scholarly journals Biliary Endoprosthesis: A Prospective Analysis of Bacterial Colonization and Risk Factors for Sludge Formation

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e110112 ◽  
Author(s):  
Jochen Schneider ◽  
Alexander Hapfelmeier ◽  
Julia Fremd ◽  
Philipp Schenk ◽  
Andreas Obermeier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bacterial Colonization ◽  
Prospective Analysis ◽  
Sludge Formation ◽  
Biliary Endoprosthesis

IS THERE STILL A DIFFICULT LAPAROSCOPIC CHOLECYSTECTOMY? — AN EXPLORATIVE AND DESCRIPTIVE STUDY TO IDENTIFY RISK FACTORS AND TO ESTABLISH A SCORING SYSTEM FOR DIFFICULT LAPAROSCOPIC CHOLECYSTECTOMY.

2021 ◽  
pp. 52-54
Author(s):  
Suhas Umakanth ◽  
Srinath Subbarayappa ◽  
Jayanth Bannur Nagaraja
Keyword(s):  
Risk Factors ◽  
Laparoscopic Cholecystectomy ◽  
Gallstone Disease ◽  
Descriptive Study ◽  
Gastrointestinal Illness ◽  
Prospective Analysis ◽  
Open Conversion ◽  
Patient Demographics ◽  
Low Threshold ◽  
Distended Gallbladder

Background: Gallstone disease is among the most common gastrointestinal illness requiring hospitalization. Laparoscopic cholecystectomy is now the preferred approach to its treatment. When performing laparoscopic cholecystectomy, the surgeon should have the low threshold for open conversion in case of difculty. The aim of the study was Pre-operative prediction of difcult laparoscopic cholecystectomy using clinical, ultrasonographic and intraoperative parameters. Methods:This study was done on 200 patients presenting with symptomatic cholelithiasis who underwent laparoscopic cholecystectomy. A prospective analysis of parameters including the patient demographics, laboratory values, radiologic data and intraoperative parameters was performed. Results: The factors which were considered a difculty parameter were males, age>60years, preoperative ERCP, rised amylase, sonographic features of contracted or distended gallbladder and pericholecystic collection. Intraoperative parameters were adhesions around gallbladder, contracted or distended gallbladder inamed gallbladder. Conclusions: The above mentioned factors must be adequately studied and the surgeon and the patient should be prepared for difcult laparoscopic cholecystectomy.

scholarly journals Poor Physical Capacity in Bronchiectasis Patients Is Correlated with Poor Quality of Life

2021 ◽  
Author(s):  
Jarkko Mäntylä ◽  
Tanja Törölä ◽  
Witold Mazur ◽  
Paula Bergman ◽  
Paula Kauppi
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Disease Severity ◽  
Bacterial Colonization ◽  
Severe Disease ◽  
Poor Quality ◽  
Physical Capacity ◽  
Bacterial Colonisation ◽  
Cross Sectional

Abstract BackgroundTo study the risk factors associated with quality of life (QoL) in a cohort of Finnish non-cystic fibrosis bronchiectasis (BE) patients. We aimed to evaluate which of the clinical characteristics were risk factors for poor quality of life, how patients with frequent exacerbations differed from those with only few exacerbations and if QoL symptom domains were correlated with dyspnoea or severity of BE.MethodsA cross-sectional study and part of the EMBARC study including questionnaire data and medical record data. Study participants were recruited between August 2016 and March 2018 from three different pulmonary clinics in Helsinki University Central Hospital (HUH) catchment area, Finland. The study included 95 adult patients with (mean age was 69 (SD± 13) years).A Finnish translation of the disease-specific quality of life-bronchiectasis (QoL-B) questionnaire was applied, and scores in the lowest quarter (25%) of the scale were considered to indicate poor QoL. The bronchiectasis severity index (BSI) and FACED (including FEV1, age, pulmonary bacterial colonization, affected lobes and dyspnoea) score were used. The severity of dyspnoea was examined using the modified Medical Research Council (mMRC) dyspnoea scale.ResultsAlmost all (82%) presented with chronic sputum production and exacerbations, with a median rate of 1.7 (SD ±1.6). Exacerbations (OR 1.7, p < 0.01), frequent exacerbations (OR 4.9, p < 0.01), high BSI score (OR 1.3, p < 0.01) and extensive disease (OR 3.7, p = 0.05) were predictive of poor QoL. Frequent exacerbations were associated with bronchial bacterial colonisation, low forced expiratory volume in one second (FEV1) and radiological disease severity. Based on the BSI, 34.1% of our cohort had severe disease, whereas 11.6% were classified as severe according to the FACED score. The mMRC dyspnoea score (r = -0.57) and BSI (r = -0.60) were negatively correlated with physical domain in QoL-B questionnaire. ConclusionFrequent exacerbations, radiological disease severity and high BSI score were predictive of poor QoL. Reduced physical capacity was correlated with dyspnoea and severity of disease. Interventions to reduce bacterial colonisation and to maintain physical functioning should be used to minimize exacerbations and to improve quality of life in BE patients.Study registrationUniversity of Helsinki, faculty of medicine; 148/16.08.2017

scholarly journals Prospective Analysis of Psychiatric Risk Factors in Marines Sent to War

