Vitamin d supplementation explodes the triangle of danger \"iron deficiency anemia, inflammation and hypovitaminosis D in pediatric patients on hemodialysis

2016 ◽  
Vol 07 (02) ◽  
Author(s):  
Soha Abdelhady Ibrahim
Keyword(s):  
Vitamin D ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Pediatric Patients ◽  
Hypovitaminosis D ◽  
Vitamin D Supplementation ◽  
Deficiency Anemia

scholarly journals Reply: Intravenous Ferumoxytol in Pediatric Patients With Iron-Deficiency Anemia

2017 ◽  
Vol 51 (12) ◽  
pp. 1146-1146
Author(s):  
Nabil E. Hassan
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Pediatric Patients ◽  
Iron Absorption ◽  
Deficiency Anemia

Iron Deficiency in children is common problem. Its mechanism could be nutritional or due to lack of iron absorption. Several conditions are associated with IDA. Presence of inflammation further complicate attempts to make a definitive diagnoses or accurately quantify reponse to therapy.

Erythroferrone and iron status parameters levels in pediatric patients with iron deficiency anemia

2018 ◽  
Vol 100 (4) ◽  
pp. 356-360 ◽  
Author(s):  
Fady M. El Gendy ◽  
Mahmoud A. EL-Hawy ◽  
Amira M. F. Shehata ◽  
Hanaa E. Osheba
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Pediatric Patients ◽  
Iron Status ◽  
Deficiency Anemia

Effect of Vitamin D Replacement on Hemoglobin Concentration in Subjects with Concurrent Iron-Deficiency Anemia and Vitamin D Deficiency: A Randomized, Single-Blinded, Placebo-Controlled Trial

2014 ◽  
Vol 133 (1) ◽  
pp. 31-35 ◽  
Author(s):  
Basavraj Sooragonda ◽  
Sanjay Kumar Bhadada ◽  
Viral N. Shah ◽  
Pankaj Malhotra ◽  
Jasmina Ahluwalia ◽  
...  
Keyword(s):  
Vitamin D ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Controlled Trial ◽  
Hemoglobin Concentration ◽  
Deficiency Anemia ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Hb Concentration

Background: The effect of vitamin D replacement on hemoglobin (Hb) concentration in subjects with concurrent deficiencies of vitamin D and iron is not known. Methods: We report on an investigator-initiated, randomized, single-blinded, placebo-controlled, 12-week interventional trial. Thirty subjects with iron-deficiency anemia (serum ferritin <15 µg/l) were randomized to an intervention arm (cholecalciferol, i.e. vitamin D3, 0.6 million units i.m. once) or placebo. In all subjects, iron deficiency was corrected with parental iron. Other causes of anemia were excluded with appropriate investigation. The primary end point was a rise in Hb concentration. Results: Baseline parameters of age, BMI, hemogram values and levels of serum ferritin, 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH) were similar in the 2 arms. Twelve weeks after vitamin D replacement, there was a significant increase in 25 (OH)D levels (57.7 ± 20.5 vs. 14.1 ± 6.2 ng/ml, p < 0.0001) and a decrease in PTH levels (32.4 ± 16.4 vs. 52.9 ± 18.4 pg/ml, p = 0.003) in subjects in the intervention arm when compared to the placebo arm. However, the increments in serum ferritin and Hb concentration in the intervention and placebo arm did not differ. Conclusion: Vitamin D replacement in subjects with iron-deficiency anemia after iron correction does not improve Hb concentration further.

scholarly journals Evaluation of anemia frequency and etiologies in hospitalized patients in a tertiary pediatrics clinic

2021 ◽  
Vol 8 (12) ◽  
pp. 685-691
Author(s):  
İlhan Gürsoy ◽  
Emine Türkkan ◽  
Hüseyi̇n Dağ
Keyword(s):  
Chronic Disease ◽  
Iron Deficiency ◽  
General Population ◽  
Iron Deficiency Anemia ◽  
Pediatric Patients ◽  
Deficiency Anemia ◽  
Hospitalized Children ◽  
Anemia Of Chronic Disease ◽  
Number Of Patients ◽  
Hospitalization Period

