Relationship between Body Mass Composition, Bone Mineral Density, Skin Fibrosis and 25(OH) Vitamin D Serum Levels in Systemic Sclerosis

Abstract Background The aim of the present study was to study longitudinal changes in bone mineral density (BMD), vitamin D, and parathyroid hormone (PTH) levels in females over a 10-year period after laparoscopic Roux-en-Y gastric bypass (LRYGB). Methods Twenty-three women, mean age 43.4 ± 8.7 years and mean body mass index (BMI) 44.6 ± 5.17 kg/m2 at baseline, were included. BMD, BMI, S-calcium, S-25(OH)-vitamin D, and fP-PTH were measured preoperatively and 2, 5, and 10 years postoperatively. Results Ten years after surgery, BMD of the spine and femoral neck decreased by 20% and 25%, respectively. Changes in serum levels of vitamin D, PTH, and calcium over the same period were small. Conclusion After LRYGB with subsequent massive weight loss, a large decrease in BMD of the spine and femoral neck was seen over a 10-year postoperative period. The fall in BMD largely occurred over the first 5 years after surgery.

Download Full-text

Evaluation of bone mineral density and 25-(OH) vitamin D levels in middle-aged and elderly women with recurrent benign paroxysmal positional vertigo

Acta Oto-Laryngologica ◽

10.1080/00016489.2019.1692146 ◽

2019 ◽

Vol 140 (2) ◽

pp. 89-93 ◽

Cited By ~ 2

Author(s):

Zhibin Wang ◽

Guanghui Yao ◽

Xiangming Tao ◽

Jincui Zhang ◽

Ting Zhang ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral ◽

Benign Paroxysmal Positional Vertigo ◽

Elderly Women ◽

Mineral Density ◽

Positional Vertigo ◽

Vitamin D Levels ◽

25 Oh Vitamin D ◽

Paroxysmal Positional Vertigo

Download Full-text

Bone mineral density, vitamin D levels, body mass index and exocrine pancreatic function in patients with chronic pancreatitis

Pancreatology ◽

10.1016/j.pan.2017.08.015 ◽

2017 ◽

Vol 17 (5) ◽

pp. S2

Author(s):

A.D. Polanco Jiménez ◽

A. López Serrano ◽

P. Latorre Año ◽

A. Pascual Romero ◽

M.J. Suárez Dávalos ◽

...

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Vitamin D ◽

Chronic Pancreatitis ◽

Body Mass ◽

Bone Mineral ◽

Exocrine Pancreatic Function ◽

Pancreatic Function ◽

Mineral Density ◽

Vitamin D Levels

Download Full-text

Ultrasound bone mineral density of os calcis – its relationship with bone mineral markers and 25(OH) vitamin D in endemic flurotic and non-flurotic villages

The Journal of Clinical and Scientific Research ◽

10.15380/2277-5706.jcsr.12.038 ◽

2012 ◽

pp. 157-162

Author(s):

Harinarayan CV ◽

◽

Ramalakshmi T ◽

Prasad UV ◽

Kumar EGTV ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral ◽

Mineral Density ◽

Os Calcis ◽

25 Oh Vitamin D ◽

Ultrasound Bone

Download Full-text

D-vitamin-anyagcsere és osteoporosis szisztémás sclerosisban

Orvosi Hetilap ◽

10.1556/650.2017.30816 ◽

2017 ◽

Vol 158 (32) ◽

pp. 1252-1258 ◽

Cited By ~ 2

Author(s):

Szilvia Szamosi ◽

Ágnes Horváth ◽

Zoltán Szekanecz ◽

Gabriella Szűcs

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Systemic Sclerosis ◽

Bone Density ◽

Vitamin D Deficiency ◽

Bone Mineral ◽

Mineral Density ◽

Low Bone Mineral Density ◽

Low Bone Density

Abstract: In the past few years more and more data have become available on the important role of vitamin D in immunological processes and inflammation. The role of vitamin D deficiency in the pathogenesis as well as in disease progression of different autoimmune and inflammatory conditions is suspected. Vitamin D deficiency is prevalent in several autoimmune diseases, including systemic sclerosis. Hypovitaminosis has been found to be associated with low bone mineral density and higher prevalence of osteoporosis in this group of patients. Determinants of low bone density in SSc are poorly understood. Studies have shown the importance of both traditional osteoporotic as well as disease-specific factors (extent of skin involvement, presence of internal organ manifestation, malabsorption, systemic sclerosis subtype, serological profile, medication) in the development of low bone mineral density. The relationship between low bone density in systemic sclerosis patients and the above mentioned risk factors may be more complex and the real role of each factor is unclear. Yet very few studies reported clinically relevant low bone mass outcomes such as fracture risk assessment and fracture associated mortality in scleroderma. This review aims to synthesize data about the essential role of vitamin D in immune homeostasis as well as the prevalence of hypovitaminosis, low bone density, changes in bone turnover markers and presence of osteoporosis in scleroderma patients. Orv Hetil. 2017; 158(32): 1252–1258.

Download Full-text