scholarly journals Treatment of In-Patient Pulmonary Tuberculosis

2017 ◽  
Vol 15 (11-12) ◽  
pp. 297
Author(s):  
Rasmin Rasjid
Keyword(s):  
Developing Countries ◽  
Pulmonary Tuberculosis ◽  
Treatment Regimen ◽  
Daily Treatment ◽  
Tuberculous Lesion ◽  
Potent Drug

The progress of a tuberculous lesion was discussed. A treatment regimen of pulmonary tuberculosis in the wards mas layed out, especially for the "Persahabatan" Hospital, Jakarta. Rifampicin seems to be a potent drug. However, for developing countries like Indonesia it is still very expensive. Possibly a combinations of INH + RMP + EB will be most effective at present. Only a daily treatment is carried out in ”Persahabatan” Hospital.

The larynx in pulmonary tuberculosis

1985 ◽  
Vol 99 (2) ◽  
pp. 201-203 ◽  
Author(s):  
M. H. A. Beg ◽  
S. Marfani
Keyword(s):  
Developing Countries ◽  
Pulmonary Tuberculosis ◽  
Posterior Part ◽  
Common Disease ◽  
The World ◽  
Ulcerative Lesions ◽  
Laryngeal Involvement

SummarySummary Pulmonary tuberculosis is still a common disease in the developing countries of the world. One hundred patients with pulmonary tuberculosis showed laryngeal involvement in 37 patients. The posterior part of the larynx followed by the epiglottis are the commonest sites to be involved in the laryx. Ulcerative lesions and perichondritis. so common in prechemotherapeutic days, were not seen.

scholarly journals Multicentre, open label, randomised controlled trial comparing intermittent versus daily treatment for non-cavitary nodular/bronchiectatic Mycobacterium avium complex lung disease with rifampicin, ethambutol and clarithromycin (iREC): study protocol

2019 ◽  
Vol 6 (1) ◽  
pp. e000434 ◽  
Author(s):  
Taku Nakagawa ◽  
Hiroya Hashimoto ◽  
Mitsuaki Yagi ◽  
Yoshihito Kogure ◽  
Masahiro Sekimizu ◽  
...  
Keyword(s):  
Treatment Group ◽  
Lung Disease ◽  
Treatment Regimen ◽  
Mycobacterium Avium ◽  
Drug Combination ◽  
Daily Treatment ◽  
Intermittent Treatment ◽  
Sputum Culture Conversion ◽  
Randomised Controlled ◽  
Culture Conversion

IntroductionStandard treatment for nodular/bronchiectatic Mycobacterium avium complex lung disease (NB MAC-LD), excluding severe-status cases, differs between Japan and other countries. Internationally, three-drug combination intermittent treatment (three times a week administration) with macrolide, ethambutol and rifampicin is recommended, but a daily treatment regimen is recommended in Japan. To date, no randomised controlled study directly comparing intermittent treatment with daily treatment has been performed. The purpose of this study is to investigate the usefulness of intermittent treatment.Methods and analysisA total of 140 patients diagnosed with NB MAC-LD in Japan will be randomly assigned, in a 1:1 ratio, to intermittent treatment group or daily treatment group, and three-drug combination therapy with clarithromycin, rifampicin and ethambutol will be continued for 1 year. The primary endpoint is the proportion of patients requiring modification of the initial treatment regimen. Secondary endpoints are adverse events, sputum culture conversion, time to sputum culture conversion, improvement of chest CT findings, change in health-related quality of life score and development of clarithromycin resistance.Ethics and disseminationThis trial was approved by the National Hospital Organisation Review Board for Clinical Trials (Headquarters). The results of this study will be reported at a society meeting or published in a peer-review journal.

Improved microscopical diagnosis of pulmonary tuberculosis in developing countries

1995 ◽  
Vol 89 (2) ◽  
pp. 191-193 ◽  
Author(s):  
Negussie Gebre ◽  
Ulf Karlsson ◽  
Göran Jönsson ◽  
Ragini Macaden ◽  
Alemnesh Wolde ◽  
...  
Keyword(s):  
Developing Countries ◽  
Pulmonary Tuberculosis

High Patient Compliance On A Once Daily Treatment Regimen With The Hay Fever Drug Grazax

2008 ◽  
Vol 121 (2) ◽  
pp. S128-S128 ◽  
Author(s):  
I SJOLIN ◽  
L HAUGAARD ◽  
T KOPP ◽  
A JANSEN ◽  
H BRUNING ◽  
...  
Keyword(s):  
Treatment Regimen ◽  
Patient Compliance ◽  
Hay Fever ◽  
Daily Treatment ◽  
Once Daily

scholarly journals PROFILE OF SPUTUM POSITIVE PULMONARY TUBERCULOSIS PATIENTS ON RE - TREATMENT REGIMEN

2015 ◽  
Vol 4 (81) ◽  
pp. 14129-14136
Author(s):  
Kiran V H ◽  
Deepak Ramchand Nenwani ◽  
Muralidhara Yadiyal B
Keyword(s):  
Pulmonary Tuberculosis ◽  
Treatment Regimen ◽  
Tuberculosis Patients

scholarly journals STUDI PENGARUH STATUS PERKAWINAN DAN PEKERJAAN PADA PASIEN TUBERKULOSIS DI RUMAH SAKIT DKT PURWOKERTO

2019 ◽  
Vol 10 (2) ◽  
pp. 46-51
Author(s):  
Peppy Octaviani
Keyword(s):  
Infectious Disease ◽  
Developing Countries ◽  
Pulmonary Tuberculosis ◽  
Descriptive Study ◽  
World Health ◽  
P Value ◽  
Cross Sectional ◽  
Pulmonary Tb ◽  
The World ◽  
Health Organization

