scholarly journals Influenza vaccination coverage and factors associated with severe laboratory-confirmed influenza-related illness in patients receiving care at a tertiary hospital in Catalonia (Spain) during the 2018–2019 epidemic season

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260397
Author(s):  
Guillermo Mena ◽  
Irma Casas ◽  
Cristina Casañ ◽  
Mario Auñón ◽  
Lurdes Matas ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Smoking Status ◽  
Underlying Disease ◽  
Severe Illness ◽  
Epidemic Season ◽  
Severe Influenza ◽  
Epidemiological Characteristics

Introduction Influenza vaccination rates in risk groups remain suboptimal. Evidence supporting a significant association between influenza vaccination and severe illness is limited. Methods We retrospectively analyzed the epidemiological characteristics of out- and inpatients with laboratory-confirmed influenza infection attended during the 2018–19 epidemic season. Influenza vaccination coverage by indication was analyzed. Logistic regression was used to compare the odds of vaccination between severe and non-severe influenza-positive patients. Severe cases were defined as presenting pneumonia, admission to critical care units and/or death. Results The overall vaccination coverage among influenza-positive patients was 30.4%. In subjects with ≥ 1 indication for vaccination, the vaccination coverage was 42.4%. By indication, coverage rates were: 52.5% in patients aged ≥ 59 years, 42.2% in obese patients, 29.2% in immunosuppressed subjects and 6.5% in pregnant women. In patients with underlying chronic diseases, a higher coverage was found in patients with cognitive impairment (77%), muscular dystrophy (63.6%) and renal disease (60.4%). The multivariate logistic regression model showed severe influenza-related illness was associated with a lack of influenza vaccination before seeking care during the 2018–2019 season [0.59 (95%CI 0.36–0.97); p = 0.038], older age [1.01 (95%CI 1.00–1.02); p = 0.009] and current or former smoking status [1.63 (95%CI 0.84–3.18) and 2.03 (95%CI 1.16–3.57); p = 0.031], adjusted by underlying disease. Conclusion Adjusting by age, smoking status and underlying disease, a moderate association between the influenza vaccine and severe laboratory-confirmed influenza-related illness was found in an epidemic season in which there was matching between the vaccine and circulating strains. Protection against complications, especially in older subjects and in those with underlying disease is postulated as one of the strengths of annual influenza vaccination. However, influenza vaccination is a pending issue in these groups, especially in pregnant women and obese people. To avoid suboptimal vaccination coverages, health professionals should recommend the seasonal influenza vaccination according to the annual instructions of the health authorities.

scholarly journals Monitoring of Influenza Vaccination Coverage among Pregnant Women in Germany Based on Nationwide Outpatient Claims Data: Findings for Seasons 2014/15 to 2019/20

Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 485
Author(s):  
Annika Steffen ◽  
Thorsten Rieck ◽  
Anette Siedler
Keyword(s):  
Health Care ◽  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Claims Data ◽  
East Germany ◽  
West Germany ◽  
Prenatal Health ◽  
Severe Influenza ◽  
Increased Risk

Pregnant women and their infants are at increased risk for severe influenza-related complications. A decade has passed since influenza vaccination was first recommended for pregnant women in Germany in 2010; however, monitoring of vaccination coverage (VC) has not yet been implemented for this target group. Using nationwide outpatient claims data, we here provide results on influenza VC among pregnant women in Germany for seasons 2014/15 to 2019/20. For any given season, pregnant women were defined as women who had undergone prenatal health care in at least two consecutive quarters within a season. VC increased from 9.0% in season 2014/15 to 16.6% in 2019/20 (+84%), while most of the increase occurred from season 2016/17 (VC: 9.9%) onwards (+68%). Consistently across seasons, women in east Germany were 40 to 60% more likely to be vaccinated compared to women residing in west Germany. According to age, the highest VC was observed among women aged 35 to <40 years (2019/20: 18.2%). Despite noticeable increases in influenza VC during recent years, overall coverage remains low among pregnant women. Starting with this analysis, VC among pregnant women in Germany will be monitored on a yearly basis in order to detect trends and identify immunization gaps.

