Correlation between nosocomial pneumonia and ventilated patients in pediatric intensive care unit

Background NP (NP) especially YAP (ventilator-associated pneu-monia) is the most common infection in intensive care unit, whichcorrelates with the increasing of morbidity and mortality. Thereare some risk factors for development ofNP, the most importantone is duration of mechanical ventilator and reintubation.Objective To determine the correlation between NP and use ofmechanical ventilator in pediatric intensive care unit (PICU).Methods A matched case control study was conducted at Dr.Sardjito Hospital on all patients admitted to the PICU from2004 until 2006. Case group was defined as all patients who hadNP; age and sex matched control group included all patients notdiagnosed as NP. Statistical analysis was done by using chi-squareand t-tests as appropriate. Logistic regression analysis was doneto determine the role of risk factors.Results One-hundred and forty-one patients were included inthis study. The incidence of NP was 25. 7%. There was associa-tion between using mechanical ventilator (OR 1.08; 95%CI 1.07;8.20, P=0.036) and duration of using mechanical ventilator morethan four days (OR 1.75, 95%CI 1.87;18.02) with developmentof NP. There was a significant difference in event free survival ofNP between those using mechanical ventilator group and thosenot using mechanical ventilator group (P<O.OOl).Conclusion There is an association between the use of mechani-cal ventilator and duration of use of mechanical ventilator morethan four days with the development of NP

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Dialyzable Leukocyte Extract (Transferon™) Administration in Sepsis: Experience from a Single Referral Pediatric Intensive Care Unit

BioMed Research International ◽

10.1155/2019/8980506 ◽

2019 ◽

Vol 2019 ◽

pp. 1-10 ◽

Cited By ~ 4

Author(s):

Maria Isabel Castrejón Vázquez ◽

Aldo Arturo Reséndiz-Albor ◽

Mario A. Ynga-Durand ◽

Ivonne Maciel Arciniega Martínez ◽

Vanessa Ivonne Orellana-Villazon ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Laboratory Data ◽

Pediatric Intensive Care ◽

Control Group ◽

Immunomodulatory Agents ◽

Reactive Protein ◽

Significant Difference ◽

Pediatric Sepsis

Immunomodulatory agents have been proposed as therapeutic candidates to improve outcomes in sepsis. Transferon™, a dialyzable leukocyte extract (DLE), has been supported in Mexico as an immunomodulatory adjuvant in anti-infectious therapy. Here we present a retrospective study describing the experience of a referral pediatric intensive care unit (PICU) with Transferon™ in sepsis. We studied clinical and laboratory data from 123 patients with sepsis (15 in the DLE group and 108 in the control group) that were admitted to PICU during the period between January 2010 and December 2016. Transferon™ DLE use was associated with lower C reactive protein (CRP), increase in total lymphocyte counts (TLC), and decrease in total neutrophil count (TNC) 72 hours after Transferon™ DLE administration. The control group did not present any significant difference in CRP values and had lower TLC after 72 hours of admission. There was no difference in PICU length of stay between control and Transferon™ DLE group. Transferon™ DLE administration was associated with a higher survival rate at the end of PICU stay. This study shows a possible immunomodulatory effect of Transferon™ on pediatric sepsis patients.

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Predicting Candida Infection in Pediatric Intensive Care Unit using Candida Score in a Low-Resource Setting

Global Pediatric Health ◽

10.1177/2333794x21999152 ◽

2021 ◽

Vol 8 ◽

pp. 2333794X2199915

Author(s):

Dicky Ari Risandy ◽

Desy Rusmawatiningtyas ◽

Firdian Makrufardi ◽

Elisabeth Siti Herini ◽

Nurnaningsih

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Pediatric Intensive Care ◽

Candida Infection ◽

Control Group ◽

Case Group ◽

Resource Setting ◽

Low Resource Setting ◽

Candida Score

Candida infection was previously thought to be rare in intensive care. With the increased use of broad-spectrum antibiotics, the incidence of candida infection increased significantly. Case-control study was done in patients ≤18 years of age treated for 3 days or more in Pediatric Intensive Care Unit (PICU) Dr. Sardjito General Hospital, Yogyakarta from January 2014 to December 2016. Overall, 43 children were included in this study as a case group with positive candida culture and 43 children as a control group with no candida culture. Cut off point of candida score is ≥3 from our subjects. The area under curve (AUC) value for cut off ≥3 was moderate (0,72). Candida score ≥3 has an odd ratio (OR) 6.8 (95% CI 2.4-18.6) with P < .05. All of confounding factors in candida infection have no association with P > .05. Candida score can be used as predictor of candida infection in PICU.