2009 ◽  
Vol 174 (7) ◽  
pp. 737-744 ◽  
Author(s):  
Gerald E. Larson ◽  
Stephanie Booth-Kewley ◽  
Robyn M. Highfill-McRoy ◽  
Sylvia Y. N. Young
Keyword(s):  
Risk Factors ◽  
Prospective Analysis

Risk factors associated with gallstone and biliary sludge formation during pregnancy

2006 ◽  
Vol 21 (7) ◽  
pp. 1150-1153 ◽  
Author(s):  
Filiz F Bolukbas ◽  
Cengiz Bolukbas ◽  
Mehmet Horoz ◽  
Ali T Ince ◽  
Ali Uzunkoy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sludge Formation ◽  
Factors Associated ◽  
Biliary Sludge

scholarly journals Bacterial Colonization in Patients with Chronic Lymphocytic Leukemia and Factors Associated with Infections and Colonization

2019 ◽  
Vol 8 (6) ◽  
pp. 861 ◽  
Author(s):  
Izabela Korona-Glowniak ◽  
Ewelina Grywalska ◽  
Agnieszka Grzegorczyk ◽  
Jacek Roliński ◽  
Andrzej Glowniak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Lymphocytic Leukemia ◽  
Healthy Volunteers ◽  
Bacterial Colonization ◽  
Disease Incidence ◽  
Staging System ◽  
Lymphocytic Leukemia ◽  
Upper Respiratory Tract ◽  
Humoral And Cellular Immunity ◽  
Barr Virus

Patients with chronic lymphocytic leukemia (CLL) have defects in both humoral and cellular immunity as a result of their underlying malignancy, as well as chemotherapy-related immune suppression. Upper respiratory tract (URT) colonization can be regarded as a major contributor to infection, so the relationship between carriage rates, disease incidence, or antibiotic resistance should be monitored. This prospective study included 50 newly diagnosed, previously untreated patients with CLL and 38 healthy volunteers. A total of 264 samples obtained from anterior nares and oropharynx were microbiologically examined. A significantly higher frequency of S. aureus and Gram-negative bacilli (GNB) colonization in CLL patients was observed in comparison to healthy volunteers. Information regarding baseline characteristics; the Rai staging system; hematological tests results; immunophenotype of basic lymphocyte subsets, including the expression of programmed cell death-1 protein (PD-1) and its ligand (PD-L1); as well as Epstein-Barr virus (EBV) status were determined to analyze risk factors for infections and bacterial colonization. The data represent the basic information for identification of further risk factors of infection and bacterial oropharyngeal colonization in CLL patients. The rate of disease progression within the time from the CLL diagnosis was significantly higher in patients colonized by GNB. This study highlights EBV infection and frequencies of PD-1 positive T CD3+ cells and B cells as risk factors in CLL patients.

scholarly journals Headache outcomes following treatment of unruptured intracranial aneurysms: A prospective analysis

Cephalalgia ◽  
2011 ◽  
Vol 31 (10) ◽  
pp. 1082-1089 ◽  
Author(s):  
Todd J Schwedt ◽  
Robert W Gereau ◽  
Karen Frey ◽  
Evan D Kharasch
Keyword(s):  
Risk Factors ◽  
Intracranial Aneurysms ◽  
Prospective Observational Study ◽  
Prospective Analysis ◽  
Headache Frequency ◽  
Factors Associated ◽  
Aneurysm Treatment ◽  
Unruptured Intracranial Aneurysms ◽  
Potential Risk Factors ◽  
Aneurysm Coiling

Objective: To analyze headache patterns prior to and following treatment of unruptured intracranial aneurysms and identify factors associated with different headache outcomes. Methods: A prospective observational study of patients being treated for unruptured intracranial aneurysms. Headache patterns were established prior to aneurysm treatment and for 6 months following treatment. Factors associated with different headache outcomes were investigated. Results: In all patients ( n = 44), 90-day headache frequency decreased from an average of 31 days prior to aneurysm treatment to 17 days following treatment ( p < 0.001). In patients with active pretreatment headaches ( n = 28), 90-day headache frequency decreased from 49 days to 26 days ( p = 0.002). Headache frequency was reduced in 68% of patients, while 9% of patients had new or worsened headaches following aneurysm treatment. Pretreatment migraine, more severe pretreatment headaches, higher pretreatment trait anxiety, and stent-assisted aneurysm coiling were associated with a lack of headache improvement. Conclusions: The majority of patients with headaches at the time of aneurysm treatment had reductions in headache frequency during the 6 months following treatment. Potential risk factors for poor headache outcomes were identified but need to be studied further.

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