Coverage and Timing of Influenza Vaccination Among Privately Insured Pregnant Women in the United States, 2010-2018

2021 ◽  
pp. 003335492110267
Author(s):  
Kai Hong ◽  
Megan C. Lindley ◽  
Fangjun Zhou
Keyword(s):  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Influenza Season ◽  
The United States ◽  
Metropolitan Statistical Area ◽  
Provider Education ◽  
Vaccination Uptake ◽  
Increased Risk ◽  
Privately Insured

Objective Pregnant women are at increased risk of serious complications from influenza and are recommended to receive an influenza vaccination during pregnancy. The objective of this study was to assess trends, timing patterns, and associated factors of influenza vaccination among pregnant women. Methods We used 2010-2018 MarketScan data on 1 286 749 pregnant women aged 15-49 who were privately insured to examine trends and timing patterns of influenza vaccination coverage. We examined descriptive statistics and identified factors associated with vaccination uptake by using multivariate log-binomial and Cox proportional hazard models. Results In-plan influenza vaccination coverage before delivery increased from 22.0% during the 2010-2011 influenza season to 33.2% during the 2017-2018 influenza season. About two-thirds of vaccinated women received the vaccine in September or October during each influenza season. For women who delivered in September through May, influenza vaccination coverage increased rapidly at the beginning of influenza season and flattened after October. For women who delivered in June through August, influenza vaccination coverage increased gradually until February and flattened thereafter. Most vaccinated women who delivered before January received the vaccine in the third trimester. Increased likelihood of being vaccinated was associated with age 31-40, living in a metropolitan statistical area, living outside the South, enrollment in a consumer-driven or high-deductible health plan, being spouses or dependents of policy holders, and delivery in November through January. Conclusions Despite increases during the past several years, vaccination uptake is still suboptimal, particularly after October. Health care provider education on timing of vaccination and recommendations throughout influenza seasons are needed to improve influenza vaccination coverage among pregnant women.

scholarly journals A binary logistic regression IN PREDICTING severe influenza in pregnant women

2019 ◽  
Vol 4 (4) ◽  
pp. 113-116
Author(s):  
D.A. Tarbaeva ◽  
◽  
T.E. Belokrinitskaya ◽  
D.M. Serkin ◽  
◽  
...  
Keyword(s):  
Logistic Regression ◽  
Pregnant Women ◽  
Binary Logistic Regression ◽  
Severe Influenza

scholarly journals Influenza Vaccination Coverage Among Pregnant Women — United States, 2014–15 Influenza Season

2015 ◽  
Vol 64 (36) ◽  
pp. 1000-1005 ◽  
Author(s):  
Helen Ding ◽  
Carla L. Black ◽  
Sarah Ball ◽  
Sara Donahue ◽  
Rebecca V. Fink ◽  
...  
Keyword(s):  
United States ◽  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Influenza Season

scholarly journals Seasonal influenza immunisation in Europe. Overview of recommendations and vaccination coverage for three seasons: pre-pandemic (2008/09), pandemic (2009/10) and post-pandemic (2010/11)

2014 ◽  
Vol 19 (16) ◽  
Author(s):  
J Mereckiene ◽  
S Cotter ◽  
A Nicoll ◽  
P Lopalco ◽  
T Noori ◽  
...  
Keyword(s):  
Older People ◽  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Healthcare Workers ◽  
Seasonal Influenza ◽  
Risk Groups ◽  
European Economic Area ◽  
Clinical Risk ◽  
The Impact

Since 2008, annual surveys of influenza vaccination policies, practices and coverage have been undertaken in 29 European Union (EU)/ European Economic Area (EEA) countries. After 2009, this monitored the impact of European Council recommendation to increase vaccination coverage to 75% among risk groups. This paper summarises the results of three seasonal influenza seasons: 2008/09, 2009/10 and 2010/11. In 2008/09, 27/29 countries completed the survey; in 2009/10 and 2010/11, 28/29 completed it. All or almost all countries recommended vaccination of older people (defined as those aged ≥50, ≥55, ≥59, ≥60 or ≥65 years), and people aged ≥6 months with clinical risk and healthcare workers. A total of 23 countries provided vaccination coverage data for older people, but only 7 and 10 had data for the clinical risk groups and healthcare workers, respectively. The number of countries recommending vaccination for some or all pregnant women increased from 10 in 2008/09 to 22 in 2010/11. Only three countries could report coverage among pregnant women. Seasonal influenza vaccination coverage during and after the pandemic season in older people and clinical groups remained unchanged in countries with higher coverage. However, small decreases were seen in most countries during this period. The results of the surveys indicate that most EU/EEA countries recommend influenza vaccination for the main target groups; however, only a few countries have achieved the target of 75% coverage among risk groups. Coverage among healthcare workers remained low.

