scholarly journals COMPARATIVE STUDY OF LRINEC SCORE: PROCALCITONIN AND LRINEC SCORE: C-REACTIVE PROTEIN IN PREDICTING DURATION OF HOSPITAL STAY AND SEVERITY IN NECROTISING FASCIITIS

2016 ◽  
Vol 5 (51) ◽  
pp. 3248-3251
Author(s):  
Manoj Gowda Avalahalli ◽  
Pavan Kumar Muniraja ◽  
Mohammed Suhail Khalid ◽  
Kavitha Kaverappa ◽  
Lakshmi Devaraj ◽  
...  
2013 ◽  
Vol 94 (6) ◽  
pp. 826-831
Author(s):  
V A Gorbunov ◽  
R K Dzhordzhikiya ◽  
I I Vagizov ◽  
V A Abdulyanov ◽  
I V Abdulyanov ◽  
...  

Aim. To compare the effectiveness of poststernotomy mediastinitis treatment in 41 patients who underwent vacuum-assisted closure or closed irrigation treatment. Methods. A retrospective analysis of 41 cases of sternal wound infection identified in patients who underwent cardiac surgery between 2007 and 2012. 18 patients (the first group) were treated using closed irrigation, 23 patients (the second group) - using vacuum-assisted closure. We compared the time interval for wound healing and drainage, serum levels of C-reactive protein and blood leukocyte counts on admission and at different time points until discharge. Results. In patients who were treated using vacuum-assisted closure, wound debridement and healing were achieved at shorter terms, and lower rate of complications were observed. There were 8 (44.4%) relapses requiring repeated surgery and debridement in the first group compared to 3 (13%, p=0.01) in the second group. C-reactive protein level decreased more rapidly in patients who were treated using vacuum-assisted closure (p 0.02). The duration of hospital stay was 67±4.1 days in the first group compared to 29.6±8.4 days in the second group (p=0.019). Moreover, patients who were treated using vacuum-assisted closure did not experience any significant discomfort and stayed active. Histological examination of the soft tissues showed marked lymphoid and plasma-cell reaction and neoangiogenesis by the end of the second week of vacuum-assisted closure. Conclusion. The use of vacuum-assisted closure shortens the term of wound debridement, granulating tissue formation and the duration of hospital stay compared to closed irrigation treatment.


2021 ◽  
Vol 3 (1) ◽  
pp. 15-19
Author(s):  
Ahmet BEYAZ ◽  
Nurhan ATİLLA ◽  
Hüseyin ARPAĞ ◽  
Fulsen BOZKUŞ ◽  
Hasan KAHRAMAN ◽  
...  

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
Gabriele Corsi ◽  
Krashna Patel ◽  
Omar Abbassi ◽  
Zobia Gudkalli ◽  
David O’Hara ◽  
...  

Abstract Aim Oesophagectomy is associated with a significant number of potential complications affecting the lenght of the post-operative recovery. Serum C-reactive protein (CRP) is an acute phase protein which has been linked to early detection of post-operative complications, including but not limited to anastomotic leak. The aim of this retrospective study was to investigate the value of CRP elevation in the early post-operative days as a predictor of lenght of Hospital stay after minimally invasive oesophagectomy for cancer. Background and Methods The study group included 88 patients undergoing minimally invasive oesophagectomy for cancer from September 2017 to April 2019. CRP values on post-operative day 1,3,5 and 7 were retrieved and correlated to overall lenght of stay. Post-operative morbidity and mortality were also recorded. Results The approach was fully minimally invasive in 65 patients (74%) and hybrid in the remaining 23 (26%). The median length of stay was 11 days (IQR, 6-105 days) with overall mortality of 3.4% (n=3). Gastro-intestinal complications occurred in 15 patients (17%). The overall surgical or endoscopic re-intervention rate was 13.6% (n=12). The median CRP value was 54.8, 167, 143 and 134 mg/L, respectively on day 1,3,5 and 7. There was a positive correlation between CRP and length of stay on day 1, 3 and 7. A cut-off value of 167 mg/L on day 3 appeared to be a significant predictor of increased lenght of stay (12.8 vs 23.3 days, p=0.008). Conclusion CRP levels above 167mg/L on post-operative day 3 were associated with a prolonged lenght of hospital stay in our group of patients. Elevated CRP in the early post-operative period could represent a useful tool to predict lenght of stay after minimally invasive oesophagectomy.


1997 ◽  
Vol 205 (2) ◽  
pp. 151-156 ◽  
Author(s):  
J.L Ortega-Vinuesa ◽  
J.A Molina-Bolı́var ◽  
J.M Peula ◽  
R Hidalgo-Álvarez

2008 ◽  
Vol 74 (2) ◽  
pp. 160-167 ◽  
Author(s):  
Turkay Kirdak ◽  
Aysun Yilmazlar ◽  
Sinan Cavun ◽  
Ilker Ercan ◽  
Tuncay Yilmazlar

Preoperative single, high-dose methylprednisolone administration improves postoperative outcomes after colonic surgery. Several randomized studies, including major surgeries, assessed various high-dose steroid regimens; however, evidence about the effect of administration of lower doses on postoperative outcomes in colorectal surgery is not available. The aim of the present study is to determine whether the administration of a single, low dose of dexamethasone before surgery would confer an outcome advantage after colorectal surgery. Thirty patients undergoing colorectal surgery were included in this randomized, double-blind study. Patients received 8 mg dexamethasone or serum physiologic preoperatively. Levels of Interleukin-6 and C-reactive protein, pain scores, postoperative nausea and vomiting, mobilization, complications, hospital stay, and readmissions were compared. Age, sex, indications, and operations were similar in both groups ( P > 0.05). C-reactive protein and Interleukin-6 levels increased significantly postoperatively in each group ( P < 0.05), but there were no differences between groups when compared ( P > 0.05). There were also no significant differences between pain scores, bowel functions, mobilization, hospital stay, complication rates, and readmission rates between the two groups ( P > 0.05). Preoperative 8 mg dexamethasone administration has no significant effect on reducing postoperative inflammatory response and also does not improve outcomes of colorectal surgery.


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