scholarly journals Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0223899 ◽  
Author(s):  
Xiaobin Xu ◽  
Yu Huang ◽  
Hao Pan ◽  
Rosalynn Molden ◽  
Haibo Qiu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Multiple Dose ◽  
Pharmacokinetic Studies ◽  
Post Translational Modifications ◽  
Therapeutic Monoclonal Antibody

scholarly journals Analysis of Monoclonal Antibody Sequence and Post-translational Modifications by Time-controlled Proteolysis and Tandem Mass Spectrometry

2015 ◽  
Vol 15 (4) ◽  
pp. 1479-1488 ◽  
Author(s):  
Lichao Zhang ◽  
A. Michelle English ◽  
Dina L. Bai ◽  
Scott A. Ugrin ◽  
Jeffrey Shabanowitz ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Post Translational Modifications ◽  
Antibody Sequence

Extending Mass Spectrometry Contribution to Therapeutic Monoclonal Antibody Lead Optimization: Characterization of Immune Complexes Using Noncovalent ESI-MS

2009 ◽  
Vol 81 (15) ◽  
pp. 6364-6373 ◽  
Author(s):  
Cédric Atmanene ◽  
Elsa Wagner-Rousset ◽  
Martine Malissard ◽  
Bertrand Chol ◽  
Alain Robert ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Immune Complexes ◽  
Lead Optimization ◽  
Esi Ms ◽  
Therapeutic Monoclonal Antibody

scholarly journals Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

2011 ◽  
Vol 83 (22) ◽  
pp. 8391-8395 ◽  
Author(s):  
Santosh G. Valeja ◽  
Nathan K. Kaiser ◽  
Feng Xian ◽  
Christopher L. Hendrickson ◽  
Jason C. Rouse ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Fourier Transform ◽  
Cyclotron Resonance ◽  
Unit Mass ◽  
Ion Cyclotron Resonance ◽  
Therapeutic Monoclonal Antibody ◽  
Ion Cyclotron

Analysis of therapeutic monoclonal antibody glycoforms by mass spectrometry for pharmacokinetics study

Talanta ◽  
2017 ◽  
Vol 165 ◽  
pp. 664-670
Author(s):  
Yuting Cong ◽  
Lianghai Hu ◽  
Zhang Zhang ◽  
Yin Gao ◽  
Mingming Dong ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Therapeutic Monoclonal Antibody ◽  
Pharmacokinetics Study
Sign in / Sign up

Export Citation Format

Share Document