scholarly journals The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature

2020 ◽  
Vol 17 (21) ◽  
pp. 7870
Author(s):  
Marco Del Riccio ◽  
Chiara Lorini ◽  
Guglielmo Bonaccorsi ◽  
John Paget ◽  
Saverio Caini
Keyword(s):  
Systematic Review ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
Severe Disease ◽  
Ventilatory Support ◽  
Severe Illness ◽  
Risk Of Infection ◽  
Review Of The Literature ◽  
Support Measures

We reviewed the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g., severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients. None of the studies that were reviewed (n = 12) found a significant increase in the risk of infection or in the illness severity or lethality, and some reported significantly inverse associations. Our findings support measures aimed at raising influenza vaccination coverage in the coming months.

scholarly journals The association between influenza vaccination and the risk of SARS-CoV-2 infection, severe illness, and death: a systematic review of the literature.

2020 ◽  
Author(s):  
Marco Del Riccio ◽  
Chiara Lorini ◽  
Guglielmo Bonaccorsi ◽  
John Paget ◽  
Saverio Caini
Keyword(s):  
Systematic Review ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
Severe Disease ◽  
Ventilatory Support ◽  
Severe Illness ◽  
Risk Of Infection ◽  
Review Of The Literature ◽  
Support Measures

We reviewed the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g. severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients. None of the studies that were reviewed (n=12) found a significant increase in the risk of infection or in the illness severity or lethality, while some reported significantly inverse associations. Our findings support measures aimed at raising influenza vaccination coverage in the coming months.

scholarly journals Altered Influenza Vaccination Coverage and Related Factors in Pregnant Women in Korea from 2007 to 2019

2021 ◽  
Vol 36 (5) ◽  
Author(s):  
Jae Hyoung Im ◽  
Dae Hoon Choi ◽  
Jihyeon Baek ◽  
Hea Yoon Kwon ◽  
Soo Ran Choi ◽  
...  
Keyword(s):  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Related Factors

scholarly journals Influenza vaccination coverage among healthcare workers during the first two seasons of data collection, Finland, 2017-2019

2020 ◽  
Author(s):  
Charlotte C Hammer ◽  
Outi Lyytikäinen ◽  
Dinah Arifulla ◽  
Toura Saija ◽  
Hanna Nohynek
Keyword(s):  
High Risk ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Healthcare Workers ◽  
Risk Groups ◽  
Severe Illness ◽  
Immunocompromised Patients ◽  
Web Based ◽  
The Mean ◽  
Improve Patient

Background: Influenza can cause severe illness among high-risk groups such as elderly and immunocompromised patients. Mandatory influenza vaccination of healthcare workers (HCWs) has been viewed as means to improve patient and HCW protection. Methods: We analyzed data collected by a web-based survey sent annually to all Finnish acute care hospitals and described the influenza vaccination coverage among HCWs during seasons 2017/18 (without mandate) and 2018/19 (mandate enforced). Results: In season 2017/2018, 38/39 hospitals provided data and 35/36 hospitals in 2018/2019. The mean coverage in season 2017/18 was 88% (median, 84%; range 48-100%) and in 2018/19 91% (median, 91%; range 57-100%). The mean increase from season 2017/2018 to 2018/2019 was 6.5% (median, 3%; range -11.0-33.0%). Conclusions: The coverage of influenza vaccinated HCWs in Finnish hospitals was high. However, there were major differences between hospitals which raise the question about data quality as well as implementation of the mandate, and need further evaluation.

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