scholarly journals OBSERVATIONS ON BLOOD GROUP DISTRIBUTION IN PEPTIC ULCER PERFORATION AND GASTRIC PERFORATION

2016 ◽  
Vol 5 (96) ◽  
pp. 7060-7063
Author(s):  
Sureshkumar B ◽  
Rajavelu R ◽  
Udhayasankar V
1996 ◽  
Vol 49 (12) ◽  
pp. 1363-1371 ◽  
Author(s):  
Cecilie Svanes ◽  
Rolv T. Lie ◽  
Stein A. Lie ◽  
Gunnar Kvåle ◽  
Knut Svanes ◽  
...  

2021 ◽  
pp. 9-9
Author(s):  
Neelkamal Gupta ◽  
Mangtani Jitendra K ◽  
Khandelwal Dheeraj K

INTRODUCTION:Apeptic ulcer is a defect in the upper gastrointestinal mucosa that extends through the muscularis mucosa into deeper layers of the gut wall. Non-steroidal anti-inammatory drugs (NSAIDs) are the major risk factors for peptic ulcer disease.Long-term use of NSAIDs, however, can cause gastrointestinal (GI) ulcers and potentially life-threatening ulcer complications. MATERIALAND METHOD: The present study was conducted on 100 patients of peptic ulcer of either sex in Department of Surgery, Mahatma Gandhi Medical College & Hospital, Jaipur. History of any other co morbid illness and any drug being taken with its time duration were recorded in detail. RESULT AND DISCUSSION: From this study, it was observed that among the 69 patients of duodenal perforation, 73.91% were taking NSAID. Similarly among the 31 patients of gastric perforation 80.64% were taking NSAID. Overall total 76% patients were taking these drugs. CONCLUSION: It is concluded from this study that a strong statistical correlation was found between use of NSAIDs and peptic ulcer perforation.


1981 ◽  
Vol 17 (3) ◽  
pp. 448
Author(s):  
T H Kim ◽  
S W Kim ◽  
J S Lim ◽  
Y J Kim

2018 ◽  
Vol 35 (4) ◽  
pp. 282-288
Author(s):  
Ibtesam Khalid Salih ◽  
Ali Malik Sheya’a ◽  
Qays Ahmed Hassan ◽  
Ayad Khani Mykhan

Abstract The aim of this study was to evaluate the risk factors that influence the perforation, regardless of the presence of H. pylori infection, in a sample of Iraqi patients with peptic ulcers, admitted to Al-Kindy Teaching Hospital. A total of 90 patients who had perforated peptic ulcer participated in this study. The diagnosis was based on history, clinical examination, laboratory and radiological investigations and was confirmed intraoperatively. A number of probable risk factors for perforation were investigated. Eighty participants were males and 10 were females (male to female ratio 8:1). About 42.2% of patients were in their fifth decade of life. Forty-nine (54.4%) patients were asymptomatic before perforation occurred. Among the risk factors, smoking (66.7%), stress (60%) and blood group A (53.3%) play a significant risk for the occurrence of perforation. We concluded that smoking, stress, non-steroidal anti-inflammatory drugs, and to a lesser extent fasting and blood group A, play a major role as risk factors for the occurrence of peptic ulcer perforation. Other factors seem to play a minor role in this respect.


1998 ◽  
Vol 15 (3) ◽  
pp. 241-264 ◽  
Author(s):  
Cecilie Svanes ◽  
Robert B. Sothern ◽  
Halfdan Sørbye

2018 ◽  
Vol 27 (1) ◽  
pp. 4-9
Author(s):  
B Islam ◽  
A Sayed ◽  
I Ahmed ◽  
MA Hannan ◽  
MA Alam

Background: Peptic ulcer perforation is a common surgical problem in Bangladesh. For Muslims, the whole of the Ramadan is a time of strictly fasting during day time. Globally near one billion Muslims fast during this month. So it is an opportunity to evaluate the relationship between Ramadan fasting and peptic ulcer perforation. Present study was designed to evaluate the effect of fasting, socioeconomic condition, smoking and inadequate treatment of PUD on peptic ulcer perforation.TAJ 2014; 27(1): 4-9


2019 ◽  
Vol 2 (1) ◽  
pp. 4-10
Author(s):  
Sunit Agrawal ◽  
D Thakur ◽  
P Kafle ◽  
A Koirala ◽  
R K Sanjana ◽  
...  

Background: Helicobacter pylori is found in more than 90% cases of peptic ulcer. This study examines the possibility of association of Helicobacter pylori in perforated peptic ulcer disease and its relation to persisting ulcer as well as the influence of other risk factors; namely: smoking, alcohol, current non-steroidal anti inflammatory drugs (NSAIDs) and steroid use. Materials and Methods: In this prospective study, total of 50 cases of peptic ulcer perforation admitted in College of Medical Sciences and Teaching Hospital, Bharatpur, Nepal were selected on the basis of the non-probability (purposive) sampling method. All patients who presented with suspected peptic ulcer perforation were included in the study and the perforations were repaired by Modified Graham’s Patch and were given triple therapy postoperatively. The age, sex, incidence, mode of presentation, precipitating factors, association with the risk factors and postoperative complications were all evaluated and compared. Results: Of 50 patients studied, the age ranged from 17 to 75 years, mean age being 40.1 years with the peak incidence in the 3rd and 5th decades of life showing a male dominance (92%). H. pylori was seen in ulcer edge biopsy in 29 patients (58%). Most common clinical presentation was pain abdomen, the most common signs of perforation were tenderness, rebound tenderness and absent bowel sounds. The mean duration of stay in hospital in H. pylori positive patients was 12.07±8.15 days as compared with 11.1±5.12 days in H. pylori negative patients. The incidence of peptic ulcer perforation was higher in the patients consuming alcohol (64%) than smokers (48%), followed by NSAIDs user(22%). 20% of the patients with delayed presentation developed complications postoperatively. Perforated peptic ulcer was repaired by Modified Graham’s Patch Repair, followed by anti H. pylori therapy in all of them. Conclusion: Peptic ulcer perforation is quite common among the patients with peptic ulcer disease with history of chronic smoking, alcoholism and analgesic intake, more commonly in males. There is association of H. pylori in 58% of patients with peptic ulcer perforation.


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