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Evaluation of sound pressure levels in a pediatric intensive care unit

Open Science Journal ◽

10.23954/osj.v5i2.2415 ◽

2020 ◽

Vol 5 (2) ◽

Author(s):

Caroline De Araújo Mendes ◽

Carlos Roberto Lyra Da Silva ◽

Luciane Velasque De Souza ◽

Adriana Carla Bridi ◽

Joice Alves Cabral ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Sound Pressure ◽

Infusion Pump ◽

Pediatric Intensive Care ◽

Calibration Data ◽

Mechanical Ventilator ◽

Significant Difference ◽

Sound Pressure Levels

This study objectives were to measure the sound pressure levels found in the pediatric intensive care unit in a federal institution of Rio de Janeiro; to verify differences in noise levels during the morning and afternoon; to confront the sound pressure levels found against acceptable levels according to national and international noise organizations; to count the quantity of alarms triggered by each type of medical care equipment selected (multiparameter monitor, mechanical ventilator and infusion pump); to verify the relevance in the scientific world about pediatric intensive care unit noise through bibliometrics and to address the trinomial care technology - noise - implications on care. It’s an observational, exploratory, quantitative study, organized in three steps: Parameter collection and decibel meter calibration - data were based on the study by Salú, et al (2015) ; Data collection: 40 hours of discontinued observation (8am to 16pm) on different days for a period two months using two decibel meters; Data processing: An Excel spreadsheet was created for the database and data analysis was performed with the help of Microsoft Office Excel 2010 and Program R, organized into graphs and tables. 61% of the alarms corresponded to the mechanical ventilator; Bed E had the lowest standard deviation (SD = 2.945) and the highest median (69.5dBA). Even by removing the E bed from the analysis, there is a significant difference (p <0.001) between sound pressure levels. The median of the afternoon (28.2dBA); and morning (26.1dBA). Mechanical fan and monitor generated higher sounds; the pediatric intensive care unit has considerably exceeded that recommended by national and international noise organizations; afternoon generated higher sounds than morning. Keywords: Noise Meters; Noise; Intensive care; Pediatrics

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ROLE OF CONTINUOUS EEG MONITORING IN PEDIATRIC INTENSIVE CARE UNIT

Neuropediatrics ◽

10.1055/s-2006-945917 ◽

2006 ◽

Vol 37 (S 1) ◽

Author(s):

S Hosain ◽

G Solomon

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Pediatric Intensive Care ◽

Eeg Monitoring ◽

Continuous Eeg ◽

Continuous Eeg Monitoring

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Role of acute physiology and chronic health evaluation II scoring system in determining the severity and prognosis of critically ill patients in pediatric intensive care unit

Indian Journal of Critical Care Medicine ◽

10.4103/0972-5229.162463 ◽

2015 ◽

Vol 19 (8) ◽

pp. 462-465 ◽

Cited By ~ 1

Author(s):

N. P. Chhangani ◽

Minhas Amandeep ◽

Sandeep Choudhary ◽

Vidit Gupta ◽

Vishnu Goyal

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Critically Ill ◽

Pediatric Intensive Care Unit ◽

Critically Ill Patients ◽

Scoring System ◽

Pediatric Intensive Care ◽

Chronic Health Evaluation ◽

Health Evaluation

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The Role of Long-Term Electroencephalogram Monitoring in the Prognostic Evaluation of Children with Disturbance of Consciousness in Pediatric Intensive Care Unit

Tobacco Regulatory Science ◽

10.18001/trs.7.5.38 ◽

2021 ◽

Vol 7 (5) ◽

pp. 1214-1221

Author(s):

Xiaobo Wu ◽

Ruiqin Qiu ◽

Baoqi Li ◽

Heyuan Gao ◽

Ying Su

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Medical Records ◽

Compliance Rate ◽

Pediatric Intensive Care ◽

Prognostic Evaluation ◽

Disturbance Of Consciousness

This study aimed to investigate the role of long-term video electroencephalogram (VEEG) monitoring in the diagnosis and prognostic evaluation of children with disturbance of consciousness in pediatric intensive care unit (PICU). Materials and Methods : A retrospective analysis was performed on the medical records of 107 children with severe brain injury (SBI) who admitted to the PICU of The First Hospital of Qinhuangdao from January 2014 to December 2015. The medical records of 100 children with mild disturbance of consciousness were analyzed. All children underwent routine electroencephalogram (REEG) and VEEG detections. The diagnosis was completed by physicians according to the relevant operation instructions. The brain waveform of children was monitored. Result : The diagnostic results of REEG and VEEG were compared with clinical diagnostic results, and the relationship between the two detections and the prognosis of SBI children was analyzed. The sensitivity of VEEG in the diagnosis of SBI children was significantly higher than that of REEG (P<0.050). The specificity of VEEG in the diagnosis of SBI children was higher than that of REEG, with a statistical significance (P<0.050). The diagnostic compliance rate of VEEG in the diagnosis of SBI children was significantly higher than that of REEG (P<0.050). The sensitivity of VEEG in evaluating the prognosis of SBI children was significantly higher than that of REEG (P<0.050). The specificity of VEEG in evaluating the prognosis of SBI children was significantly higher than that of REEG. The coincidence rate of VEEG in evaluating the prognosis of SBI children was significantly higher than that of REEG (P<0.050). Conclusion: The results indicated that VEEG detection is effective in the diagnosis and prognostic evaluation of SBI children with disturbance of consciousness, which is worthy of promotion in clinical practice.

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