ABSTRACT Pulmonary tuberculosis (TB) is a contagious pulmonary infectious disease that is still a health problem in the world, especially developing countries. Tuberculosis has been proclaimed by WHO (World Health Organization) as Global Emergency since 1992. The purpose of this study is to find out what physical characteristics are at risk of tuberculosis in DKT Hospital Purwokerto. The research design used in this study was a descriptive study with a cross-sectional approach to determine the characteristics of pulmonary TB patients who were adherent to treatment and those who did not comply with treatment at the DKT Hospital in Purwokerto. This research was conducted at the DKT Purwokerto Hospital in May 2018. The samples studied in this study were pulmonary TB patients who were obedient to treatment and non-compliance with treatment at the DKT Purwokerto Hospital for the period of 1 January - 30 December 2017 that met the sample criteria. The results of the study have no relationship between age and the results of sputum examination at the Purwokerto DKT Hospital (p value = 0.286), there is no relationship between sex with the results of sputum examination at DKT Purwokerto Hospital (p value = 0.261).                                                                                                                           Keywords: Pulmonary TBC, Characteristics, Phlegm Examination  

scholarly journals LONG-TERM OUTCOMES OF TREATMENT IN PATIENTS WITH DRUG-RESISTANT PULMONARY TUBERCULOSIS AND NON-EFFICIENCY OF PREVIOUS THERAPY

2019 ◽  
Vol 24 (2) ◽  
pp. 88-91
Author(s):  
A. I. Elgali ◽  
A. V. Aseev ◽  
Dmitriy S. Riasenskii ◽  
N. A. Grishkina
Keyword(s):  
Pulmonary Tuberculosis ◽  
Treatment Regimen ◽  
Long Term Results ◽  
Drug Resistant ◽  
Adherence To Treatment ◽  
Recommended Treatment ◽  
Results Of Treatment ◽  
Previous Therapy ◽  
Cavity Closure

In 2018 key changes were made to the recommended treatment for multi-drug resistant tuberculosis, the priority of oral medications over injectables was indicated. For the first time in history, a new, completely oral 20-month treatment regimen was proposed. The regimen recommends bedaquiline and linezolid together with levofloxacin / moxifloxacin, cycloserine / clofazimine. This treatment regimen differs from the standard 4 MDR-TB chemotherapy regimens adopted in Russia. Until recently, bedaquiline and linezolid were relatively unobtainable in the conditions of tuberculosis dispensaries, patients who needed such treatment were referred to specialized Federal tuberculosis facilities. The aim of the study was to study the long-term results of treatment of patients with drug-resistant pulmonary tuberculosis in cases of the ineffectiveness of previous therapy in an antituberculosis dispensary and referral to a specialized Federal tuberculosis institution. In 2010-2014, 143 people of both sexes in the age group from 20 to 60 years old were treated in the Tver Regional Clinical Antituberculosis Dispensary. Individual conversations, organizing communication with other patients who received effective anti-tuberculosis treatment, watching the training video “Tuberculosis: Questions and Answers”, studying the materials of the brochure “School of the Patient. A brochure for patients suffering from tuberculosis” developed by the charitable organization “Partners in the name of health” was used in the process of increasing adherence to treatment. When carrying out measures to increase adherence to treatment among patients with pulmonary tuberculosis, a positive result was obtained in 143 people. These patients agreed to possible surgical intervention in the Federal Tuberculosis Institution. Immediately after the surgical stage of treatment, cavity closure and/or abacillation were achieved in 132 (92.3%) people. In the postoperative period anti-tuberculosis therapy was continued in accordance with the drug-resistant pathogen, the discipline of patients in receiving anti-tuberculosis drugs increased significantly.

Evaluation of the Concentration Sputum Smear Technique for the Laboratory Diagnosis of Pulmonary Tuberculosis

2003 ◽  
Vol 33 (3) ◽  
pp. 160-162 ◽  
Author(s):  
Solomon Gebre-Selassie
Keyword(s):  
Developing Countries ◽  
Pulmonary Tuberculosis ◽  
Laboratory Diagnosis ◽  
Sputum Smear ◽  
Smear Microscopy ◽  
Tb Control ◽  
Mycobacterial Diseases ◽  
Control Programmes ◽  
Rate Of Recovery ◽  
Concentration Methods

The microbiological diagnosis of pulmonary tuberculosis (PTB) plays a key role in routine and Tuberculosis (TB) Control Programmes in developing countries. Concentration of acid-fast bacilli (AFB) in clinical specimens is an important step in the laboratory diagnosis of mycobacterial diseases. Microscopy of smears of sputum by direct and after mechanical sedimentation and centrifugation methods followed by treatment with 5% sodium hypochlorite (NaOCl) solution for concentration of the organisms were compared and evaluated. The rate of recovery of AFB from sputum was 8.5%, 25.5% and 38.0% for direct smear microscopy, concentration by sedimentation of NaOCl-treated sputa followed by Ziehl-Neelsen staining and concentration by centrifugation after use of NaOCl respectively. Both the concentration methods by the use of NaOCl solution increased the yield of the AFB by more than threefold compared with the direct microscopy of sputum ( P<0.05). The concentration methods by sedimentation, and centrifugation by the treatment of NaOCl, increased the sensitivity to 75% and 77.9%, respectively, and the specificity to 100% for both techniques. In conclusion, the use of NaOCl in the concentration of AFB in sputum is recommended for use in routine laboratory diagnosis of PTB in developing countries.

Sign in / Sign up

Export Citation Format

Share Document