scholarly journals Platform image processing to study the structural properties of retinal vessel

Author(s):  
Gabino Verde ◽  
Luis García-Ortiz ◽  
Carolina Zato ◽  
Juan Francisco De Paz ◽  
Sara Rodríguez ◽  
...  

This paper presents a technological platform specialized in assessing retinal vessel caliber and describing the relationship of the results obtained to cardiovascular risk. Retinal circulation is an area of active research by numerous groups, and there is general experimental agreement on the analysis of the patterns of the retinal blood vessels in the normal human retina. The development of automated tools designed to improve performance and decrease interobserver variability, therefore, appears necessary. 

2013 ◽  
Vol 54 (12) ◽  
pp. 7234 ◽  
Author(s):  
Sky K. H. Chew ◽  
Yamna Taouk ◽  
Jing Xie ◽  
Theona E. Nicolaou ◽  
Jie J. Wang ◽  
...  

1946 ◽  
Vol 133 (872) ◽  
pp. 235-248 ◽  

Since a review of the conditions under which siderocytes appear will support a hypothesis that it is an ageing erythrocyte at least as strongly as Grüneberg’s (1941 a ) theory that it should be considered as a young cell, a search was made in blood films of stored mammalian blood and large numbers of siderocytes were found. The conditions affecting the rate of appearance of the siderocytes were studied, and it was found that adverse conditions would hasten their appearance. The relationship of the siderotic material to the 'easily split’ blood iron was also considered, and it seems probable that both are derived from a special and identical fraction of ‘haemoglobin’, and that this phenomenon is related to an intracorpuscular bile pigment formation. The occurrence of siderocytosis after the ingestion of acetyl phenylhydrazine by a ‘normal’ human being was followed, and a close correlation between siderocytosis, erythrocyte destruction and urinary siderosis as described by Peyton Rous (1918) is shown. The siderocyte extrudes its siderotic granules and reverts to a state at present morphologically indistinguishable from the normal erythrocyte, but appears to be susceptible of phagocytosis at this stage. The application of siderocyte counts to clinical medicine is suggested.


2000 ◽  
Vol 6 (7) ◽  
pp. 781-788 ◽  
Author(s):  
JENNIFER SALTZMAN ◽  
ESTHER STRAUSS ◽  
MICHAEL HUNTER ◽  
SARAH ARCHIBALD

Although the majority of research in theory of mind (TOM) has focused on young children or individuals with autism, recent investigations have begun to look at TOM throughout the lifespan and in other neurological and psychiatric populations. Some have suggested that TOM may represent a dissociable, modular brain system that is related to, but separable, from other brain functions including executive functions (EF). Recently, studies have shown that TOM performance can be compromised following an acquired brain insult (e.g, damage to the right hemisphere). However, the relationship of such impaired TOM performance to other brain functions in these cases has not been explored. This study investigated the effects of both normal human aging and Parkinson's disease on TOM. The relationship of TOM performance and EF in these groups was also examined. The results suggested that although TOM performance appeared compromised in the group of individuals with Parkinson's disease, the elderly control participants were relatively unimpaired relative to younger individuals. Significant relationships between several measures of TOM and EF were also found. The implications of these findings, and also the finding that failure on one measure of TOM did not necessarily predict failure on all measures of TOM, are discussed. (JINS, 2000, 6, 781–788.)


Author(s):  
Nico P.M. Smit ◽  
Carlo W.T. van Roermund ◽  
Hans M.F.G. Aerts ◽  
Judith C. Heikoop ◽  
Marlene Van den Berg ◽  
...  

1980 ◽  
Vol 32 (1) ◽  
pp. 3-25 ◽  
Author(s):  
Michael I. Posner

Bartlett viewed thinking as a high level skill exhibiting ballistic properties that he called its “point of no return”. This paper explores one aspect of cognition through the use of a simple model task in which human subjects are asked to commit attention to a position in visual space other than fixation. This instruction is executed by orienting a covert (attentional) mechanism that seems sufficiently time locked to external events that its trajectory can be traced across the visual field in terms of momentary changes in the efficiency of detecting stimuli. A comparison of results obtained with alert monkeys, brain injured and normal human subjects shows the relationship of this covert system to saccadic eye movements and to various brain systems controlling perception and motion. In accordance with Bartlett's insight, the possibility is explored that similar principles apply to orienting of attention toward sensory input and orienting to the semantic structures used in thinking.


Ophthalmology ◽  
2018 ◽  
Vol 125 (11) ◽  
pp. 1784-1792 ◽  
Author(s):  
Ronald Klein ◽  
Kristine E. Lee ◽  
Lorraine Danforth ◽  
Michael Y. Tsai ◽  
Ronald E. Gangnon ◽  
...  

2019 ◽  
Vol 33 (8) ◽  
pp. 530-534
Author(s):  
Barbara E.K. Klein ◽  
Kayla M.L. Horak ◽  
Stacy M. Meuer ◽  
Anne E. Mosher ◽  
Andrew F. Ewen ◽  
...  

1981 ◽  
Vol 27 (11) ◽  
pp. 1856-1861 ◽  
Author(s):  
M Samaja ◽  
A Mosca ◽  
M Luzzana ◽  
L Rossi-Bernardi ◽  
R M Winslow

Abstract We describe a new method for tonometry of small amounts of blood (up to 0.25 mL) at known pO2, PCO2, and temperature, in small, reusable, closed Pyrex flasks. Equilibrated blood is analyzed for oxygen saturation, pH, and organic phosphate concentration with standard techniques, and its p50 (the pO2 at which hemoglobin is half-saturated with oxygen) is determined with full control of all the variables known to affect it. The SD in the measurement of p50 is 0.044 kPa (0.33 mmHg). We made 63 determinations of p50 on normal human blood under different conditions of pH and pCO2, and with different concentrations of 2,3-diphosphoglycerate and ATP. Empirical equations and a nomogram were derived, which allow the calculation of p50 from known values of pCO2, pH, and [2,3-DPG]/[Hb4] molar ratio with a SD of 97 and 114 Pa (0.73 and 0.86 mmHg), respectively.


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