Recurrent Pseudomonas aeruginosa Pneumonia in an Intensive Care Unit

CHEST Journal ◽  
1992 ◽  
Vol 101 (1) ◽  
pp. 194-198 ◽  
Author(s):  
Daniel R. Silver ◽  
Ian L. Cohen ◽  
Peter F. Weinberg
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care

scholarly journals Epidemiology and characterisation of carbapenem-non-susceptible Pseudomonas aeruginosa in a large intensive care unit in Jakarta, Indonesia

2019 ◽  
Vol 54 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Yulia Rosa Saharman ◽  
Andreu Coello Pelegrin ◽  
Anis Karuniawati ◽  
Rudyanto Sedono ◽  
Dita Aditianingsih ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care

scholarly journals Mechanisms of carbapenem resistance in endemic Pseudomonas aeruginosa isolates after an SPM-1 metallo-β-lactamase producing strain subsided in an intensive care unit of a teaching hospital in Brazil

2016 ◽  
Vol 111 (9) ◽  
pp. 551-558 ◽  
Author(s):  
Luciana Camila Cacci ◽  
Stephanie Gomes Chuster ◽  
Natacha Martins ◽  
Pâmella Rodrigues do Carmo ◽  
Valéria Brígido de Carvalho Girão ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Teaching Hospital ◽  
Carbapenem Resistance

Epidemiology of Nosocomial Outbreaks: 14-Year Experience at a Tertiary-Care Center

2000 ◽  
Vol 21 (8) ◽  
pp. 527-529 ◽  
Author(s):  
Luis Ostrosky-Zeichner ◽  
Rosa Baez-Martinez ◽  
M. Sigfrido Rangel-Frausto ◽  
Samuel Ponce-de-León
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Nosocomial Infections ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Common Organism ◽  
Overall Mortality

Twelve nosocomial outbreaks over 14 years at a tertiary-care center in Mexico are described. Overall mortality was 25.8%, one half due to pneumonia. The most common organism was Pseudomonas aeruginosa. Incidence was three outbreaks per 10,000 discharges; outbreak-related infections comprised 1.56% of all nosocomial infections. Incidence in the intensive care unit was 10-fold higher.

Serratia marcescans Contamination of Antiseptic Soap Containing Triclosan: Implications for Nosocomial Infection

1984 ◽  
Vol 5 (9) ◽  
pp. 427-430 ◽  
Author(s):  
M. Anita Barry ◽  
Donald E. Craven ◽  
Theresa A. Goularte ◽  
Deborah A. Lichtenberg
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Nosocomial Infection ◽  
Surgical Intensive Care Unit ◽  
Minimal Bactericidal Concentration ◽  
Surgical Intensive Care ◽  
Time Kill ◽  
The Impact

Abstract During a recent investigation in our surgical intensive care unit, we found that several bottles of the antiseptic handwashing soap, OR Scrub®, were contaminated with Serratia marcescens. OR Scrub® contains 1% triclosan, lanolin, and detergents. The antimicrobial efficacy of OR Scrub® was examined in vitro using serial two-fold dilutions of soap inoculated with various concentrations of different nosocomial pathogens. The minimal bactericidal concentration (MBC) of OR Scrub® against Pseudomonas aeruginosa and several strains of S. marcescens was ≤1:2 By comparison, a non-antiseptic soap from the same manufacturer (Wash®) and 4% chlorhexidine (Hibiclens®) had MBCs for all strains tested of at least 1:64. Time-kill curves confirmed the findings of the initial experiments.This is the first report of extrinsic contamination of antiseptic soap containing triclosan. No infections could be attributed to the contaminated soap, but sporadic outbreaks of Serratia have occurred in the intensive care unit with no identifiable source. Although there have been few studies on the impact of antiseptic soap in reducing nosocomial infection, we question whether a soap with the limitations of OR Scrub® should be used in intensive care units or operating rooms.

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