scholarly journals Effects of physical exercise programs on cognitive function in Parkinson’s disease patients: A systematic review of randomized controlled trials of the last 10 years

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193113 ◽  
Author(s):  
Franciele Cascaes da Silva ◽  
Rodrigo da Rosa Iop ◽  
Laiana Cândido de Oliveira ◽  
Alice Mathea Boll ◽  
José Gustavo Souza de Alvarenga ◽  
...  
2016 ◽  
Vol 24 (3) ◽  
pp. 484-496 ◽  
Author(s):  
Franciele Cascaes da Silva ◽  
Rodrigo da Rosa Iop ◽  
Patrícia Domingos dos Santos ◽  
Lídia Mara Aguiar Bezerra de Melo ◽  
Paulo José Barbosa Gutierres Filho ◽  
...  

2020 ◽  
Vol 9 (4) ◽  
pp. 1038 ◽  
Author(s):  
Ruben D. Hidalgo-Agudo ◽  
David Lucena-Anton ◽  
Carlos Luque-Moreno ◽  
Alberto Marcos Heredia-Rizo ◽  
Jose A. Moral-Munoz

Parkinson’s disease (PD) represents the second most common neurodegenerative disease. Currently, conventional physical therapy is complemented by additional physical interventions with recreational components, improving different motor conditions in people with PD. This review aims to evaluate the effectiveness of additional physical interventions to conventional physical therapy in Parkinson’s disease. A systematic review and meta-analysis of randomized controlled trials were performed. The literature search was conducted in PubMed, Physiotherapy Evidence Database (PEDro), Scopus, SciELO and Web of Science. The PEDro scale was used to evaluate the methodological quality of the studies. A total of 11 randomized controlled trials were included in this review. Five of them contributed information to the meta-analysis. The statistical analysis showed favorable results for dance-based therapy in motor balance: (Timed Up and Go: standardized mean difference (SMD) = −1.16; 95% Confidence Interval (CI):(−2.30 to −0.03); Berg Balance Scale: SMD = 4.05; 95%CI:(1.34 to 6.75)). Aquatic interventions showed favorable results in balance confidence (Activities-Specific Balance Confidence: SMD=10.10; 95%CI:(2.27 to 17.93)). The results obtained in this review highlight the potential benefit of dance-based therapy in functional balance for people with Parkinson’s disease, recommending its incorporation in clinical practice. Nonetheless, many aspects require clarification through further research and high-quality studies on this subject.


Author(s):  
Eduardo Vásquez-Araneda ◽  
Rodrigo Ignacio Solís-Vivanco ◽  
Sandra Mahecha-Matsudo ◽  
Rafael Zapata-Lamana ◽  
Igor Cigarroa

Aim: To characterize physical exercise programs for older adults in Latin America. Methods: This review was conducted in accordance with the PRISMA statement. A search for randomized controlled trials (RCTs) published between the years 2015 and 2020 was performed in the Scopus, MedLine and SciELO databases. Results: A total of 101 RCTs were included. A large percentage of the studies had an unclear risk of bias in the items: selection, performance, detection and attribution. Furthermore, a heterogeneous level of compliance was observed in the CERT items. A total sample of 5013 older adults (79% women) was included. 97% of the studies included older adults between 60–70 years, presenting an adherence to the interventions of 86%. The studies were mainly carried out in older adults with cardiometabolic diseases. Only 44% of the studies detailed information regarding the place of intervention; of these studies, 61% developed their interventions in university facilities. The interventions were mainly based on therapeutic physical exercise (89% of the articles), with a duration of 2–6 months (95% of the articles) and a frequency of 2–3 times a week (95% of the articles) with sessions of 30–60 min (94% of the articles) led by sports science professionals (51% of the articles). The components of physical fitness that were exercised the most were muscular strength (77% of the articles) and cardiorespiratory fitness (47% of the articles). Furthermore, only 48% of the studies included a warm-up stage and 34% of the studies included a cool-down stage. Conclusions: This systematic review characterized the physical exercise programs in older adults in Latin America, as well the most frequently used outcome measures and instruments, by summarizing available evidence derived from RCTs. The results will be useful for prescribing future physical exercise programs in older adults.


PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e100503 ◽  
Author(s):  
Hai-Feng Shu ◽  
Tao Yang ◽  
Si-Xun Yu ◽  
Hai-Dong Huang ◽  
Ling-Li Jiang ◽  
...  

2021 ◽  
Vol 0 (0) ◽  
pp. 1-20
Author(s):  
Elif Sina Atak ◽  
◽  
Dilara Yıldız ◽  
Rümeysa Rabia Kocatürk ◽  
Arzu Temizyürek ◽  
...  

Introduction: Parkinson's disease is the world's second most prevalent neurological disease. In Parkinson’s disease intracytoplasmic neuronal inclusions are observed in enteric neurons in the gastrointestinal tract, and the composition of the intestinal microbiome is altered. These changes correlate with the motor phenotype. A systematic review was conducted to determine the effect of probiotics with individuals with Parkinson’s disease. Methods: Scopus, PubMed, Web of Science, The Cochrane Library, Science Direct and OVID-LWW were searched until April 2021 and total 27.395 records were reached according to inclusion and exclusion criteria with the following outcomes: Parkinson's disease rating; oxidative stress, and gastrointestinal system markers. Data searches, article selection and data extraction assessments were performed according to the PRISMA guidelines. The Jadad scale was used to rate the evidence's quality. Results: The information gathered from 5 randomized controlled trials involving 350 individuals with Parkinson’s disease receiving probiotic supplements. Parkinson’s disease rating and non-motor symptoms test were performed. Oxidative stress (Glutathione, malondialdehyde) and gastrointestinal system symptoms (bowel opening frequency, gut transit time, complete bowel movement, spontaneous bowel movements) were evaulated for 4-12 weeks of usage. Conclusion: While all high-quality studies demonstrate progress, there is currently insufficient data to recommend the use of probiotics for people with Parkinson's disease in clinical practice.


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