Objective: Anemia, which is a public health problem on a global scale, continues to maintain its importance in pediatric patients. There are few studies on the prevalence of anemia in hospitalized children. This study was conducted to evaluate the prevalence and etiologies of anemia in hospitalized pediatric patients. Material and Method: This is a cross-sectional epidemiological study. The study group consists of 1000 patients between the ages of 6 months and 18 years who were hospitalized in the Department of Pediatrics of Prof. Dr. Cemil Tascioglu City Hospital. The data of the patients were reviewed retrospectively. The SPSS 22.0 program was used for statistical analyzes and calculations and p< 0.05 was accepted for significance. Results: Of the patients included in the study, 569 (56.9%) were male, and 431 (43.1%) were female. In the study, the number of patients with anemia was 276 (27.6%), and among those 151 (26.5%) were male and 125 (29.0%) were female. The highest rate of anemia in different age groups was in infancy, with 32.3%. The number of patients with iron deficiency anemia was 121 (43.8%), anemia of chronic disease was 42 (15.2%), anemia of acute inflammation was 41 (14.9%), and anemia due to B12 deficiency was 31 (11.2%). It was determined that patients with anemia had a longer hospital stay than those without anemia. Moreover, the hospitalization period of patients with anemia of chronic disease was longer than those with iron deficiency anemia. Conclusion: Anemia is an important problem in hospitalized children as well as in the general population. Iron deficiency is the most common etiology of anemia in hospitalized patients in the pediatric clinic similar to the general population. The hospitalization period was found to be significantly longer in anemic patients than in non-anemic patients. During hospitalization, children should be monitored for anemia and this duration of stay should be regarded as an opportunity to combat anemia or to provide necessary micronutrient or nutritional support to socioeconomically disadvantaged groups.

Intravenous Ferumoxytol in Pediatric Patients With Iron Deficiency Anemia

2017 ◽  
Vol 51 (7) ◽  
pp. 548-554 ◽  
Author(s):  
Nabil Hassan ◽  
Brian Boville ◽  
Diann Reischmann ◽  
Akunne Ndika ◽  
David Sterken ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Pediatric Patients ◽  
Deficiency Anemia

scholarly journals The association of vitamin D deficiency with iron deficiency anemia in Turkish children aged between 4 months to 5 years old

2021 ◽  
Author(s):  
Emine Çelik ◽  
Rukiye Saç ◽  
Nermin Dindar Badem ◽  
Yıldız Dallar Bilge ◽  
Bulent Alioglu
Keyword(s):  
Vitamin D ◽  
Iron Deficiency ◽  
Vitamin D Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Turkish Children ◽  
Group I ◽  
Vitamin D Levels ◽  
Group Ii ◽  
25 Oh Vitamin D

Objectives: Iron deficiency anemia (IDA) is most frequent in children under five years old. Many studies have shown a high prevalence of vitamin D deficiency (VDD) in similar age group. An association between IDA and VDD was reported. The objective of our study was to determine whether there is an association of VDD with IDA in Turkish children under 5 years old. Methods: Children, ages between four months-five years were included in a case–control study. Two groups were constituted: children with IDA (group I) and healthy control children without IDA (group II). Serum 25(OH) vitamin D levels lower than 20 ng/mL were considered as deficiency. Results: Mean age of group I (n=211, 24.8±17.5 months, 45% males) and group II (n=149, 26.4±17.7 months, 44% males) were comparable (p>0.05). Median vitamin D level in group I (22.5 ng/ml) was lower than group II (32.3 ng/mL) (p=0.001). The frequency of VDD was 38.5% in group I and 14.5% in group II (p<0.001). Sixteen children had subclinical rickets signs (All <36 months old); 14 of these were in group I (p=0.034). Conclusions: VDD is more frequent in small children with IDA than healthy controls. Most of the children presenting subclinical rickets signs had concurrent IDA. Physicians should note that VDD or even subclinical rickets may associate to IDA in children younger than 36 months old.

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