scholarly journals Adherence Support Workers: A Way to Address Human Resource Constraints in Antiretroviral Treatment Programs in the Public Health Setting in Zambia

PLoS ONE ◽  
2008 ◽  
Vol 3 (5) ◽  
pp. e2204 ◽  
Author(s):  
Kwasi E. Torpey ◽  
Mushota E. Kabaso ◽  
Liya N. Mutale ◽  
Mpuma K. Kamanga ◽  
Albert J. Mwango ◽  
...  
Health Policy ◽  
2011 ◽  
Vol 99 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Susan Cleary ◽  
Sheetal Silal ◽  
Stephen Birch ◽  
Henri Carrara ◽  
Victoria Pillay-van Wyk ◽  
...  

2014 ◽  
Vol 15 (3) ◽  
pp. 77-78 ◽  
Author(s):  
Nathan Geffen ◽  
M Robinson ◽  
F Venter ◽  
M Low

Advances in antiretroviral treatment mean that patients in the public health system can be given more options in the management of their treatment. Although public health programmes tend to offer one-size-fits-all approaches, patients might benefit from a more flexible approach. In particular, we propose that people with HIV should be given more choice with regard to when to start treatment, and patients who experience efavirenz side-effects should be encouraged to switch to other medications, which will be facilitated by faster registration and lower prices of newer antiretrovirals. 


Author(s):  
Marta Aguilar Rodríguez ◽  
Mercè Balasch-Bernat ◽  
Maria-Arantzazu Ruescas-Nicolau ◽  
Anna Arnal-Gómez ◽  
Laura Fuentes-Aparicio

2019 ◽  
Vol 5 (Supplement_1) ◽  
Author(s):  
David Hodgson ◽  
Stéphane Hué ◽  
Jasmina Panovska-Griffiths ◽  
Atila Iamarino ◽  
Katherine E Atkins

Abstract Antiretroviral treatment (ART) has provided substantial benefits for HIV-1-infected patients and has reduced incidence in areas with high uptake since its introduction in the late 1980s. As ART has led to shifts in the worldwide epidemiology of HIV-1, it may also have the potential to cause concomitant selective pressure on the virus population. Evidence for changes in HIV-1 virulence since the introduction of ART appears to be inconsistent. As well as reviewing both empirical and theoretical studies on the likely impact of ART on HIV-1 virulence, we developed a mathematical framework to evaluate the likely impact of ART on virulence selection under the widespread treatment programs and the future impact of recent test-and-treat recommendations. By quantifying both the relationship between virulence changes with the transmissibility through disease progression and the speed of diagnosis and treatment, we reconcile observational studies on virulence changes with the mathematical model predictions. On adoption of new test-and-treat programs—synonymous with early detection and immediate treatment—it is likely that increased virulence will be observed. Our findings highlight the potential public health consequences of mass treatment and the ensuing requirement for greater access and adherence to nullify the public health effect of these virulence changes.


2013 ◽  
Vol 89 (Suppl 1) ◽  
pp. A105.3-A106
Author(s):  
A Lucht ◽  
D Münstermann ◽  
H J Hagedorn ◽  
C Tiemann ◽  
S Kuttner-May

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