully applied to determination of acetaminophen in pharmaceutical preparations.

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