scholarly journals HIV-1 Specific Antibody Titers and Neutralization among Chronically Infected Patients on Long-Term Suppressive Antiretroviral Therapy (ART): A Cross-Sectional Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e85371 ◽  
Author(s):  
Johannes S. Gach ◽  
Chad J. Achenbach ◽  
Veronika Chromikova ◽  
Baiba Berzins ◽  
Nina Lambert ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Specific Antibody ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Antibody Titers ◽  
Hiv 1

scholarly journals Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and rectal reservoirs

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Eva Malatinkova ◽  
Ward De Spiegelaere ◽  
Pawel Bonczkowski ◽  
Maja Kiselinova ◽  
Karen Vervisch ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Treatment Initiation ◽  
Cross Sectional Study ◽  
Functional Cure ◽  
Cross Sectional ◽  
Polymerase Chain ◽  
Low Levels ◽  
Rectal Biopsies ◽  
Hiv 1

Persistent reservoirs remain the major obstacles to achieve an HIV-1 cure. Prolonged early antiretroviral therapy (ART) may reduce the extent of reservoirs and allow for virological control after ART discontinuation. We compared HIV-1 reservoirs in a cross-sectional study using polymerase chain reaction-based techniques in blood and tissue of early-treated seroconverters, late-treated patients, ART-naïve seroconverters, and long-term non-progressors (LTNPs) who have spontaneous virological control without treatment. A decade of early ART reduced the total and integrated HIV-1 DNA levels compared with later treatment initiation, but not reaching the low levels found in LTNPs. Total HIV-1 DNA in rectal biopsies did not differ between cohorts. Importantly, lower viral transcription (HIV-1 unspliced RNA) and enhanced immune preservation (CD4/CD8), reminiscent of LTNPs, were found in early compared to late-treated patients. This suggests that early treatment is associated with some immunovirological features of LTNPs that may improve the outcome of future interventions aimed at a functional cure.

scholarly journals First-line antiretroviral therapy and dyslipidemia in people living with HIV-1 in Cameroon: a cross-sectional study

2011 ◽  
Vol 8 (1) ◽  
pp. 33 ◽  
Author(s):  
Eric Pefura Yone ◽  
Awa Betyoumin ◽  
André Kengne ◽  
François Kaze Folefack ◽  
Jeanne Ngogang
Keyword(s):  
Antiretroviral Therapy ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Sectional Study ◽  
First Line ◽  
Cross Sectional ◽  
Living With Hiv ◽  
Hiv 1

scholarly journals Predicting Virologic Failure Among HIV-1-Infected Children Receiving Antiretroviral Therapy in Tanzania: a Cross-Sectional Study

2010 ◽  
Vol 54 (4) ◽  
pp. 368-375 ◽  
Author(s):  
Susan D Emmett ◽  
Coleen K Cunningham ◽  
Blandina T Mmbaga ◽  
Grace D Kinabo ◽  
Werner Schimana ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Virologic Failure ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hiv 1

scholarly journals Vaginal HIV-1 shedding among HIV-1 infected women in the current era of combined antiretroviral therapy: A cross sectional study

Virulence ◽  
2016 ◽  
Vol 8 (1) ◽  
pp. 101-108 ◽  
Author(s):  
Sara Grignolo ◽  
Bianca Bruzzone ◽  
Laura Gabbi ◽  
Daniela Gerbaldo ◽  
Fabio Gallo ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Combined Antiretroviral Therapy ◽  
Hiv 1

scholarly journals Randomized Cross-Sectional Study to Compare HIV-1 Specific Antibody and Cytokine Concentrations in Female Genital Secretions Obtained by Menstrual Cup and Cervicovaginal Lavage

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0131906 ◽  
Author(s):  
Derseree Archary ◽  
Lenine J. Liebenberg ◽  
Lise Werner ◽  
Sahil Tulsi ◽  
Nelisile Majola ◽  
...  
Keyword(s):  
Specific Antibody ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cervicovaginal Lavage ◽  
Hiv 1 ◽  
Female Genital

scholarly journals Decreased NK Cell FcRγ in HIV-1 Infected Individuals Receiving Combination Antiretroviral Therapy: a Cross Sectional Study

PLoS ONE ◽  
2010 ◽  
Vol 5 (3) ◽  
pp. e9643 ◽  
Author(s):  
Edwin Leeansyah ◽  
Jingling Zhou ◽  
Geza Paukovics ◽  
Sharon R. Lewin ◽  
Suzanne M. Crowe ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Nk Cell ◽  
Cross Sectional Study ◽  
Combination Antiretroviral Therapy ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hiv 1

scholarly journals A Cross-Sectional Study on the Impacts of Perceived Job Value, Job Maintenance, and Social Support on Burnout among Long-Term Care Staff in Hawaii

2021 ◽  
Vol 18 (2) ◽  
pp. 476
Author(s):  
Bum Jung Kim ◽  
Sun-young Lee
Keyword(s):  
Social Support ◽  
Long Term Care ◽  
Cross Sectional Study ◽  
Care Staff ◽  
Hierarchical Regression ◽  
Sectional Study ◽  
Cross Sectional ◽  
Term Care ◽  
The Impact

Extensive research has demonstrated the factors that influence burnout among social service employees, yet few studies have explored burnout among long-term care staff in Hawaii. This study aimed to examine the impact of job value, job maintenance, and social support on burnout of staff in long-term care settings in Hawaii, USA. This cross-sectional study included 170 long-term care staff, aged 20 to 75 years, in Hawaii. Hierarchical regression was employed to explore the relationships between the key independent variables and burnout. The results indicate that staff with a higher level of perceived job value, those who expressed a willingness to continue working in the same job, and those with strong social support from supervisors or peers are less likely to experience burnout. Interventions aimed at decreasing the level of burnout among long-term care staff in Hawaii may be more effective through culturally tailored programs aimed to increase the levels of job value, job maintenance, and social support.

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